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Emerging infectious diseases2006; 11(12); 1942-1944; doi: 10.3201/eid1112.050241

Methicillin-resistant staphylococci in companion animals.

Abstract: We determined the molecular characteristics of methicillin-resistant staphylococci from animals and staff at a small animal and equine hospital. Methicillin-resistant Staphylococcus aureus (MRSA) identical to human EMRSA-15 was found in dogs and hospital staff. In contrast, 5 distinct MRSA strains were isolated from horses but not from hospital staff.
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Publication Date: 2006-02-21 PubMed ID: 16485485PubMed Central: PMC3367626DOI: 10.3201/eid1112.050241Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study investigates the types of Methicillin-resistant staphylococcus bacteria found in pets and the staff of a veterinary hospital. The same type of bacteria that is found in humans was found in dogs and hospital staff, while horses had five distinct types, none of which were found in the hospital staff.

Objectives of the study

  • The purpose of this research was to classify the various strains of Methicillin-resistant staphylococci in animals and the staff of a small animal and equine hospital.

Methods

  • This study was conducted in a hospital environment treating small animals and horses.
  • Presumably, the bacteria were collected and cultured from a variety of samples across the animal and human subjects.
  • Given the nature of the study, molecular biology techniques were supposed to be utilised to investigate the genetic properties of the collected bacteria.

Findings

  • The research article reports that an identical strain of methicillin-resistant Staphylococcus aureus (MRSA), known as human EMRSA-15, was identified in both dogs and hospital staff.
  • This conclusion suggests a possible transmission of the MRSA bacteria back and forth between dogs and humans, possible due to the close quarters and frequent interactions in a hospital environment.
  • Contrarily, five distinct strains of MRSA were identified in horses.
  • These equine strains of MRSA were not found in the hospital staff, suggesting these strains may be specific to horses or uncommonly transmitted to humans.

Conclusions and implications

  • This study shows that different strains of Methicillin-resistant staphylococci bacteria can be found in different species and, possibly, transmitted across species as well.
  • The findings in this study point to the necessity of infection control measures in veterinary practices to prevent the transmission of MRSA and other bacteria among animals and humans.
  • A better understanding of the types of bacteria present in different species can offer help in improving treatment outcomes and antibiotic use within veterinary medicine.

Cite This Article

APA
Baptiste KE, Williams K, Willams NJ, Wattret A, Clegg PD, Dawson S, Corkill JE, O'Neill T, Hart CA. (2006). Methicillin-resistant staphylococci in companion animals. Emerg Infect Dis, 11(12), 1942-1944. https://doi.org/10.3201/eid1112.050241

Publication

Emerging infectious diseases
ISSN: 1080-6040
NlmUniqueID: 9508155
Country: United States
Language: English
Volume: 11
Issue: 12
Pages: 1942-1944

Researcher Affiliations

Baptiste, Keith E
  • University of Liverpool, Leahurst, United Kingdom.
Williams, Kerry
    Willams, Nicola J
      Wattret, Andrew
        Clegg, Peter D
          Dawson, Susan
            Corkill, John E
              O'Neill, Turlough
                Hart, C Anthony

                  MeSH Terms

                  • Animals
                  • Carrier State / microbiology
                  • Cats / microbiology
                  • Dogs / microbiology
                  • Horses / microbiology
                  • Hospitals, Animal
                  • Humans
                  • Methicillin Resistance
                  • Nose / microbiology
                  • Perineum / microbiology
                  • Skin / microbiology
                  • Staphylococcal Infections / epidemiology
                  • Staphylococcal Infections / microbiology
                  • Staphylococcal Infections / veterinary
                  • Staphylococcus aureus / drug effects
                  • Staphylococcus aureus / isolation & purification

