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Endocrine connections2014; 3(3); R81-R93; doi: 10.1530/EC-14-0038

Metabolic syndrome: is equine disease comparable to what we know in humans?

Abstract: This review summarizes similarities and differences between the metabolic syndromes in humans and equines, concerning the anatomy, symptoms, and pathophysiological mechanisms. In particular, it discusses the structure and distribution of adipose tissue and its specific metabolic pathways. Furthermore, this article provides insights and focuses on issues concerning laminitis in horses and cardiovascular diseases in humans, as well as their overlap.
© 2014 The authors.
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Publication Date: 2014-06-03 PubMed ID: 24894908PubMed Central: PMC4068110DOI: 10.1530/EC-14-0038Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article focuses on a comparative study between metabolic syndrome in humans and horses, exploring the similarities and differences in anatomy, symptoms, and related pathophysiological mechanisms.

Comparative study between humans and equines

  • This research article explores the metabolic syndrome in both humans and equines, providing an understanding of how the syndrome is similar or different between the two.
  • The comparison is drawn on various fronts including the structure and distribution of adipose tissue and metabolic pathways, which play a crucial role in metabolic syndrome.
  • The article examines the symptoms and physiological aspects of metabolic syndrome in both species, focusing on the way these symptoms appear, progress and can be managed.

Focus on specific symptoms

  • One of the major symptoms discussed in the research is laminitis, a disease that primarily affects horses. By studying this condition, the researchers are able to provide further insight into the metabolic mechanisms involved.
  • The article also touches on cardiovascular diseases in humans, which are closely associated with metabolic syndrome. Comparing these with laminitis in horses allows the researchers to explore potential overlaps and understand if treatments or preventative measures could also be shared.

Pathophysiological mechanisms

  • The article delves into the pathophysiological mechanisms involved in metabolic syndrome. These mechanisms are integral to understanding how the syndrome develops and progresses, allowing for targeted treatment.

Implications of the study

  • By drawing comparisons between metabolic syndrome in humans and horses, the study can potentially open avenues for shared treatment methods and measures to prevent the onset of the syndrome.
  • The study also contributes to a better understanding of metabolic syndrome in general, both in terms of its manifestation and treatment approaches.

Cite This Article

APA
Ertelt A, Barton AK, Schmitz RR, Gehlen H. (2014). Metabolic syndrome: is equine disease comparable to what we know in humans? Endocr Connect, 3(3), R81-R93. https://doi.org/10.1530/EC-14-0038

Publication

Endocrine connections
ISSN: 2049-3614
NlmUniqueID: 101598413
Country: England
Language: English
Volume: 3
Issue: 3
Pages: R81-R93

Researcher Affiliations

Ertelt, Antonia
  • Equine ClinicFree University of Berlin, Berlin, Germany antonia.ertelt@fu-berlin.de.
Barton, Ann-Kristin
  • Equine ClinicFree University of Berlin, Berlin, Germany.
Schmitz, Robert R
  • Equine ClinicFree University of Berlin, Berlin, Germany.
Gehlen, Heidrun
  • Equine ClinicFree University of Berlin, Berlin, Germany.

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