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The Veterinary record1993; 132(8); 179-182; doi: 10.1136/vr.132.8.179

Pathological lesions associated with Anoplocephala perfoliata at the ileo-caecal junction of horses.

Abstract: The intestinal tracts of 20 horses, killed at a local abattoir and of unknown age, sex and previous clinical history were examined for the presence of Anoplocephala perfoliata attached to the ileo-caecal junction. Four horses had no tape-worms, nine had one to 20 tapeworms attached to the mucosa and seven had more than 100 attached to the mucosa. The histological changes of thickening, ulceration and eosinophil infiltration of the mucosa at the ileo-caecal junction were more severe when more than 100 parasites were present.
Publication Date: 1993-02-20 PubMed ID: 8451801DOI: 10.1136/vr.132.8.179Google Scholar: Lookup
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  • Journal Article

Summary

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The study examined intestines from 20 horses to determine the damage caused by Anoplocephala perfoliata, a type of tapeworm, particularly at the ileo-caecal junction. It was found that the presence of more than 100 of these parasites resulted in severe intestinal damage.

Research Objective and Methodology

  • The primary aim of this study was to investigate the pathological damage caused by the tapeworm Anoplocephala perfoliata at the ileo-caecal junction of horses.
  • To achieve this, the researchers examined the intestinal tracts of 20 horses that were killed at a local abattoir. The horses’ age, sex, and previous clinical history were unknown.
  • The scientists specifically searched for the presence of Anoplocephala perfoliata tapeworms attached to the ileo-caecal junction, a critical region where the small intestine meets the large intestine.

Findings and Conclusions

  • Out of the 20 horses studied, four had no tapeworms, nine had between one to 20 tapeworms attached to the intestinal mucosa, and seven had more than 100 tapeworms attached to the mucosa.
  • It was observed that the pathological changes in the ileo-caecal junction’s mucosal lining, such as thickening, ulceration, and an influx of eosinophils (white blood cells that fight infections), were more severe in horses with more than 100 parasites.
  • Based on these findings, the study implies that a higher infestation of Anoplocephala perfoliata tapeworms in the ileo-caecal junction can lead to significant pathological damage, negatively affecting the health condition of the horse.
  • Although the sample size was small, this study provides essential insights into horse veterinary medicine, demystifying the impact of Anoplocephala perfoliata parasite burden on the ileo-caecal junction.

Cite This Article

APA
Pearson GR, Davies LW, White AL, O'Brien JK. (1993). Pathological lesions associated with Anoplocephala perfoliata at the ileo-caecal junction of horses. Vet Rec, 132(8), 179-182. https://doi.org/10.1136/vr.132.8.179

Publication

ISSN: 0042-4900
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 132
Issue: 8
Pages: 179-182

Researcher Affiliations

Pearson, G R
  • Department of Pathology and Microbiology, University of Bristol, School of Veterinary Science, Langford.
Davies, L W
    White, A L
      O'Brien, J K

        MeSH Terms

        • Abattoirs
        • Animals
        • Cestoda / isolation & purification
        • Cestode Infections / parasitology
        • Cestode Infections / pathology
        • Cestode Infections / veterinary
        • England
        • Eosinophils
        • Horse Diseases / parasitology
        • Horse Diseases / pathology
        • Horses
        • Ileal Diseases / parasitology
        • Ileal Diseases / pathology
        • Ileal Diseases / veterinary
        • Ileocecal Valve / parasitology
        • Ileocecal Valve / pathology
        • Intestinal Diseases, Parasitic / parasitology
        • Intestinal Diseases, Parasitic / pathology
        • Intestinal Diseases, Parasitic / veterinary
        • Intestinal Mucosa / parasitology
        • Intestinal Mucosa / pathology
        • Leukocyte Count / veterinary

        Citations

        This article has been cited 8 times.
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        2. Wititkornkul B, Hulme BJ, Tomes JJ, Allen NR, Davis CN, Davey SD, Cookson AR, Phillips HC, Hegarty MJ, Swain MT, Brophy PM, Wonfor RE, Morphew RM. Evidence of Immune Modulators in the Secretome of the Equine Tapeworm Anoplocephala perfoliata. Pathogens 2021 Jul 20;10(7).
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        3. Slater R, Frau A, Hodgkinson J, Archer D, Probert C. A Comparison of the Colonic Microbiome and Volatile Organic Compound Metabolome of Anoplocephala perfoliata Infected and Non-Infected Horses: A Pilot Study. Animals (Basel) 2021 Mar 9;11(3).
          doi: 10.3390/ani11030755pubmed: 33803473google scholar: lookup
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          doi: 10.1007/s00436-012-3117-1pubmed: 23001508google scholar: lookup
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          doi: 10.1007/s11259-012-9516-zpubmed: 22294318google scholar: lookup
        6. Slocombe JO. A modified critical test for the efficacy of pyrantel pamoate for Anoplocephala perfoliata in equids. Can J Vet Res 2004 Apr;68(2):112-7.
          pubmed: 15188955
        7. Ihler CF, Rootwelt V, Heyeraas A, Dolvik NJ. The prevalence and epidemiology of Anoplocephala perfoliata infection in Norway. Vet Res Commun 1995;19(6):487-94.
          doi: 10.1007/BF01839337pubmed: 8619287google scholar: lookup
        8. Nilsson O, Ljungström BL, Höglund J, Lundquist H, Uggla A. Anoplocephala perfoliata in horses in Sweden: prevalence, infection levels and intestinal lesions. Acta Vet Scand 1995;36(3):319-28.
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