                  References

                  This article includes 15 references
                  1. Tomlin J, Pead MJ, Lloyd DH, Howell S, Hartmann R, Jackson HA. Methicillin-resistant Staphylococcus aureus infections in 11 dogs. Vet Rec 1999;144:60–4.
                    doi: 10.1136/vr.144.3.60pubmed: 10070689google scholar: lookup
                  2. Boag A, Loeffler A, Lloyd DH. Methicillin-resistant Staphylococcus aureus isolates from companion animals. Vet Rec 2004;154:11.
                    pubmed: 15083981
                  3. Manian FA. Asymptomatic nasal carriage of mupirocin, methicillin-resistant Staphylococcus aureus (MRSA) in a pet dog associated with MRSA infection in household contacts. Clin Infect Dis 2003;36:e26–8. Epub 2003 Jan 6.
                    doi: 10.1086/344772pubmed: 12522764google scholar: lookup
                  4. van Duijkeren E, Wolfhagen MJHM, Box ATA, Heck MEOC, Wannet WJB, Fluit AC. Human-to-dog transmission of methicillin-resistant Staphylococcus aureus. Emerg Infect Dis 2004;10:2235–7.
                    pmc: PMC3323405pubmed: 15663871
                  5. Hartmann FA, Trostle SS, Klohnen AA. Isolation of methicillin-resistant Staphylococcus aureus from a postoperative wound infection in a horse. J Am Vet Med Assoc 1997;211:1558–61.
                    pubmed: 9290826
                  6. Seguin JC, Walker RD, Caron JP, Kloos WE, George CG, Hollis RJ. Methicillin-resistant Staphylococcus aureus outbreak in a veterinary teaching hospital: potential human-to-animal-transmission. J Clin Microbiol 1999;37:1459–63.
                    pmc: PMC84801pubmed: 10203505
                  7. Shimizu A, Kawano J, Yamamoto C, Kakutani O, Anzai T, Kamada M. Genetic analysis of equine methicillin-resistant Staphylococcus aureus by pulsed-field gel electrophoresis. J Vet Med Sci 1997;59:935–7.
                    doi: 10.1292/jvms.59.935pubmed: 9362045google scholar: lookup
                  8. Weese JS, Archambault M, Willey BM, Dick H, Hearn P, Kreiswirth BN. Methicillin-resistant Staphylococcus aureus in horses and horse personnel, 2000–2002. Emerg Infect Dis 2005;11:430–5.
                    pmc: PMC3298236pubmed: 15757559
                  9. Andrews JM; BSAC Working Party on Susceptibility Testing. BSAC standardized disc susceptibility testing method. J Antimicrob Chemother 2001;48(Suppl 1):43–57.
                    doi: 10.1093/jac/48.suppl_1.43pubmed: 11420336google scholar: lookup
                  10. Senna JPM, Pinto CA, Carvalho LPS, Santos DS. Comparison of pulsed-field gel electrophoresis and PCR analysis of polymorphisms on the mec hypervariable region for typing methicillin-resistant Staphylococcus aureus. J Clin Microbiol 2002;40:2254–6.
                    doi: 10.1128/JCM.40.6.2254-2256.2002pmc: PMC130718pubmed: 12037102google scholar: lookup
                  11. Vannuffel P, Gigi J, Ezzedine H, Vandercam B, Delmee M, Wauters G. Specific detection of methicillin-resistant Staphylococcus species by multiplex PCR. J Clin Microbiol 1995;33:2864–7.
                    pmc: PMC228596pubmed: 8576335
                  12. Francois P, Pittet D, Bento M, Pepey B, Vaudaux P, Lew D. Rapid detection of methicillin-resistant Staphylococcus aureus directly from sterile or non-sterile clinical samples by a new molecular assay. J Clin Microbiol 2003;41:254–60.
                    doi: 10.1128/JCM.41.1.254-260.2003pmc: PMC149566pubmed: 12517857google scholar: lookup
                  13. Corkill JE, Anson JJ, Griffiths P, Hart CA. Detection of elements of the staphylococcal cassette chromosome (SCC) in a methicillin-susceptible (mecA gene negative) homologue of a fucidin-resistant MRSA. J Antimicrob Chemother 2004;54:229–31.
                    doi: 10.1093/jac/dkh284pubmed: 15150163google scholar: lookup
                  14. Lina G, Piemont Y, Godail-Gamot F, Bes M, Peter MO, Gauduchon V. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 1999;29:1128–32.
                    doi: 10.1086/313461pubmed: 10524952google scholar: lookup
                  15. Murchan S, Kaufmann ME, Deplano A, Ryck R, Struelens M, Zinn CE. Harmonisation of pulsed field gel electrophoresis protocols for epidemiological typing of strains of methicillin-resistant Staphylococcus aureus: a single approach developed by consensus in 10 European laboratories and its application for tracing the spread of related strains. J Clin Microbiol 2003;41:1574–85.
                    doi: 10.1128/JCM.41.4.1574-1585.2003pmc: PMC153895pubmed: 12682148google scholar: lookup

