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Home / Equine Research Bank / J Am Vet Med Assoc / Neoplasms of Equidae.
Journal of the American Veterinary Medical Association1977; 170(2); 150-152;

Neoplasms of Equidae.

Abstract: In a retrospective study of neoplasms in Equidae pre;ented to the Animal Disease Diagnostic Laboratory, Purdue University, from Jan 1, 1970, to Dec 31, 1974, data were compiled on numbers and anatomic sites of neoplasms as well as on age, sex, and breed of subjects from which the neoplasms were taken. During this 5-year period, 21 neoplasms were diagnosed from 687 equine necropsies (3.1%) and 215 from 635 biopsies (33.9%), totaling 236 neoplasms from 1,322 cases (17.9%). The most common neoplasms were sarcoids (43.6%) and squamous cell carcinomas (24.6%). Papillomas (5.5%), nerve sheath tumors (4.2%), melanomas (3.8%), lipomas (3.0%), granulosa cell tumors (2.5%), fibromas (2.1%), cholesteatomas (1.3%), and lymphosarcomas (1.3%) were less common.
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Publication Date: 1977-01-15 PubMed ID: 576219
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research paper is a review of a study conducted on neoplasms (cancerous tumors) in Equidae (a family of mammals that includes horses and zebras) at Purdue University’s Animal Disease Diagnostic Laboratory from 1970 to 1974. The study examines the frequency, type, and location of these tumors as well as the age, breed, and sex of the subjects.

Summary of the Study

The research conducted was a retrospective study, examining previous cases of neoplasms or cancerous tumors in the Equidae family. The cases were pulled from the Animal Disease Diagnostic Laboratory at Purdue University during a five-year period from 1970 to 1974.

  • The study sought to examine the number of neoplasms, their anatomic locations, and the related information about the animals. Data like the animal’s age, sex, and breed were all compiled for an in-depth analysis.

Findings of the Research

The findings were based on 1322 cases.

  • During the five-year study, of the 687 equine (horse) necropsies (post-mortem examinations) conducted, 21 neoplasms were found, representing 3.1% of the cases.
  • On the other hand, of the 635 biopsies conducted, 215 neoplasms were discovered, a significantly higher percentage at 33.9%.
  • In total, the study recorded 236 neoplasms from 1322 cases, an overall percentage of 17.9%.

Common Types of Neoplasms

The most common neoplasms diagnosed in these Equidae subjects were sarcoids and squamous cell carcinomas.

  • Sarcoids, making up 43.6% of the neoplasms, are a type of skin tumor that is the most common form of cancer in horses.
  • Squamous cell carcinomas, representing 24.6% of the neoplasms, are a type of skin cancer that arises from the squamous cells that make up the outer layer of the skin.

Less Frequent Types of Neoplasms

The study also found a range of less common neoplasms.

  • Papillomas (5.5%) are a type of benign tumor that causes wart-like growths.
  • Nerve sheath tumors (4.2%) are tumors that develop in the protective lining of the nerves.
  • Melanomas (3.8%) are a type of tumor often associated with pigmented cells.
  • Lipomas (3%) are benign tumors made from fatty tissues.
  • Granulosa cell tumors (2.5%) are a type of ovarian tumor.
  • Fibromas (2.1%) are benign tumors composed of fibrous or connective tissue.
  • Cholesteatomas (1.3%) and lymphosarcomas (1.3%) were the least common of the neoplasms.

Cite This Article

APA
Sundberg JP, Burnstein T, Page EH, Kirkham WW, Robinson FR. (1977). Neoplasms of Equidae. J Am Vet Med Assoc, 170(2), 150-152.

