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Frontiers in veterinary science2022; 9; 923657; doi: 10.3389/fvets.2022.923657

Prevalence of brucellosis in livestock of African and Asian continents: A systematic review and meta-analysis.

Abstract: Brucellosis is a highly contagious bacterial disease that mainly affects ruminants, but it may affect equines, canines, and felines. The disease is of utmost significance from an economic standpoint in countries where there is no national brucellosis prevention and eradication policy in operation. A systematic review was done to estimate disease burden, incidences, prevalence, and geographical distribution critical in planning appropriate intervention strategies for the control and prevention of Brucellosis. Research articles that were published during the period 2000-2020 were considered for this study after reinforced scrutiny by two independent authors. Meta-regression was used to examine heterogeneity, and subgroup and sensitivity analyses were used to calculate residual heterogeneity and the pooled prevalence of Brucellosis in livestock. Confounders such as geography, a diagnostic test, and species had the greatest values of 17.8, 8.8, and 2.3%, respectively, indicating the presence of heterogeneity and necessitating more research into sensitivity and subgroup analysis. The combined pooled prevalence of brucellosis in both Asia and African countries was 8% when compared to 12% in the Indian livestock population. The findings of our systematic review and meta-analysis indicate that brucellosis continues to be an important animal and public health concern in developing countries of Asia and Africa, as evidenced by the prevalence rate of brucellosis in these regions. Our findings suggested that well-planned epidemiological surveillance studies in different geographic settings are needed to generate reliable data on disease burden including the economic loss in Asian and African countries.
Copyright © 2022 Suresh, Patil, Nayak, Dhanze, Rajamani, Shivamallu, Cull and Amachawadi.
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Publication Date: 2022-09-09 PubMed ID: 36157176PubMed Central: PMC9500530DOI: 10.3389/fvets.2022.923657Google Scholar: Lookup
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  • Systematic Review

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article deals with the comprehensive scrutiny of the presence and prevalence of the bacterial disease, brucellosis, in livestock populations across Africa and Asia, using data sourced from related research articles between 2000 and 2020.

Article Methodology and Approach

  • The research conducted a systematic review in order to anticipate the burden, incidences, frequency, and geographic spread of brucellosis, which is valuable in establishing an effective strategy for its control and prevention.
  • The references for this review were extracted from studies published between 2000 and 2020, and each paper underwent rigorous examination by two independent authors to ensure the relevancy and reliability of the data.
  • Meta-regression was employed to scrutinize heterogeneity, while subgroup and sensitivity analyses were used to compute residual heterogeneity and the general prevalence of brucellosis in livestock.

Key Findings

  • Geography, diagnostic tests, and species were identified as confounding factors, having the highest heterogeneity values of 17.8%, 8.8%, and 2.3%, respectively. This suggests a need for additional sensitivity and subgroup analysis research.
  • The fuzed overall prevalence of brucellosis in Africa and Asia was discovered to be 8%, lower than the 12% observed in the livestock population in India.

Conclusion and Implications

  • The study underlines that brucellosis remains a significant issue to both animal and public health in developing Asian and African countries, highlighted by the disease’s prevalence in these areas.
  • The authors suggest that meticulous epidemiological surveillance research in a variety of geographic settings is required to yield reliable data on the burden of the disease, including the economic fallout in Asian and African nations.

Cite This Article

APA
Suresh KP, Patil SS, Nayak A, Dhanze H, Rajamani S, Shivamallu C, Cull CA, Amachawadi RG. (2022). Prevalence of brucellosis in livestock of African and Asian continents: A systematic review and meta-analysis. Front Vet Sci, 9, 923657. https://doi.org/10.3389/fvets.2022.923657

Publication

Frontiers in veterinary science
ISSN: 2297-1769
NlmUniqueID: 101666658
Country: Switzerland
Language: English
Volume: 9
Pages: 923657
PII: 923657

Researcher Affiliations

Suresh, Kuralayanapalya P
  • Spatial Epidemiology Laboratory, Indian Council of Agricultural Research (ICAR) - National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Bengaluru, Karnataka, India.
Patil, Sharanagouda S
  • Virology Laboratory, Indian Council of Agricultural Research (ICAR) - National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Bengaluru, Karnataka, India.
Nayak, Akshata
  • Spatial Epidemiology Laboratory, Indian Council of Agricultural Research (ICAR) - National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Bengaluru, Karnataka, India.
Dhanze, Himani
  • ICAR-Indian Veterinary Research Institute, Bareilly, India.
Rajamani, Shinduja
  • Spatial Epidemiology Laboratory, Indian Council of Agricultural Research (ICAR) - National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Bengaluru, Karnataka, India.
Shivamallu, Chandan
  • Division of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India.
Cull, Charley A
  • Midwest Veterinary Services, Inc., Oakland, NE, United States.
Amachawadi, Raghavendra G
  • Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.

Conflict of Interest Statement

Author CC was employed by Midwest Veterinary Services, Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Citations

This article has been cited 3 times.
  1. Moriyón I, Blasco JM, Letesson JJ, De Massis F, Moreno E. Brucellosis and One Health: Inherited and Future Challenges.. Microorganisms 2023 Aug 11;11(8).
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