                  Citations

                  This article has been cited 67 times.
                  1. Popa I, Iancu I, Iorgoni V, Degi J, Gligor A, Imre K, Tîrziu E, Bochiș T, Pop C, Plotuna AM, Nistor P, Pentea M, Herman V, Nichita I. Prevalence and Antimicrobial Resistance of Staphylococcus aureus and Staphylococcus schleiferi Isolated from Dogs with Otitis Externa and Healthy Dogs. Antibiotics (Basel) 2025 Nov 24;14(12).
                    doi: 10.3390/antibiotics14121194pubmed: 41463697google scholar: lookup
                  2. Dewulf S, Boyen F, Paepe D, Clercx C, Tilman N, Dewulf J, Boland C. Antimicrobial Resistance Characterization of Methicillin-Resistant Staphylococcus aureus and Staphylococcus pseudintermedius Isolates from Clinical Cases in Dogs and Cats in Belgium. Antibiotics (Basel) 2025 Jun 20;14(7).
                    doi: 10.3390/antibiotics14070631pubmed: 40723934google scholar: lookup
                  3. Kabir A, Lamichhane B, Habib T, Adams A, El-Sheikh Ali H, Slovis NM, Troedsson MHT, Helmy YA. Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond-A Comprehensive Review. Antibiotics (Basel) 2024 Jul 29;13(8).
                    doi: 10.3390/antibiotics13080713pubmed: 39200013google scholar: lookup
                  4. Gustafsson L, Wikström C, Mueller RS, Bergvall K. Microbes on Clipper Blades after Use and Disinfection in Small Animal- and Equine Practice. Vet Sci 2024 Jan 17;11(1).
                    doi: 10.3390/vetsci11010038pubmed: 38250944google scholar: lookup
                  5. Akarsu H, Liljander AM, Lacasta A, Ssajjakambwe P, Brodard I, Cherbuin JDR, Torres-Puig S, Perreten V, Kuhnert P, Labroussaa F, Jores J. Canine Staphylococcaceae circulating in a Kenyan animal shelter. Microbiol Spectr 2024 Feb 6;12(2):e0292423.
                    doi: 10.1128/spectrum.02924-23pubmed: 38206027google scholar: lookup
                  6. Immergluck LC, Lin X, Geng R, Edelson M, Ali F, Li C, Lin TJ, Khalida C, Piper-Jenks N, Pardos de la Gandara M, de Lencastre H, Tomasz A, Evering TH, Kost RG, Vaughan R, Tobin JN. Molecular Epidemiologic and Geo-Spatial Characterization of Staphylococcus aureus Cultured from Skin and Soft Tissue Infections from United States-Born and Immigrant Patients Living in New York City. Antibiotics (Basel) 2023 Oct 14;12(10).
                    doi: 10.3390/antibiotics12101541pubmed: 37887242google scholar: lookup
                  7. Khairullah AR, Sudjarwo SA, Effendi MH, Ramandinianto SC, Gelolodo MA, Widodo A, Riwu KHP, Kurniawati DA. Pet animals as reservoirs for spreading methicillin-resistant Staphylococcus aureus to human health. J Adv Vet Anim Res 2023 Mar;10(1):1-13.
                    doi: 10.5455/javar.2023.j641pubmed: 37155545google scholar: lookup
                  8. Nwobi OC, Anyanwu MU, Jaja IF, Nwankwo IO, Okolo CC, Nwobi CA, Ezenduka EV, Oguttu JW. Staphylococcus aureus in Horses in Nigeria: Occurrence, Antimicrobial, Methicillin and Heavy Metal Resistance and Virulence Potentials. Antibiotics (Basel) 2023 Jan 24;12(2).
                    doi: 10.3390/antibiotics12020242pubmed: 36830153google scholar: lookup
                  9. Shoaib M, Aqib AI, Muzammil I, Majeed N, Bhutta ZA, Kulyar MF, Fatima M, Zaheer CF, Muneer A, Murtaza M, Kashif M, Shafqat F, Pu W. MRSA compendium of epidemiology, transmission, pathophysiology, treatment, and prevention within one health framework. Front Microbiol 2022;13:1067284.
                    doi: 10.3389/fmicb.2022.1067284pubmed: 36704547google scholar: lookup
                  10. Gehlen H, Klein KS, Merle R, Lübke-Becker A, Stoeckle SD. Does colonization with MRSA, ESBL - producing Enterobacteriaceae, and/or Acinetobacter baumannii - increase the risk for postoperative surgical site infection?. Vet Med Sci 2023 Mar;9(2):729-737.
                    doi: 10.1002/vms3.1073pubmed: 36646070google scholar: lookup