Publication

Journal of the American Veterinary Medical Association
ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 170
Issue: 2
Pages: 150-152

Researcher Affiliations

Sundberg, J P
    Burnstein, T
      Page, E H
        Kirkham, W W
          Robinson, F R

            MeSH Terms

            • Animals
            • Carcinoma, Squamous Cell / epidemiology
            • Carcinoma, Squamous Cell / veterinary
            • Cholesteatoma / epidemiology
            • Cholesteatoma / veterinary
            • Female
            • Horse Diseases / epidemiology
            • Horses
            • Lymphoma, Non-Hodgkin / epidemiology
            • Lymphoma, Non-Hodgkin / veterinary
            • Male
            • Melanoma / epidemiology
            • Melanoma / veterinary
            • Neoplasms / veterinary
            • Papilloma / epidemiology
            • Papilloma / veterinary
            • Perissodactyla
            • Skin Neoplasms / epidemiology
            • Skin Neoplasms / veterinary

            Citations

            This article has been cited 22 times.
            1. Quatember H, Nell B, Richter B, Rigler D, Dolezal M, Sykora S, Wallner B. Studying the Impact of the DDB2 T338M Missense Mutation on the Development of Equine Squamous Cell Carcinoma and Sarcoid. Animals (Basel) 2025 Mar 22;15(7).
              doi: 10.3390/ani15070911pubmed: 40218305google scholar: lookup
            2. Zscherpe P, Kalbitz J, Weber LA, Paschke R, Mäder K, von Rechenberg B, Cavalleri JV, Meißner J, Klein K. Potent drug delivery enhancement of betulinic acid and NVX-207 into equine skin in vitro - a comparison between a novel oxygen flow-assisted transdermal application device and microemulsion gels. BMC Vet Res 2024 May 16;20(1):202.
              doi: 10.1186/s12917-024-04064-1pubmed: 38755639google scholar: lookup
            3. Tinkler SH, Villa L, Manfredi MT, Walshe N, Jahns H. First report of Besnoitia bennetti in Irish donkeys: an emerging parasitic disease in Europe. Ir Vet J 2024 Feb 14;77(1):2.
              doi: 10.1186/s13620-024-00263-2pubmed: 38355717google scholar: lookup
            4. Fesmire CC, Peal B, Ruff J, Moyer E, McParland TJ, Derks K, O'Neil E, Emke C, Johnson B, Ghosh S, Petrella RA, DeWitt MR, Prange T, Fogle C, Sano MB. Investigation of integrated time nanosecond pulse irreversible electroporation against spontaneous equine melanoma. Front Vet Sci 2024;11:1232650.
              doi: 10.3389/fvets.2024.1232650pubmed: 38352036google scholar: lookup
            5. Kashani-Carver A, O'Halloran C, Scurrell E, Featherstone H, de Freitas FF, Lowe R. Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom. Open Vet J 2023 Oct;13(10):1366-1378.
              doi: 10.5455/OVJ.2023.v13.i10.17pubmed: 38027397google scholar: lookup
            6. Tommasa SD, Roth SP, Triebe T, Brehm W, Lohmann KL, Stöckle SD. Successful intra-abdominal resection of a 24 kg ovarian granulosa cell tumor in a Warmblood mare. Open Vet J 2023 Sep;13(9):1212-1218.
              doi: 10.5455/OVJ.2023.v13.i9.17pubmed: 37842112google scholar: lookup
            7. Straticò P, Hattab J, Guerri G, Carluccio A, Bandera L, Celani G, Marruchella G, Varasano V, Petrizzi L. Behavioral Disorders in Mares with Ovarian Disorders, Outcome after Laparoscopic Ovariectomy: A Case Series. Vet Sci 2023 Jul 25;10(8).
              doi: 10.3390/vetsci10080483pubmed: 37624270google scholar: lookup
            8. Munday JS, Knight CG, Luff JA. Papillomaviral skin diseases of humans, dogs, cats and horses: A comparative review. Part 1: Papillomavirus biology and hyperplastic lesions. Vet J 2022 Oct;288:105897.
