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Veterinary medicine and science2021; 7(6); 2209-2218; doi: 10.1002/vms3.607

Outcomes following single, caudally based bilateral versus unilateral frontonasal sinusotomy for treatment of equine paranasal sinus disease.

Abstract: Bilateral sinus disease is relatively uncommon in horses, accounting for 3%-4.5% of horses with sinonasal disease, but may require bilateral paranasal surgery for complete resolution. Complications and recurrence following bilateral sinusotomy have not been reported or compared to those following unilateral procedures. To describe clinical features and outcomes in horses undergoing standing single, caudally based bilateral frontonasal sinusotomy compared to unilateral frontonasal surgery. Records of horses (n = 37) undergoing surgical treatment for sinus disease (five bilateral, 32 unilateral) were retrospectively reviewed (2010-2017) for signalment, presenting complaint, duration of signs preoperatively, diagnostic imaging, treatments administered, duration hospitalization, complications, and owner satisfaction with the procedure. Mann-Whitney testing was used to compare age, duration of hospitalization, and follow-up time in horses undergoing unilateral or bilateral procedures. Fisher's exact testing was used to determine if sex predilection was present for unilateral or bilateral disease. Survival time and time to recurrence were compared by Kaplan-Meier survival curves and log-rank curve comparison testing. Significance was assessed at p < 0.05. Length of signs prior to admission did not differ between horses with unilateral and bilateral disease (p = 0.09), but there was a tendency for horses with bilateral disease to have clinical signs for longer. Age (p = 0.19) and hospitalization duration (p = 0.53) did not differ between horses undergoing unilateral versus bilateral procedures. Recurrence or failure to resolve signs was reported in 11/32 (34%) of unilateral and 0/5 bilateral cases (p = 0.07). The bilateral single, caudally based sinusotomy approach may be considered to effectively treat bilateral paranasal sinus disease without concern for increased risk of life-threatening complications or longer hospitalization duration than would be typical for unilateral sinusotomy procedures.
© 2021 The Authors. Veterinary Medicine and Science published by John Wiley & Sons Ltd.
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Publication Date: 2021-08-17 PubMed ID: 34405566PubMed Central: PMC8604118DOI: 10.1002/vms3.607Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research examines the outcomes of two types of surgical treatments for equine paranasal sinus disease, unilateral and bilateral sinusotomy. It concludes that bilateral sinusotomy may be a more effective treatment for bilateral paranasal sinus disease, without leading to increased risks or extended hospital stays.

Clinical Features and Outcomes

  • The researchers describe the clinical features and outcomes of horses who underwent a standing single, caudally based bilateral frontonasal sinusotomy as compared to those who had a unilateral frontonasal surgery.
  • The surgical treatments were administered to a total of 37 horses suffering from sinus disease. Out of these, five underwent bilateral sinusotomy, while 32 had a unilateral procedure.
  • The study retrospectively reviews the records of these horses from 2010 to 2017, including their symptoms, duration of signs preoperatively, diagnostic imaging, treatments received, duration of hospitalization, complications, and owner satisfaction.

Comparative Analysis

  • The researchers used Mann-Whitney testing to compare age, duration of hospital stay, and follow-up time in horses undergoing either unilateral or bilateral procedures.
  • Fisher’s exact test was used to find out if a sex predilection existed for unilateral or bilateral disease.
  • Survival time and time to recurrence were compared using Kaplan-Meier survival curves and log-rank curve comparison testing.

Results

  • The study found no significant difference in the length of signs prior to admission between horses with unilateral and bilateral disease. However, there was a tendency for horses with bilateral disease to show clinical signs for a longer period.
  • There was no significant difference in terms of age and hospitalization duration between horses undergoing unilateral versus bilateral procedures.
  • Recurrence or failure to resolve signs was reported in 34% of unilateral cases and none of the bilateral cases, although the difference was marginally non-significant (p=0.07).
  • Overall, the study suggests that, for treating bilateral paranasal sinus disease, the bilateral single, caudally based sinusotomy method may be a preferred choice, as it didn’t show an increased risk of life-threatening complications or longer hospitalization duration compared to unilateral sinusotomy procedures.

Cite This Article

APA
Pezzanite LM, Hackett ES, McCready E, Easley JT. (2021). Outcomes following single, caudally based bilateral versus unilateral frontonasal sinusotomy for treatment of equine paranasal sinus disease. Vet Med Sci, 7(6), 2209-2218. https://doi.org/10.1002/vms3.607

Publication

Veterinary medicine and science
ISSN: 2053-1095
NlmUniqueID: 101678837
Country: England
Language: English
Volume: 7
Issue: 6
Pages: 2209-2218

Researcher Affiliations

Pezzanite, Lynn M
  • Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Hackett, Eileen S
  • Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
McCready, Erin
  • Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Easley, Jeremiah T
  • Preclinical Surgical Research Laboratory, Department of Clinical Sciences, Veterinary Teaching Hospital, Translational Medicine Institute, Colorado State University, Fort Collins, Colorado, USA.

MeSH Terms

  • Animals
  • Horse Diseases / diagnosis
  • Horse Diseases / surgery
  • Horses
  • Paranasal Sinus Diseases / surgery
  • Paranasal Sinus Diseases / veterinary
  • Retrospective Studies

Grant Funding

  • TL1 TR002533 / NCATS NIH HHS
  • T32 OD010437 / NIH HHS

Conflict of Interest Statement

The authors declare no conflict of interest.

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Citations

This article has been cited 1 times.
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