                  11. Belhout C, Elgroud R, Butaye P. Methicillin-Resistant Staphylococcus aureus (MRSA) and Other Methicillin-Resistant Staphylococci and Mammaliicoccus (MRNaS) Associated with Animals and Food Products in Arab Countries: A Review. Vet Sci 2022 Jun 24;9(7).
                    doi: 10.3390/vetsci9070317pubmed: 35878334google scholar: lookup
                  12. Soza-Ossandón P, Rivera D, Allel K, González-Rocha G, Quezada-Aguiluz M, San Martin I, García P, Moreno-Switt AI. Mec-Positive Staphylococcus Healthcare-Associated Infections Presenting High Transmission Risks for Antimicrobial-Resistant Strains in an Equine Hospital. Antibiotics (Basel) 2022 May 4;11(5).
                    doi: 10.3390/antibiotics11050621pubmed: 35625265google scholar: lookup
                  13. Nielsen SS, Bicout DJ, Calistri P, Canali E, Drewe JA, Garin-Bastuji B, Gonzales Rojas JL, Gortázar C, Herskin M, Michel V, Miranda Chueca MÁ, Padalino B, Pasquali P, Roberts HC, Spoolder H, Ståhl K, Velarde A, Viltrop A, Winckler C, Baldinelli F, Broglia A, Kohnle L, Alvarez J. Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): antimicrobial-resistant Staphylococcus aureus in cattle and horses. EFSA J 2022 May;20(5):e07312.
                    doi: 10.2903/j.efsa.2022.7312pubmed: 35582361google scholar: lookup
                  14. Yang D, Heederik DJJ, Scherpenisse P, Van Gompel L, Luiken REC, Wadepohl K, Skarżyńska M, Van Heijnsbergen E, Wouters IM, Greve GD, Jongerius-Gortemaker BGM, Tersteeg-Zijderveld M, Portengen L, Juraschek K, Fischer J, Zając M, Wasyl D, Wagenaar JA, Mevius DJ, Smit LAM, Schmitt H. Antimicrobial resistance genes aph(3')-III, erm(B), sul2 and tet(W) abundance in animal faeces, meat, production environments and human faeces in Europe. J Antimicrob Chemother 2022 Jun 29;77(7):1883-1893.
                    doi: 10.1093/jac/dkac133pubmed: 35466367google scholar: lookup
                  15. Tahoun A, Elnafarawy HK, El-Sharkawy H, Rizk AM, Alorabi M, El-Shehawi AM, Youssef MA, Ibrahim HMM, El-Khodery S. The Prevalence and Molecular Biology of Staphylococcus aureus Isolated from Healthy and Diseased Equine Eyes in Egypt. Antibiotics (Basel) 2022 Feb 10;11(2).
                    doi: 10.3390/antibiotics11020221pubmed: 35203823google scholar: lookup
                  16. Cocca G, Piva S, Magno SD, Scarpellini R, Giacometti F, Serraino A, Giunti M. Prevalence and Patterns of Antimicrobial Resistance among Escherichia coli and Staphylococcus spp. in a Veterinary University Hospital. Vet Sci 2021 Dec 6;8(12).
                    doi: 10.3390/vetsci8120308pubmed: 34941835google scholar: lookup
                  17. Neut C. Carriage of Multidrug-Resistant Bacteria in Healthy People: Recognition of Several Risk Groups. Antibiotics (Basel) 2021 Sep 25;10(10).
                    doi: 10.3390/antibiotics10101163pubmed: 34680744google scholar: lookup
                  18. Crespo-Piazuelo D, Lawlor PG. Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) prevalence in humans in close contact with animals and measures to reduce on-farm colonisation. Ir Vet J 2021 Aug 6;74(1):21.
                    doi: 10.1186/s13620-021-00200-7pubmed: 34362463google scholar: lookup
                  19. Othman AA, Hiblu MA, Abbassi MS, Abouzeed YM, Ahmed MO. Nasal colonization and antibiotic resistance patterns of Staphylococcus species isolated from healthy horses in Tripoli, Libya. J Equine Sci 2021 Jun;32(2):61-65.
                    doi: 10.1294/jes.32.61pubmed: 34220273google scholar: lookup
                  20. Hemeg HA. Determination of phylogenetic relationships among methicillin-resistant Staphylococcus aureus recovered from infected humans and Companion Animals. Saudi J Biol Sci 2021 Apr;28(4):2098-2101.
                    doi: 10.1016/j.sjbs.2021.01.017pubmed: 33911925google scholar: lookup
