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Mr imaging features of surgically induced core lesions in the equine superficial digital flexor tendon.

Abstract: Tendon injuries are common in athletic humans and horses. Ultrasonography is the diagnostic method of choice in horses with tendon injuries but there is increasing application of magnetic resonance (MR) imaging to monitor and follow-up tendon healing. A core lesion was created in the superficial digital flexor tendon (SDFT) of each forelimb of four horses. One of the four horses was euthanized at 2, 4, 8, and 12 weeks after creation of the lesion. MR examinations of the SDFT were performed immediately post mortem in a 1.5 T Siemens Symphony magnet and compared with histologic findings. Measurements from the MR images were also compared to ultrasonographic measurements available from the same lesions. Tendon lesions appeared as well-circumscribed hyperintensities in the core of the SDFT on all pulse sequences. Lesions were most conspicuous on fat-suppressed fast low angle shot (FLASH) sequences and least conspicuous on T2 transverse dual turbo spin echo (T2 TSE) sequences. The signal-difference-to-noise ratio decreased with the age of the lesion in all sequences in this study. Twelve-week-old lesions were not visible on T2 TSE images but in all other sequences the lesion remained hyperintense. The lesion volume and maximum cross-sectional area of core lesions were significantly smaller in T2 TSE images than in other MR sequences. The lesion volume and maximum cross-sectional area of core lesions were significantly larger in proton density, T1, and FLASH sequences and significantly smaller in T2 sequences than when measured from ultrasonographic images. Through comparison between sequences, MR imaging may be able to provide information on various stages of tendon healing.
Publication Date: 2010-05-18 PubMed ID: 20469549DOI: 10.1111/j.1740-8261.2009.01660.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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The research investigates the role of magnetic resonance imaging (MRI) in diagnosing and following up on tendon healing in horses, after surgically inducing a lesion in the superficial digital flexor tendon (SDFT). The study also compares the effectiveness of MRI to that of ultrasonography for the same purpose.

Introduction to the Study

  • The scientists involved in this research study were examining the effects of surgically induced lesions on the superficial digital flexor tendons of four horses.
  • These tendon injuries are fairly common in both athletic humans and horses.
  • The study was focused on the use of MRI as a method for diagnosing these injuries and monitoring their healing process.

Procedure of the Study

  • In order to carry out the study, one of the four horses was euthanized at different intervals – 2, 4, 8 and 12 weeks after the tendon lesion had been created.
  • Post mortem MR examinations were performed on the SDFT using a 1.5 T Siemens Symphony magnet.
  • The observations gleaned from these procedures were then compared with histologic observations and measurements.
  • These measurements were also compared to those obtained from the same lesions through ultrasonographic procedures.

Findings of the Study

  • The tendon lesions that were surgically created were identified as well-circumscribed hyperintensities in the core of the SDFT on all pulse sequences during the MR examinations.
  • The lesions were most conspicuous on fat-suppressed fast low angle shot (FLASH) sequences and least conspicuous on T2 transverse dual turbo spin echo (T2 TSE) sequences.
  • The signal-difference-to-noise ratio recorded from these lesions tended to decrease as the age of the lesion increased. As such, the 12-week-old lesions were not visible on T2 TSE images.
  • Conversely, lesions remained hyperintense in all other MR sequences, despite their age.
  • Measurements of lesion volume and maximum cross-sectional area were found to be significantly smaller in T2 TSE images in comparison to other MR sequences.
  • Similarly, these measurements were significantly larger in proton density, T1, and FLASH sequences and exceedingly smaller in T2 sequences when compared to measurements gleaned from ultrasonographic images.

Conclusion of the Study

  • The authors concluded that magnetic resonance imaging can offer valuable information about various stages of tendon healing, given the contrast between sequence images.
  • The study suggests that MRI can provide a more comprehensive picture of tendon injuries and may be a viable alternative or addition to ultrasonography for diagnostic and follow-up purposes.

Cite This Article

APA
Schramme M, Kerekes Z, Hunter S, Labens R. (2010). Mr imaging features of surgically induced core lesions in the equine superficial digital flexor tendon. Vet Radiol Ultrasound, 51(3), 280-287. https://doi.org/10.1111/j.1740-8261.2009.01660.x

Publication

ISSN: 1058-8183
NlmUniqueID: 9209635
Country: England
Language: English
Volume: 51
Issue: 3
Pages: 280-287

Researcher Affiliations

Schramme, Michael
  • College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA. michael_schramme@ncsu.edu
Kerekes, Zoltan
    Hunter, Stuart
      Labens, Raphael

        MeSH Terms

        • Animals
        • Forelimb / injuries
        • Horses / injuries
        • Magnetic Resonance Imaging / veterinary
        • Tendon Injuries / diagnosis
        • Tendon Injuries / veterinary
        • Tendons / pathology

        Citations

        This article has been cited 7 times.
        1. Doll CU, Bohner M, Berner D, Buettner K, Horstmeier C, Winter K, Burk J. Approaches to standardising the magnetic resonance image analysis of equine tendon lesions. Vet Rec Open 2023 Jun;10(1):e257.
          doi: 10.1002/vro2.57pubmed: 36846276google scholar: lookup
        2. Doll CU, von Pueckler K, Offhaus J, Berner D, Burk J. Characterization of Equine Chronic Tendon Lesions in Low- and High-Field Magnetic Resonance Imaging. Vet Sci 2022 Jun 15;9(6).
          doi: 10.3390/vetsci9060297pubmed: 35737349google scholar: lookup
        3. Pluim M, Martens A, Vanderperren K, van Weeren R, Oosterlinck M, Dewulf J, Kichouh M, Van Thielen B, Koene MHW, Luciani A, Plancke L, Delesalle C. High-Power Laser Therapy Improves Healing of the Equine Suspensory Branch in a Standardized Lesion Model. Front Vet Sci 2020;7:600.
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        4. Ge XJ, Zhang L, Xiang G, Hu YC, Lun DX. Cross-Sectional Area Measurement Techniques of Soft Tissue: A Literature Review. Orthop Surg 2020 Dec;12(6):1547-1566.
          doi: 10.1111/os.12757pubmed: 32930465google scholar: lookup
        5. Wagner JR, Taguchi T, Cho JY, Charavaryamath C, Griffon DJ. Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats. J Vis Exp 2018 Mar 30;(133).
          doi: 10.3791/56810pubmed: 29658926google scholar: lookup
        6. Scharf A, Holmes SP, Thoresen M, Mumaw J, Stumpf A, Peroni J. MRI-Based Assessment of Intralesional Delivery of Bone Marrow-Derived Mesenchymal Stem Cells in a Model of Equine Tendonitis. Stem Cells Int 2016;2016:8610964.
          doi: 10.1155/2016/8610964pubmed: 27746821google scholar: lookup
        7. Scharf A, Acutt E, Bills K, Werpy N. Magnetic resonance imaging for diagnosing and managing deep digital flexor tendinopathy in equine athletes: Insights, advances and future directions. Equine Vet J 2025 Sep;57(5):1183-1203.
          doi: 10.1111/evj.14508pubmed: 40314097google scholar: lookup