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Veterinary and human toxicology2000; 42(3); 166-167;

Mushroom toxicity in a horse with meningioangiomatosis.

Abstract: We describe a fatal case of mushroom intoxication in an 18-y-o horse presumably due to Amanita verna. Horses are normally regarded as too fastidious to eat the ill-flavored toadstools. In this case, the horse had a rare benign brain tumor, meningioangiomatosis, which may have altered the horse's normal eating behavior resulting in consumption of the mushrooms.
Publication Date: 2000-06-06 PubMed ID: 10839323
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Summary

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The research paper discusses a unique case where a horse died from consuming toxic mushrooms, presumably due to a rare brain tumor that might have caused a change in its eating habits.

Introduction

  • The study focuses on an unusual incident of mushroom poisoning in an 18-year-old horse, apparently caused by the Amanita verna mushroom.
  • Typically, horses are seen as too discerning to consume distastefully flavored toadstools. However, the horse in focus here exhibited a change in eating habits, attributed to a specific kind of benign brain tumor.

About the Brain Tumor

  • The horse was diagnosed with a rare type of benign brain tumor known as meningioangiomatosis.
  • The presence of this brain tumor is assumed to be the key factor that led to the alteration in the horse’s normal eating behavior, driving it to ingest mushrooms it otherwise would not.

Investigation and Findings

  • The researchers set out to understand the connection between the brain tumor and the change in feeding habit, investigating whether it truly led the horse to consume toxic mushrooms, thus causing its untimely death.
  • The paper discusses the findings of their exploration, resting on the theory that the meningioangiomatosis steered the horse to eat the poisonous Amanita verna.

Significance

  • The findings of such research are significant as they add to the understanding of animal behavior, particularly how it can be impacted by illnesses such as brain tumors.
  • This could help in better diagnosing and predicting animal eating habits, consequently preventing similar incidents of poisoning in the future.

Cite This Article

APA
Frazier K, Liggett A, Hines M, Styer E. (2000). Mushroom toxicity in a horse with meningioangiomatosis. Vet Hum Toxicol, 42(3), 166-167.

Publication

ISSN: 0145-6296
NlmUniqueID: 7704194
Country: United States
Language: English
Volume: 42
Issue: 3
Pages: 166-167

Researcher Affiliations

Frazier, K
  • Veterinary Diagnostic and Investigational Laboratory, College of Veterinary Medicine, University of Georgia, Tifton 31793, USA.
Liggett, A
    Hines, M
      Styer, E

        MeSH Terms

        • Amanita / isolation & purification
        • Angiomatosis / complications
        • Angiomatosis / veterinary
        • Animals
        • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
        • Behavior, Animal
        • Central Nervous System Diseases / complications
        • Central Nervous System Diseases / veterinary
        • Cephalexin / therapeutic use
        • Cephalosporins / therapeutic use
        • Clonixin / analogs & derivatives
        • Clonixin / therapeutic use
        • Dexamethasone / therapeutic use
        • Fatal Outcome
        • Feeding Behavior
        • Female
        • Gastric Lavage / veterinary
        • Glucocorticoids / therapeutic use
        • Horse Diseases / pathology
        • Horse Diseases / therapy
        • Horses
        • Liver / pathology
        • Lung / pathology
        • Meninges
        • Mushroom Poisoning / complications
        • Mushroom Poisoning / therapy
        • Mushroom Poisoning / veterinary

        Citations

        This article has been cited 4 times.
        1. Vetter J. Amanitins: The Most Poisonous Molecules of the Fungal World. Molecules 2023 Aug 7;28(15).
          doi: 10.3390/molecules28155932pubmed: 37570902google scholar: lookup
        2. Corbett MP, Kopec BL, Kent M, Rissi DR. Encephalic meningioangiomatosis in a cat. J Vet Diagn Invest 2022 Sep;34(5):889-893.
          doi: 10.1177/10406387221110912pubmed: 35833693google scholar: lookup
        3. Mittelman NS, Engiles JB, Murphy L, Vudathala D, Johnson AL. Presumptive Iatrogenic Microcystin-Associated Liver Failure and Encephalopathy in a Holsteiner Gelding. J Vet Intern Med 2016 Sep;30(5):1747-1751.
          doi: 10.1111/jvim.14571pubmed: 27611818google scholar: lookup
        4. Gunovska H, Degl'Innocenti S, Targett M, Carrera I, Gomes SA. Case Report: Infiltrative multifocal meningioangiomatosis affecting the spinal cord of a young Labrador Retriever. Front Vet Sci 2025;12:1580306.
          doi: 10.3389/fvets.2025.1580306pubmed: 40557270google scholar: lookup