                  21. Roudaud M, Allano M, Fairbrother JH, Sauvé F. A retrospective study on methicillin-resistant Staphylococcus spp. isolated from horses admitted to a Canadian veterinary teaching hospital between 2008 and 2018. Can Vet J 2020 Nov;61(11):1197-1202.
                    pubmed: 33149358
                  22. Jaradat ZW, Ababneh QO, Sha'aban ST, Alkofahi AA, Assaleh D, Al Shara A. Methicillin Resistant Staphylococcus aureus and public fomites: a review. Pathog Glob Health 2020 Dec;114(8):426-450.
                    doi: 10.1080/20477724.2020.1824112pubmed: 33115375google scholar: lookup
                  23. Dalton KR, Rock C, Carroll KC, Davis MF. One Health in hospitals: how understanding the dynamics of people, animals, and the hospital built-environment can be used to better inform interventions for antimicrobial-resistant gram-positive infections. Antimicrob Resist Infect Control 2020 Jun 1;9(1):78.
                    doi: 10.1186/s13756-020-00737-2pubmed: 32487220google scholar: lookup
                  24. Gutierrez L, Tapia G, Ocampo L, Monroy-Barreto M, Sumano H. Oral Plus Topical Administration of Enrofloxacin-Hydrochloride-Dihydrate for the Treatment of Unresponsive Canine Pyoderma. A Clinical Trial. Animals (Basel) 2020 May 29;10(6).
                    doi: 10.3390/ani10060943pubmed: 32485942google scholar: lookup
                  25. Ma GC, Worthing KA, Ward MP, Norris JM. Commensal Staphylococci Including Methicillin-Resistant Staphylococcus aureus from Dogs and Cats in Remote New South Wales, Australia. Microb Ecol 2020 Jan;79(1):164-174.
                    doi: 10.1007/s00248-019-01382-ypubmed: 31049616google scholar: lookup
                  26. Rusdi B, Laird T, Abraham R, Ash A, Robertson ID, Mukerji S, Coombs GW, Abraham S, O'Dea MA. Carriage of critically important antimicrobial resistant bacteria and zoonotic parasites amongst camp dogs in remote Western Australian indigenous communities. Sci Rep 2018 Jun 7;8(1):8725.
                    doi: 10.1038/s41598-018-26920-5pubmed: 29880792google scholar: lookup
                  27. Allcock S, Young EH, Holmes M, Gurdasani D, Dougan G, Sandhu MS, Solomon L, Török ME. Antimicrobial resistance in human populations: challenges and opportunities. Glob Health Epidemiol Genom 2017;2:e4.
                    doi: 10.1017/gheg.2017.4pubmed: 29276617google scholar: lookup
                  28. Ahangari Z, Ghorbanpoor M, Shapouri MRS, Gharibi D, Ghazvini K. Methicillin resistance and selective genetic determinants of Staphylococcus aureus isolates with bovine mastitis milk origin. Iran J Microbiol 2017 Jun;9(3):152-159.
                    pubmed: 29225754
                  29. Bortolami A, Williams NJ, McGowan CM, Kelly PG, Archer DC, Corrò M, Pinchbeck G, Saunders CJ, Timofte D. Environmental surveillance identifies multiple introductions of MRSA CC398 in an Equine Veterinary Hospital in the UK, 2011-2016. Sci Rep 2017 Jul 14;7(1):5499.
                    doi: 10.1038/s41598-017-05559-8pubmed: 28710350google scholar: lookup
                  30. Boyle AG, Rankin SC, Duffee LA, Morris D. Prevalence of Methicillin-Resistant Staphylococcus aureus from Equine Nasopharyngeal and Guttural Pouch Wash Samples. J Vet Intern Med 2017 Sep;31(5):1551-1555.
                    doi: 10.1111/jvim.14783pubmed: 28661019google scholar: lookup
                  31. Bierowiec K, Płoneczka-Janeczko K, Rypuła K. Prevalence and Risk Factors of Colonization with Staphylococcus aureus in Healthy Pet Cats Kept in the City Households. Biomed Res Int 2016;2016:3070524.
                    doi: 10.1155/2016/3070524pubmed: 27766257google scholar: lookup
                  32. Lozano C, Gharsa H, Ben Slama K, Zarazaga M, Torres C. Staphylococcus aureus in Animals and Food: Methicillin Resistance, Prevalence and Population Structure. A Review in the African Continent. Microorganisms 2016 Feb 4;4(1).
