Objective evaluation of two deworming regimens in young Thoroughbreds using parasitological and performance parameters.
Abstract: Parasitic helminths of equids are capable of causing ill-thrift, clinical disease, and death. Although young horses are the most susceptible to parasitic disease and are the most intensively treated cohort, deworming regimens are rarely evaluated within this age group. This study objectively evaluated the impact of deworming regimen on fecal egg counts (FECs), growth rates, and body-condition scores in young Thoroughbreds. Forty-eight Thoroughbred foals from three central Kentucky farms were randomly allocated to two treatment groups: an interval dose program receiving bi-monthly rotations of pyrantel pamoate and ivermectin and a daily deworming group receiving daily rations of pyrantel tartrate feed additive throughout the study, oxibendazole at two months of age, and moxidectin treatments at 9.5 and 16.5 months of age. Pre- and post-treatment eggs per gram of feces (EPGs) of Parascaris spp. and strongyle family parasites, gel/paste dewormer efficacies, and monthly weights and body condition scores were collected. Ascarid and strongyle FECs were not significantly different between groups but were significantly influenced by horse age with strongyle counts continually increasing and ascarid counts peaking at 4.5 months of age. Reduced strongyle efficacies of ivermectin and moxidectin were observed on two farms with consistently low pyrantel pamoate efficacies on all three farms. Ivermectin also exhibited reduced ascarid efficacy. Average daily gain did not differ significantly between groups and was only significantly influenced by age, mirroring average daily gain reference data for Kentucky Thoroughbreds born in 2013. Body condition scores also did not differ between groups, remaining in the optimal range (5-6) for the duration of the study. Management practices resulting in growth rates matching the reference data and in optimal body condition scores compensate for the negative impacts of parasitism even in cases of reduced drug efficacy. Performance parameters can provide useful information in cases of suboptimal parasite control.
Copyright © 2016 Elsevier B.V. All rights reserved.
Publication Date: 2016-03-22 PubMed ID: 27084476DOI: 10.1016/j.vetpar.2016.03.018Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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This study evaluates the effects of two different deworming treatments for young Thoroughbred horses, examining the impact on the horse’s growth rates, fecal egg counts, and body condition. Findings indicate that while the type of treatment did not have a significant effect, the age of the horse did, and there were concerns about reduced effectiveness with some deworming drugs. However, good management practices mitigated the negative effects of parasitism on the horses.
Research Design and Methodology
- The researchers used 48 Thoroughbred foals from three farms in central Kentucky.
- The foals were randomly divided into two treatment groups. One group was subjected to an interval dose program, while the other group received daily deworming.
- Both pre- and post-treatment effectively assessed the impact of the deworming formula in the issues of strongyle and ascarid parasites and their impact on the horse’s health.
Key Findings
- Fecal egg counts for ascarid and strongyle parasites did not significantly differ between the two treatment groups.
- Differences in the fecal egg counts were significantly influenced by the age of the horse however. Ascarid counts peaked at 4.5 months of age, while strongyle counts continuously increased.
- Reduced efficacy of certain deworming drugs, including ivermectin and moxidectin for strongyles and ivermectin for ascarids, was observed.
- The average daily gain or growth rate was not significantly affected by the deworming treatment, but was significantly influenced by the age of the horse. This mirrored previous data on Kentucky Thoroughbreds born in 2013.
- Body condition scores remained in the optimal range (5-6) for both treatment groups throughout the study.
Implication and Conclusion
- The study showed that certain deworming drugs might not be as effective as believed. However, with good farm management practices, growth rates could be maintained and body condition scores could remain in the optimal range.
- The findings also suggested that the age of the horse had a significant effect, indicating a potential need for age-specific deworming treatments.
- This study provided insight into how performance parameters can be useful for assessing parasite control, especially when drug efficacy is not optimal.
Cite This Article
APA
Bellaw JL, Pagan J, Cadell S, Phethean E, Donecker JM, Nielsen MK.
(2016).
Objective evaluation of two deworming regimens in young Thoroughbreds using parasitological and performance parameters.
Vet Parasitol, 221, 69-75.
https://doi.org/10.1016/j.vetpar.2016.03.018 Publication
Researcher Affiliations
- M. H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, USA. Electronic address: jbe244@uky.edu.
- Kentucky Equine Research, Versailles, KY, USA.
- Hallway Feeds, Lexington, KY, USA.
- Kentucky Equine Research, Versailles, KY, USA.
- Zoetis, Outcomes Research, Reidsville, NC, USA.
- M. H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, USA.
MeSH Terms
- Age Factors
- Animals
- Anthelmintics / administration & dosage
- Anthelmintics / pharmacology
- Ascaridida Infections / drug therapy
- Ascaridida Infections / veterinary
- Ascaridoidea
- Feces / parasitology
- Horse Diseases / drug therapy
- Horses
- Parasite Egg Count / veterinary
- Random Allocation
- Treatment Outcome
- Weight Gain / drug effects
Citations
This article has been cited 6 times.- Elghryani N, McOwan T, Mincher C, Duggan V, de Waal T. Estimating the Prevalence and Factors Affecting the Shedding of Helminth Eggs in Irish Equine Populations. Animals (Basel) 2023 Feb 7;13(4).
- Cain JL, Nielsen MK. The equine ascarids: resuscitating historic model organisms for modern purposes. Parasitol Res 2022 Oct;121(10):2775-2791.
- Scala A, Tamponi C, Sanna G, Predieri G, Dessì G, Sedda G, Buono F, Cappai MG, Veneziano V, Varcasia A. Gastrointestinal Strongyles Egg Excretion in Relation to Age, Gender, and Management of Horses in Italy. Animals (Basel) 2020 Dec 3;10(12).
- Jenkins E, Backwell AL, Bellaw J, Colpitts J, Liboiron A, McRuer D, Medill S, Parker S, Shury T, Smith M, Tschritter C, Wagner B, Poissant J, McLoughlin P. Not playing by the rules: Unusual patterns in the epidemiology of parasites in a natural population of feral horses (Equus caballus) on Sable Island, Canada. Int J Parasitol Parasites Wildl 2020 Apr;11:183-190.
- Malek IA, Baharudin F, Peng TL, Sabri J. Development and Survivability of The Free-Living Stage Larvae of Equine Strongyles in Different Environments and Soil Types. Trop Life Sci Res 2025 Oct;36(3):101-120.
- Buono F, Veneziano V, Veronesi F, Molento MB. Horse and donkey parasitology: differences and analogies for a correct diagnostic and management of major helminth infections. Parasitology 2023 Oct;150(12):1119-1138.
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