Peripheral blood leukocytes.
Abstract: Assessment of peripheral blood leukocytes is the most common clinical pathology test in equine practice. It is always a part of complete body function assessment and frequently is used alone, or in conjunction with, fibrinogen to monitor response to treatment.
Publication Date: 2008-07-26 PubMed ID: 18652954DOI: 10.1016/j.cveq.2008.05.003Google Scholar: Lookup
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Summary
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The body of research focuses on the importance of analyzing peripheral blood leukocytes, a type of white blood cell, in equine veterinary care, and how it aids in a comprehensive assessment of an animal’s body function and evaluation of treatment response often alongside fibrinogen.
Importance of Peripheral Blood Leukocytes
- Peripheral blood leukocytes, more commonly known as white blood cells, are a crucial part of the immune system. They help fight off infections and diseases in the body. Assessing these cells gives insight into an animal’s health and immune function.
- In equine practice, assessment of these white blood cells is a standard procedure. It forms the most common clinical pathology test, practically always forming part of a complete body function assessment.
- The assessment of leukocytes is of quintessence in diagnosing, monitoring, and managing various infectious and non-infectious diseases in horses. Changes in leukocyte count can indicate several conditions such as inflammation, infection, or immune disorders. Thus it is critical for maintaining equine health.
Role in Treatment Response Monitoring
- Leukocytes concentration is not only used for diagnosing health conditions but also used in conjunction, frequently with fibrinogen, to monitor treatment response.
- Fibrinogen is a protein involved in blood clotting. Elevated levels could indicate inflammation or tissue damage. Hence, tracking both leukocytes and fibrinogen can offer comprehensive insights into a horse’s health status and response to treatment, hemostasis, and inflammation.
- Monitoring the levels during treatment allows veterinarians to understand whether the treatment being administered is effective, needs adjustments, or should be replaced with a different approach. Therefore, providing a more personalized treatment plan, thus improving the outcomes for the patient.
Cite This Article
APA
Carrick JB, Begg AP.
(2008).
Peripheral blood leukocytes.
Vet Clin North Am Equine Pract, 24(2), 239-v.
https://doi.org/10.1016/j.cveq.2008.05.003 Publication
Researcher Affiliations
- Scone Veterinary Laboratory, Scone Veterinary Hospital, 106 Liverpool Street, Scone, NSW, Australia. joan.carrick@sconevet.com.au
MeSH Terms
- Animals
- Hematology / methods
- Horse Diseases / immunology
- Horses
- Leukocyte Count / veterinary
- Leukocytes / immunology
- Leukocytes / physiology
Citations
This article has been cited 15 times.- Colleselli K, Ebeyer-Masotta M, Neuditschko B, Stierschneider A, Pollhammer C, Potocnjak M, Hundsberger H, Herzog F, Wiesner C. Beyond Pattern Recognition: TLR2 Promotes Chemotaxis, Cell Adhesion, and Migration in THP-1 Cells. Cells 2023 May 19;12(10).
- Li R, Li L, Liu B, Luo D, Xiao S. Associations of levels of peripheral blood leukocyte and subtypes with type 2 diabetes: A longitudinal study of Chinese government employees. Front Endocrinol (Lausanne) 2023;14:1094022.
- Zhu Y, Chen J, Li J, Zhou C, Huang X, Chen B. Ginsenoside Rg1 as a promising adjuvant agent for enhancing the anti-cancer functions of granulocytes inhibited by noradrenaline. Front Immunol 2023;14:1070679.
- Schoenberg MB, Han Y, Li X, Li X, Bucher JN, Börner N, Koch D, Guba MO, Werner J, Bazhin AV. Dynamics of Peripheral Blood Immune Cells during the Perioperative Period after Digestive System Resections: A Systematic Analysis of the Literature. J Clin Med 2023 Jan 16;12(2).
- Rusconi G, Cusumano G, Mariotta L, Canevascini R, Gola M, Gornati R, Soldati G. Upgrading Monocytes Therapy for Critical Limb Ischemia Patient Treatment: Pre-Clinical and GMP-Validation Aspects. Int J Mol Sci 2022 Oct 21;23(20).
- Liu D, Dong S, Liu C, Du J, Wang S, Yu H, Li W, Chen Z, Peng R, Jiang Q, Zou M, Li F, Zhang R. CRX-527 induced differentiation of HSCs protecting the intestinal epithelium from radiation damage. Front Immunol 2022;13:927213.
- Li P, Liu Y, Gao M, Fu J, Guo Y. Dietary Soy Saponin Improves Antioxidant and Immune Function of Layer Hens. J Poult Sci 2022 Jul 25;59(3):197-205.
- Pu L, Sun P. The Systematic Analysis of Exercise Mechanism in Human Diseases. Genet Res (Camb) 2022;2022:8555020.
- Celliers A, Rautenbach Y, Hooijberg E, Christopher M, Goddard A. Neutrophil Myeloperoxidase Index in Dogs With Babesiosis Caused by Babesia rossi. Front Vet Sci 2020;7:72.
- Okafor M, Faller P, Vitale N. Cell-specific copper dyshomeostasis mechanism in Alzheimer's disease. Transl Neurodegener 2025 Aug 22;14(1):42.
- de Oliveira DA, Oliveira R, Braga BV, Straker LC, Rodrigues LS, Bueno LL, Fujiwara RT, Lopes-Torres EJ. Experimental trichuriasis: Changes in the immune response and bacterial translocation during acute phase development illustrated with 3D model animation. PLoS Negl Trop Dis 2025 Feb;19(2):e0012841.
- Ochoa-Amaya JE, Paula LOA, Luciano FF, Bernardi MM. Repeated saline injections reduce the pulmonary allergic inflammatory response in rats by inducing short-term stress. Brain Behav Immun Health 2024 Oct;40:100822.
- Orzołek A, Rafalska KT, Domosławska-Wyderska A, Rafalska AM, Dziekońska A, Jastrzębska E, Dobbek D. The effect of solarium light therapy on selected biological and biochemical parameters of peripheral blood in young and old horses. PLoS One 2024;19(5):e0304290.
- Visser M, Hof WFJ, Broek AM, van Hoek A, de Jong JJ, Touw DJ, Dekkers BGJ. Unexpected Amanita phalloides-Induced Hematotoxicity-Results from a Retrospective Study. Toxins (Basel) 2024 Jan 29;16(2).
- Huang X, Ouyang Q, Ran M, Zeng B, Deng L, Hu S, Yang M, Li G, Deng T, He M, Li T, Yang H, Zhang G, Zhang H, Zeng C, Wang J. The immune and metabolic changes with age in giant panda blood by combined transcriptome and DNA methylation analysis. Aging (Albany NY) 2020 Nov 7;12(21):21777-21797.
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