                    doi: 10.3390/microorganisms4010012pubmed: 27681906google scholar: lookup
                  33. Wang L, Xue H, Li L, Zhao X. Characterization of Insertion Sequence ISSau2 in the Human and Livestock-Associated Staphylococcus aureus. PLoS One 2015;10(5):e0127183.
                    doi: 10.1371/journal.pone.0127183pubmed: 25978410google scholar: lookup
                  34. van de Sande-Bruinsma N, Leverstein van Hall MA, Janssen M, Nagtzaam N, Leenders S, de Greeff SC, Schneeberger PM. Impact of livestock-associated MRSA in a hospital setting. Antimicrob Resist Infect Control 2015;4:11.
                    doi: 10.1186/s13756-015-0053-8pubmed: 25908965google scholar: lookup
                  35. Mehndiratta PL, Bhalla P. Use of antibiotics in animal agriculture & emergence of methicillin-resistant Staphylococcus aureus (MRSA) clones: need to assess the impact on public health. Indian J Med Res 2014 Sep;140(3):339-44.
                    pubmed: 25366200
                  36. Chah KF, Gómez-Sanz E, Nwanta JA, Asadu B, Agbo IC, Lozano C, Zarazaga M, Torres C. Methicillin-resistant coagulase-negative staphylococci from healthy dogs in Nsukka, Nigeria. Braz J Microbiol 2014;45(1):215-20.
                    doi: 10.1590/S1517-83822014005000034pubmed: 24948934google scholar: lookup
                  37. van Balen J, Mowery J, Piraino-Sandoval M, Nava-Hoet RC, Kohn C, Hoet AE. Molecular epidemiology of environmental MRSA at an equine teaching hospital: introduction, circulation and maintenance. Vet Res 2014 Mar 19;45(1):31.
                    doi: 10.1186/1297-9716-45-31pubmed: 24641543google scholar: lookup
                  38. Ciftci A, Findik A, Onuk EE, Savasan S. Detection of methicillin resistance and slime factor production of Staphylococcus aureus in bovine mastitis. Braz J Microbiol 2009 Apr;40(2):254-61.
                    doi: 10.1590/S1517-83822009000200009pubmed: 24031354google scholar: lookup
                  39. Rinsky JL, Nadimpalli M, Wing S, Hall D, Baron D, Price LB, Larsen J, Stegger M, Stewart J, Heaney CD. Livestock-associated methicillin and multidrug resistant Staphylococcus aureus is present among industrial, not antibiotic-free livestock operation workers in North Carolina. PLoS One 2013;8(7):e67641.
                    doi: 10.1371/journal.pone.0067641pubmed: 23844044google scholar: lookup
                  40. Mallardo K, Nizza S, Fiorito F, Pagnini U, De Martino L. A comparative evaluation of methicillin-resistant staphylococci isolated from harness racing-horses, breeding mares and riding-horses in Italy. Asian Pac J Trop Biomed 2013 Mar;3(3):169-73.
                    doi: 10.1016/S2221-1691(13)60044-1pubmed: 23620832google scholar: lookup
                  41. Barton M, Hawkes M, Moore D, Conly J, Nicolle L, Allen U, Boyd N, Embree J, Van Horne L, Le Saux N, Richardson S, Moore A, Tran D, Waters V, Vearncombe M, Katz K, Weese JS, Embil J, Ofner-Agostini M, Ford-Jones EL. Guidelines for the prevention and management of community-associated methicillin-resistant Staphylococcus aureus: A perspective for Canadian health care practitioners. Can J Infect Dis Med Microbiol 2006 Sep;17 Suppl C(Suppl C):4C-24C.
                    pubmed: 23365589
                  42. Davis MF, Peterson AE, Julian KG, Greene WH, Price LB, Nelson K, Whitener CJ, Silbergeld EK. Household risk factors for colonization with multidrug-resistant Staphylococcus aureus isolates. PLoS One 2013;8(1):e54733.
                    doi: 10.1371/journal.pone.0054733pubmed: 23359808google scholar: lookup
                  43. Vincze S, Stamm I, Monecke S, Kopp PA, Semmler T, Wieler LH, Lübke-Becker A, Walther B. Molecular analysis of human and canine Staphylococcus aureus strains reveals distinct extended-host-spectrum genotypes independent of their methicillin resistance. Appl Environ Microbiol 2013 Jan;79(2):655-62.
