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Veterinary surgery : VS2009; 38(3); 368-372; doi: 10.1111/j.1532-950X.2008.00479.x

Prevalence of and risk factors for postoperative ileus after small intestinal surgery in two hundred and thirty-three horses.

Abstract: To determine the incidence of postoperative ileus (POI) in a population of horses after small intestinal surgery and the effect of multiple variables on development of POI. Methods: Case series. Methods: Horses (n=233) aged > or =1 year that had exploratory celiotomy for small intestinal disease that recovered from surgery from 1995 to 2005. Methods: Sixty-eight variables were collected from medical records (1995-2005) for each horse. POI was defined as nasogastric reflux volume >20 L over 24 hours or >8 L at any single time after surgery. Results: Twenty-seven percent (64/233) of horses developed POI; 29 of 64 (46%) horses with POI had duodenitis proximal jejunitis (DPJ). When no intestinal resection was required at surgery, excluding horses with DPJ, 15% of horses had POI; 30% horses had POI after intestinal resection. Ten percent of horses had POI for >24 hours. When horses with DPJ were excluded, factors associated with increased risk of POI included high packed cell volume at hospital admission (P=.024), increasing age (P=.0004), and length of intestinal resection (P=.05). Conclusions: Risk factors for POI in this study were nonspecific although horses with intestinal resection are at higher risk compared with horses without intestinal resection. Conclusions: Predicting with certainty which cases will develop POI remains elusive.
Publication Date: 2009-07-04 PubMed ID: 19573101DOI: 10.1111/j.1532-950X.2008.00479.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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The research investigates the frequency of postoperative ileus, a type of paralysis, in horses after small intestinal surgery, as well as factors that may influence its occurrence. It found that horses with certain characteristics such as older age, high cellular volume at admission, and length of intestinal resection are at a higher risk of developing the condition.

Introduction and Methodology

  • The study is a case series that encompassed over a decade of medical records, stretching from 1995 to 2005, for horses that had undergone small intestinal surgery. The surgery was specifically ‘exploratory celiotomy’, a common type of abdominal surgery in horses. The study involved a sizable number of horses aged one year or older, with a total of 233 subjects.
  • The researchers collected data on 68 variables from the medical records for each horse. These variables were presumably related to the horses’ physical condition, medical history, and details of the surgery performed. Postoperative ileus (POI), a condition where the intestines cease to function normally following surgery, was defined based on the volume of reflux (the backward flow of digested food) observed over a specific timeframe.

Results

  • The study found that roughly 27 percent of the examined horses developed POI after surgery.
  • Of the horses that developed POI, a notable 46 percent had a condition called duodenitis proximal jejunitis (DPJ). This suggests a possible association between DPJ and the development of POI, although the article does not draw a direct link.
  • The figures differ when considering the type of treatment received in surgery. The study found that 15 percent of horses that required no intestinal resection during the operation developed POI, while 30 percent did so after intestinal resection. This indicates that the removal of a part of the intestine may increase the risk of developing POI.
  • Some of the horses suffered from the condition for over 24 hours, becoming a longer-term issue. Notably, however, this was only the case for 10 percent of the horses.

Conclusions

  • The study identified some risk factors for the development of POI in horses following small intestinal surgery, including high packed cell volume at hospital admission and increasing age. They found these factors to be associated with an increased risk of developing POI, particularly for those not suffering from DPJ.
  • One other significant factor identified was the length of intestinal resection. The longer this was, the higher the risk of POI development.
  • While the study identified some patterns and potential risk factors, it concluded that predicting with certainty which horses will develop POI remains a challenge. This implies that further research is needed in this area and other factors not covered in this study may also play a role.

Cite This Article

APA
Holcombe SJ, Rodriguez KM, Haupt JL, Campbell JO, Chaney KP, Sparks HD, Hauptman JG. (2009). Prevalence of and risk factors for postoperative ileus after small intestinal surgery in two hundred and thirty-three horses. Vet Surg, 38(3), 368-372. https://doi.org/10.1111/j.1532-950X.2008.00479.x

Publication

ISSN: 1532-950X
NlmUniqueID: 8113214
Country: United States
Language: English
Volume: 38
Issue: 3
Pages: 368-372

Researcher Affiliations

Holcombe, Susan J
  • Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI48824, USA. Holcombe@cvm.msu.edu
Rodriguez, Katie M
    Haupt, Jennifer L
      Campbell, James O
        Chaney, Kristin P
          Sparks, Holly D
            Hauptman, Joe G

              MeSH Terms

              • Animals
              • Female
              • Horse Diseases / epidemiology
              • Horse Diseases / surgery
              • Horses
              • Ileus / epidemiology
              • Ileus / veterinary
              • Intestinal Diseases / surgery
              • Intestinal Diseases / veterinary
              • Intestine, Small / surgery
              • Male
              • Multivariate Analysis
              • Postoperative Complications / epidemiology
              • Postoperative Complications / veterinary
              • Prevalence
              • Retrospective Studies
              • Risk Factors

              Citations

              This article has been cited 4 times.
              1. Patton ME, Andrews FM, Bogers SH, Wong D, McKenzie HC 3rd, Werre SR, Byron CR. Effects of Bit Chewing on Gastric Emptying, Small Intestinal Transit, and Orocecal Transit Times in Clinically Normal Horses.. Animals (Basel) 2023 Aug 4;13(15).
                doi: 10.3390/ani13152518pubmed: 37570326google scholar: lookup
              2. Verhaar N, Hoppe S, Grages AM, Hansen K, Neudeck S, Kästner S, Mazzuoli-Weber G. Dexmedetomidine Has Differential Effects on the Contractility of Equine Jejunal Smooth Muscle Layers In Vitro.. Animals (Basel) 2023 Mar 10;13(6).
                doi: 10.3390/ani13061021pubmed: 36978562google scholar: lookup
              3. Cuevas-Ramos G, Domenech L, Prades M. Small Intestine Ultrasound Findings on Horses Following Exploratory Laparotomy, Can We Predict Postoperative Reflux?. Animals (Basel) 2019 Dec 9;9(12).
                doi: 10.3390/ani9121106pubmed: 31835406google scholar: lookup
              4. Torfs SC, Maes AA, Delesalle CJ, Pardon B, Croubels SM, Deprez P. Plasma serotonin in horses undergoing surgery for small intestinal colic.. Can Vet J 2015 Feb;56(2):178-84.
                pubmed: 25694668