Potential differences between Leptospira serovars, host-adapted (Bratislava) and incidental (Copenhageni), in determining reproductive disorders in embryo transfer recipient mares in Brazil.
Abstract: The objective was to investigate potential differences between two Leptospira serovars, host-adapted (Bratislava) and incidental (Copenhageni), in causing reproductive disorders in mares. From August 2009 to March 2011, 608 adult recipient mares from eight studs located in the state of Rio de Janeiro, Brazil, were screened for leptospirosis. These mares were 3-8 years of age, of various breeds, and were managed in a semiextensive system (embryo transfer centres). According to the reproductive history of these mares, the studs were categorised as Group A (357 mares: high prevalence of reproductive problems), and Group B (251 mares: all pregnant). Of the 608 samples tested serologically, 273 (44.9 per cent) were reactive (titres ≥200), predominantly against Bratislava (62.3 per cent of reactive mares). In Group A, 247/357 sera (69.2 per cent) were reactive, with reactivity against Bratislava (64.8 per cent of reactive). By contrast, in Group B, only 26/251 sera (10.4 per cent) were reactive, the majority against Copenhageni (61.5 per cent of reactive). Seroreactivity against Bratislava was more likely to be associated (P<0.001) with reproductive problems than seroreactivity against Copenhageni; this association was true for early embryonic death (P<0.001), perinatal death (P<0.01), and abortion (P<0.001). Additionally, 29 urine samples were collected (from Group A mares) for Leptospira species PCR, of which 16 were positive (55.2 per cent). We concluded that leptospirosis was associated with poor reproductive performance in embryo recipients, with the majority due to host-adapted Bratislava.
British Veterinary Association.
Publication Date: 2014-04-02 PubMed ID: 24696445DOI: 10.1136/vr.101444Google Scholar: Lookup
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- Journal Article
Summary
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This research aims to study the impact of two different Leptospira strains on reproductive disorders in Brazilian mares. Specifically, the study found that host-adapted Bratislava was more likely associated with reproductive issues in mares than incidental Copenhageni.
Introduction and Study Design
- The objective of the study was to examine possible distinctions between two kinds of Leptospira serovars (strains), which are host-adapted (Bratislava) and incidental (Copenhageni).
- The researchers used a sample of 608 adult mares from eight studs in Rio de Janeiro, Brazil, for their investigation. These mares were between 3-8 years of age and belonged to various breeds.
- They were managed in a semiextensive system specifically at embryo transfer centres.
- Based on the reproductive history, the mares were divided into two groups: Group A, which contained mares with a high prevalence of reproductive issues and Group B, comprising only pregnant mares.
Results and Findings
- Out of the 608 samples tested serologically, 44.9 per cent (273 mares) were reactive with titres greater than or equal to 200. The majority (62.3 per cent) were reactivate against Bratislava.
- In Group A, 69.2 per cent (247 mares) were reactive, with most (64.8 per cent) being reactive against Bratislava.
- Contrastingly, in Group B, only 10.4 per cent (26 mares) were reactive, with the majority testing positive for the Copenhageni strain.
- The researchers found that mares who were seroreactive to Bratislava were more likely (P<0.001) to encounter reproductive issues than those reactive to Copenhageni. These issues included early embryonic death, perinatal death, and abortion.
Conclusions
- A total of 29 urine samples were collected from Group A mares for Leptospira species Polymerase Chain Reaction (PCR) testing. 55.2 per cent of these samples came out positive.
- The research concluded that Leptospira, notably the host-adapted Bratislava strain, was linked with poor reproductive performance in embryo recipients.
Cite This Article
APA
Pinna A, Martins G, Hamond C, Medeiros MA, de Souza GN, Lilenbaum W.
(2014).
Potential differences between Leptospira serovars, host-adapted (Bratislava) and incidental (Copenhageni), in determining reproductive disorders in embryo transfer recipient mares in Brazil.
Vet Rec, 174(21), 531.
https://doi.org/10.1136/vr.101444 Publication
Researcher Affiliations
- Laboratory of Veterinary Bacteriology, Universidade Federal Fluminense, Niterói, RJ 24210-130, Brazil.
- Laboratory of Veterinary Bacteriology, Universidade Federal Fluminense, Niterói, RJ 24210-130, Brazil.
- Laboratory of Veterinary Bacteriology, Universidade Federal Fluminense, Niterói, RJ 24210-130, Brazil.
- Bio-Manguinhos, Oswaldo Cruz Foundation, Brazilian Ministry of Health, Rio de Janeiro, RJ 21040-360, Brazil.
- Embrapa Dairy Cattle, Juiz de Fora, MG 36038-330, Brazil.
- Laboratory of Veterinary Bacteriology, Universidade Federal Fluminense, Niterói, RJ 24210-130, Brazil.
MeSH Terms
- Animals
- Brazil
- Embryo Transfer / veterinary
- Female
- Horse Diseases / microbiology
- Horses
- Leptospira / classification
- Leptospirosis / microbiology
- Leptospirosis / veterinary
- Pregnancy
- Reproduction / physiology
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