                    doi: 10.1128/AEM.02704-12pubmed: 23160118google scholar: lookup
                  44. Aklilu E, Zakaria Z, Hassan L, Hui Cheng C. Molecular relatedness of methicillin-resistant S. aureus isolates from staff, environment and pets at University Veterinary Hospital in Malaysia. PLoS One 2012;7(8):e43329.
                    doi: 10.1371/journal.pone.0043329pubmed: 22937034google scholar: lookup
                  45. Karakulska J, Fijałkowski K, Nawrotek P, Pobucewicz A, Poszumski F, Czernomysy-Furowicz D. Identification and methicillin resistance of coagulase-negative staphylococci isolated from nasal cavity of healthy horses. J Microbiol 2012 Jun;50(3):444-51.
                    doi: 10.1007/s12275-012-1550-6pubmed: 22752908google scholar: lookup
                  46. Pantosti A. Methicillin-Resistant Staphylococcus aureus Associated with Animals and Its Relevance to Human Health. Front Microbiol 2012;3:127.
                    doi: 10.3389/fmicb.2012.00127pubmed: 22509176google scholar: lookup
                  47. Marano N, Arguin P, Pappaioanou M, King L. Role of multisector partnerships in controlling emerging zoonotic diseases. Emerg Infect Dis 2005 Dec;11(12):1813-4.
                    doi: 10.3201/eid1112.051322pubmed: 22289146google scholar: lookup
                  48. Ferreira JP, Anderson KL, Correa MT, Lyman R, Ruffin F, Reller LB, Fowler VG Jr. Transmission of MRSA between companion animals and infected human patients presenting to outpatient medical care facilities. PLoS One 2011;6(11):e26978.
                    doi: 10.1371/journal.pone.0026978pubmed: 22102871google scholar: lookup
                  49. Xue H, Lu H, Zhao X. Sequence diversities of serine-aspartate repeat genes among Staphylococcus aureus isolates from different hosts presumably by horizontal gene transfer. PLoS One 2011;6(5):e20332.
                    doi: 10.1371/journal.pone.0020332pubmed: 21625460google scholar: lookup
                  50. Abrahamian FM, Goldstein EJ. Microbiology of animal bite wound infections. Clin Microbiol Rev 2011 Apr;24(2):231-46.
                    doi: 10.1128/CMR.00041-10pubmed: 21482724google scholar: lookup
                  51. Hoet AE, Johnson A, Nava-Hoet RC, Bateman S, Hillier A, Dyce J, Gebreyes WA, Wittum TE. Environmental methicillin-resistant Staphylococcus aureus in a veterinary teaching hospital during a nonoutbreak period. Vector Borne Zoonotic Dis 2011 Jun;11(6):609-15.
                    doi: 10.1089/vbz.2010.0181pubmed: 21417926google scholar: lookup
                  52. David MZ, Daum RS. Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic. Clin Microbiol Rev 2010 Jul;23(3):616-87.
                    doi: 10.1128/CMR.00081-09pubmed: 20610826google scholar: lookup
                  53. McCarthy AJ, Lindsay JA. Genetic variation in Staphylococcus aureus surface and immune evasion genes is lineage associated: implications for vaccine design and host-pathogen interactions. BMC Microbiol 2010 Jun 15;10:173.
                    doi: 10.1186/1471-2180-10-173pubmed: 20550675google scholar: lookup
                  54. Soares Magalhães RJ, Loeffler A, Lindsay J, Rich M, Roberts L, Smith H, Lloyd DH, Pfeiffer DU. Risk factors for methicillin-resistant Staphylococcus aureus (MRSA) infection in dogs and cats: a case-control study. Vet Res 2010 Sep-Oct;41(5):55.
                    doi: 10.1051/vetres/2010028pubmed: 20423695google scholar: lookup
                  55. Yamamoto T, Nishiyama A, Takano T, Yabe S, Higuchi W, Razvina O, Shi D. Community-acquired methicillin-resistant Staphylococcus aureus: community transmission, pathogenesis, and drug resistance. J Infect Chemother 2010 Aug;16(4):225-54.
                    doi: 10.1007/s10156-010-0045-9pubmed: 20336341google scholar: lookup
