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Parasite epidemiology and control2020; 10; e00158; doi: 10.1016/j.parepi.2020.e00158

Nationwide serological surveillance of non-tsetse-transmitted horse trypanosomoses in Mongolia.

Abstract: In Mongolia, horses play important roles, not only in livestock production, but also in terms of culture, tradition, and Mongolian beliefs. Although the presence of non-tsetse-transmitted horse trypanosomoses, which are caused by infections with (surra) and (dourine), has been reported in the country, whether there is a nationwide epidemic of these infectious diseases is unknown. In the present study, a nationwide surveillance of horse trypanosomoses was performed. The sample sizes for each province, the whole country, and male and female horses were, respectively, 96, 2,400, and 316 and 306. In total, 3,641 samples of horse sera were collected by simple random sampling. The rTeGM6-4r-based ELISA, which was applied for surra against cattle and water buffalo and dourine against horse, revealed that the overall sero-prevalence of the diseases in Mongolia was 4.8%. Among them, high sero-prevalences were observed in the central provinces (5.2-11.0%,  < 0.05) of the country. The sero-prevalence was significantly higher in females than in males (6.0% and 4.0%,  < 0.05, respectively) and in non-castrated males (8.4%,  < 0.01) compared with castrated males (3.0%). These results suggested that currently, horse trypanosomoses are a nationwide endemic problem in Mongolia. Knowledge of the nationwide endemic status of non-tsetse-transmitted horse trypanosomoses in Mongolia will be useful to prevent these diseases.
© 2020 The Authors.
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Publication Date: 2020-06-25 PubMed ID: 32642568PubMed Central: PMC7334808DOI: 10.1016/j.parepi.2020.e00158Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research focuses on a nationwide investigation of non-tsetse-transmitted horse trypanosomoses (disease caused by parasitic protozoans) in Mongolia. The results revealed a 4.8% prevalence of the disease in the country, particularly higher in female horses and non-castrated male horses.

Objective and Methodology

  • The aim of this research was to determine the national spread of non-tsetse-transmitted horse trypanosomoses in Mongolia — a disease caused by parasite infection. In Mongolia, horses hold significant cultural and traditional importance, thus making this a critical study.
  • The study carried out nationwide surveillance of horse trypanosomoses by collecting samples of horse sera. The sample size consisted of 96 samples from each province, 2,400 samples nationally, and 316 and 306 from male and female horses, respectively. The entire collection amounted to 3,641 samples, which were acquired through simple random sampling.

Results and Analysis

  • The samples were tested using the rTeGM6-4r-based ELISA, typically used to detect surra (a form of trypanosomosis) in cattle and water buffalo and dourine (another form of trypanosomosis) in horses.
  • The tests revealed an overall sero-prevalence of trypanosomoses in Mongolia at 4.8%.
  • The central provinces had a notably high sero-prevalence ranging from 5.2% to 11.0%.
  • When segregated by sex, the sero-prevalence was significantly higher in female horses (6.0%) compared to male horses (4.0%). Furthermore, non-castrated male horses had an even higher prevalence rate of 8.4% when compared to castrated male horses (3.0%).

Conclusion and Significance

  • Given the results, the study suggested that non-tsetse-transmitted horse trypanosomoses constitute a nationwide problem in Mongolia, affecting a notable percentage of the horse population, especially in the central provinces.
  • An understanding and awareness of this nationwide endemic can help manipulate effective disease prevention strategies, which are vital considering the cultural and practical significance of horses in Mongolia.

Cite This Article

APA
Mizushima D, Amgalanbaatar T, Davaasuren B, Kayano M, Naransatsral S, Myagmarsuren P, Otgonsuren D, Enkhtaivan B, Davkharbayar B, Mungun-Ochir B, Baatarjargal P, Nyamdolgor U, Soyolmaa G, Altanchimeg A, Zoljargal M, Nguyen TT, Battsetseg B, Battur B, Inoue N, Yokoyama N, Suganuma K. (2020). Nationwide serological surveillance of non-tsetse-transmitted horse trypanosomoses in Mongolia. Parasite Epidemiol Control, 10, e00158. https://doi.org/10.1016/j.parepi.2020.e00158

Publication

Parasite epidemiology and control
ISSN: 2405-6731
NlmUniqueID: 101687137
Country: Netherlands
Language: English
Volume: 10
Pages: e00158
PII: e00158

Researcher Affiliations

Mizushima, Daiki
  • National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
  • Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan.
Amgalanbaatar, Tovuu
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Davaasuren, Batdorj
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Kayano, Mitsunori
  • Research Center for Global Agromedicine, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
Naransatsral, Sandagdorj
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Myagmarsuren, Punsantsogvoo
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Otgonsuren, Davaajav
  • National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Enkhtaivan, Batsaikhan
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Davkharbayar, Batbold
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Mungun-Ochir, Bayasgalan
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Baatarjargal, Purevdorj
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Nyamdolgor, Uranbileg
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Soyolmaa, Gurdorj
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Altanchimeg, Adilbish
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Zoljargal, Myagmar
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Nguyen, Thu-Thuy
  • National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
Battsetseg, Badgar
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Battur, Banzragch
  • Institute of Veterinary Medicine, Laboratory of Molecular Genetics, Mongolian University of Life Sciences, Zaisan 17024, Ulaanbaatar, Mongolia.
Inoue, Noboru
  • Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
Yokoyama, Naoaki
  • National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
Suganuma, Keisuke
  • National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.
  • Research Center for Global Agromedicine, Obihiro University of Agriculture and Veterinary Medicine, Inada, Obihiro, Hokkaido 080-8555, Japan.

Conflict of Interest Statement

The authors declare no competing interests in association with this study.

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Citations

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