              doi: 10.1016/j.tvjl.2022.105897pubmed: 36150643google scholar: lookup
            9. Tesena P, Kingkaw A, Vongsangnak W, Pitikarn S, Phaonakrop N, Roytrakul S, Kovitvadhi A. Preliminary Study: Proteomic Profiling Uncovers Potential Proteins for Biomonitoring Equine Melanocytic Neoplasm. Animals (Basel) 2021 Jun 27;11(7).
              doi: 10.3390/ani11071913pubmed: 34199079google scholar: lookup
            10. Weber LA, Meißner J, Delarocque J, Kalbitz J, Feige K, Kietzmann M, Michaelis A, Paschke R, Michael J, Pratscher B, Cavalleri JV. Betulinic acid shows anticancer activity against equine melanoma cells and permeates isolated equine skin in vitro. BMC Vet Res 2020 Feb 5;16(1):44.
              doi: 10.1186/s12917-020-2262-5pubmed: 32024502google scholar: lookup
            11. Lloyd-Edwards RA, Willems DS, Beukers M, van den Brom-Spierenburg A, Vernooij JCM, Veraa S. Presumed cholesterinic granulomas detected on CT in horses are associated with increased lateral ventricle height and age. Vet Radiol Ultrasound 2020 May;61(3):269-278.
              doi: 10.1111/vru.12847pubmed: 32020759google scholar: lookup
            12. Ludwig EK, Byron CR, Lahmers KK, Santos MP. Frontal and caudal maxillary sinus lipoma in a horse. Can Vet J 2017 May;58(5):503-507.
              pubmed: 28487595
            13. Lunardi M, de Alcântara BK, Otonel RA, Rodrigues WB, Alfieri AF, Alfieri AA. Bovine papillomavirus type 13 DNA in equine sarcoids. J Clin Microbiol 2013 Jul;51(7):2167-71.
              doi: 10.1128/JCM.00371-13pubmed: 23637294google scholar: lookup
            14. Reid N. Squamous cell carcinoma and suspect peripheral nerve sheath tumor in a 10-year-old Paint horse. Can Vet J 2009 Nov;50(11):1195-7.
              pubmed: 20119546
            15. McMullen RJ, Clode AB, Pandiri AK, Malarkey DE, Michau TM, Gilger BC. Epibulbar melanoma in a foal. Vet Ophthalmol 2008 Sep;11 Suppl 1(Suppl 1):44-50.
              doi: 10.1111/j.1463-5224.2008.00637.xpubmed: 19046269google scholar: lookup
            16. Lefebvre R, Theoret C, Doré M, Girard C, Laverty S, Vaillancourt D. Ovarian teratoma and endometritis in a mare. Can Vet J 2005 Nov;46(11):1029-33.
              pubmed: 16363331
            17. Spoormakers TJ, Klein WR, Jacobs JJ, Van Den Ingh TS, Koten JW, Den Otter W. Comparison of the efficacy of local treatment of equine sarcoids with IL-2 or cisplatin/IL-2. Cancer Immunol Immunother 2003 Mar;52(3):179-84.
              doi: 10.1007/s00262-002-0369-0pubmed: 12649747google scholar: lookup
            18. Carstanjen B, Jordan P, Lepage OM. Carbon dioxide laser as a surgical instrument for sarcoid therapy--a retrospective study on 60 cases. Can Vet J 1997 Dec;38(12):773-6.
              pubmed: 9426943
            19. Broström H. Equine sarcoids. A clinical and epidemiological study in relation to equine leucocyte antigens (ELA). Acta Vet Scand 1995;36(2):223-36.
              doi: 10.1186/BF03547691pubmed: 7484549google scholar: lookup
            20. Bosu WT, Van Camp SC, Miller RB, Owen RR. Ovarian disorders: clinical and morphological observations in 30 mares. Can Vet J 1982 Jan;23(1):6-14.
              pubmed: 7066859
            21. Pascoe PJ. Colic in a mare caused by a colonic neurofibroma. Can Vet J 1982 Jan;23(1):24-7.
              pubmed: 7066855
            22. Klein WR, Bras GE, Misdorp W, Steerenberg PA, de Jong WH, Tiesjema RH, Kersjes AW, Ruitenberg EJ. Equine sarcoid: BCG immunotherapy compared to cryosurgery in a prospective randomised clinical trial. Cancer Immunol Immunother 1986;21(2):133-40.
              doi: 10.1007/BF00199861pubmed: 3633215google scholar: lookup
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