                  56. Shore AC, Rossney AS, Kinnevey PM, Brennan OM, Creamer E, Sherlock O, Dolan A, Cunney R, Sullivan DJ, Goering RV, Humphreys H, Coleman DC. Enhanced discrimination of highly clonal ST22-methicillin-resistant Staphylococcus aureus IV isolates achieved by combining spa, dru, and pulsed-field gel electrophoresis typing data. J Clin Microbiol 2010 May;48(5):1839-52.
                    doi: 10.1128/JCM.02155-09pubmed: 20335411google scholar: lookup
                  57. Hanselman BA, Kruth SA, Rousseau J, Weese JS. Coagulase positive staphylococcal colonization of humans and their household pets. Can Vet J 2009 Sep;50(9):954-8.
                    pubmed: 19949556
                  58. Loh JV, Percival SL, Woods EJ, Williams NJ, Cochrane CA. Silver resistance in MRSA isolated from wound and nasal sources in humans and animals. Int Wound J 2009 Feb;6(1):32-8.
                    doi: 10.1111/j.1742-481X.2008.00563.xpubmed: 19291113google scholar: lookup
                  59. Smith TC, Male MJ, Harper AL, Kroeger JS, Tinkler GP, Moritz ED, Capuano AW, Herwaldt LA, Diekema DJ. Methicillin-resistant Staphylococcus aureus (MRSA) strain ST398 is present in midwestern U.S. swine and swine workers. PLoS One 2009;4(1):e4258.
                    doi: 10.1371/journal.pone.0004258pubmed: 19145257google scholar: lookup
                  60. Walther B, Monecke S, Ruscher C, Friedrich AW, Ehricht R, Slickers P, Soba A, Wleklinski CG, Wieler LH, Lübke-Becker A. Comparative molecular analysis substantiates zoonotic potential of equine methicillin-resistant Staphylococcus aureus. J Clin Microbiol 2009 Mar;47(3):704-10.
                    doi: 10.1128/JCM.01626-08pubmed: 19109463google scholar: lookup
                  61. Burton S, Reid-Smith R, McClure JT, Weese JS. Staphylococcus aureus colonization in healthy horses in Atlantic Canada. Can Vet J 2008 Aug;49(8):797-9.
                    pubmed: 18978975
                  62. van Loo I, Huijsdens X, Tiemersma E, de Neeling A, van de Sande-Bruinsma N, Beaujean D, Voss A, Kluytmans J. Emergence of methicillin-resistant Staphylococcus aureus of animal origin in humans. Emerg Infect Dis 2007 Dec;13(12):1834-9.
                    doi: 10.3201/eid1312.070384pubmed: 18258032google scholar: lookup
                  63. Weese JS, Lefebvre SL. Risk factors for methicillin-resistant Staphylococcus aureus colonization in horses admitted to a veterinary teaching hospital. Can Vet J 2007 Sep;48(9):921-6.
                    pubmed: 17966332
                  64. Hanselman BA, Kruth SA, Rousseau J, Low DE, Willey BM, McGeer A, Weese JS. Methicillin-resistant Staphylococcus aureus colonization in veterinary personnel. Emerg Infect Dis 2006 Dec;12(12):1933-8.
                    doi: 10.3201/eid1212.060231pubmed: 17326947google scholar: lookup
                  65. Huijsdens XW, van Dijke BJ, Spalburg E, van Santen-Verheuvel MG, Heck ME, Pluister GN, Voss A, Wannet WJ, de Neeling AJ. Community-acquired MRSA and pig-farming. Ann Clin Microbiol Antimicrob 2006 Nov 10;5:26.
                    doi: 10.1186/1476-0711-5-26pubmed: 17096847google scholar: lookup
                  66. Schnellmann C, Gerber V, Rossano A, Jaquier V, Panchaud Y, Doherr MG, Thomann A, Straub R, Perreten V. Presence of new mecA and mph(C) variants conferring antibiotic resistance in Staphylococcus spp. isolated from the skin of horses before and after clinic admission. J Clin Microbiol 2006 Dec;44(12):4444-54.
                    doi: 10.1128/JCM.00868-06pubmed: 17005735google scholar: lookup
                  67. Bemis DA, Jones RD, Hiatt LE, Ofori ED, Rohrbach BW, Frank LA, Kania SA. Comparison of tests to detect oxacillin resistance in Staphylococcus intermedius, Staphylococcus schleiferi, and Staphylococcus aureus isolates from canine hosts. J Clin Microbiol 2006 Sep;44(9):3374-6.
                    doi: 10.1128/JCM.01336-06pubmed: 16954277google scholar: lookup
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