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Scientific reports2020; 10(1); 8311; doi: 10.1038/s41598-020-65444-9

Priming for welfare: gut microbiota is associated with equitation conditions and behavior in horse athletes.

Abstract: We simultaneously measured the fecal microbiota and multiple environmental and host-related variables in a cohort of 185 healthy horses reared in similar conditions during a period of eight months. The pattern of rare bacteria varied from host to host and was largely different between two time points. Among a suite of variables examined, equitation factors were highly associated with the gut microbiota variability, evoking a relationship between gut microbiota and high levels of physical and mental stressors. Behavioral indicators that pointed toward a compromised welfare state (e.g. stereotypies, hypervigilance and aggressiveness) were also associated with the gut microbiota, reinforcing the notion for the existence of the microbiota-gut-brain axis. These observations were consistent with the microbiability of behaviour traits (> 15%), illustrating the importance of gut microbial composition to animal behaviour. As more elite athletes suffer from stress, targeting the microbiota offers a new opportunity to investigate the bidirectional interactions within the brain gut microbiota axis.
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Publication Date: 2020-05-20 PubMed ID: 32433513PubMed Central: PMC7239938DOI: 10.1038/s41598-020-65444-9Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research investigates the relationship between the gut microbiota (microorganisms living in intestines) and the physical and mental stress levels in 185 healthy horses over an eight months period. The study suggests that changes in gut microbiota may be associated with equitation factors and certain behavioural indicators, implying a possible connection between the gut and animal behavior, and providing new opportunities to explore the interactions within the brain-gut-microbiota axis.

Research Methodology

  • The research was conducted on a cohort of 185 healthy horses, reared in similar conditions over a span of eight months.
  • Simultaneous measurements were made of the fecal microbiota and multiple environmental and host-related variables.
  • The variability pattern of rare bacteria was examined across host to host and between two time points.

Research Findings

  • Among many variables examined, equitation factors (training methods, workload, rider’s skill level, and saddle fit) were strongly associated with gut microbiota variability. This reflects a relationship between gut microbiota and high physical and mental stress in horse athletes.
  • Behavioural indicators such as hypervigilance, stereotypies, and aggressiveness that suggest a compromised welfare state were prominently linked with gut microbiota. This goes to strengthen the idea of a microbiota-gut-brain axis, where changes in microbiota could impact behaviour.
  • Common behavioural traits were found to be dependent on the microbiotal makeup by over 15%, highlighting the substantial role of gut microbial composition in determining animal behaviour.

Research Implications and Future Directions

  • The study provides valuable insights for athletes, especially elite ones, as they often suffer from high stress levels. Understanding the interaction between gut microbiota and stress can offer new avenues for stress management practices.
  • The research illuminates the bi-directional interactions within the brain-gut-microbiota axis and its effect on animal behavior, which could pave the way for future research in manipulating microbiota to influence behavior and manage stress.

Cite This Article

APA
Mach N, Ruet A, Clark A, Bars-Cortina D, Ramayo-Caldas Y, Crisci E, Pennarun S, Dhorne-Pollet S, Foury A, Moisan MP, Lansade L. (2020). Priming for welfare: gut microbiota is associated with equitation conditions and behavior in horse athletes. Sci Rep, 10(1), 8311. https://doi.org/10.1038/s41598-020-65444-9

Publication

Scientific reports
ISSN: 2045-2322
NlmUniqueID: 101563288
Country: England
Language: English
Volume: 10
Issue: 1
Pages: 8311
PII: 8311

Researcher Affiliations

Mach, Núria
  • Animal Genetic and Integrative Biology, INRAE, University of Paris-Saclay, AgroParisTech, 78350, Jouy-en-Josas, France. nuria.mach@inrae.fr.
Ruet, Alice
  • PRC, INRAE, CNRS, IFCE, University of Tours, 37380, Nouzilly, France.
Clark, Allison
  • Health Science Department, Open University of Catalonia, 08018, Barcelona, Spain.
Bars-Cortina, David
  • Medicine Department, University of Lleida, 25001, Lleida, Spain.
Ramayo-Caldas, Yuliaxis
  • Animal Genetic and Integrative Biology, INRAE, University of Paris-Saclay, AgroParisTech, 78350, Jouy-en-Josas, France.
  • Animal Breeding and Genetics Program, Institute for Research and Technology in Food and Agriculture (IRTA), Torre Marimon, 08140, Caldes de Montbui, Spain.
Crisci, Elisa
  • Animal Genetic and Integrative Biology, INRAE, University of Paris-Saclay, AgroParisTech, 78350, Jouy-en-Josas, France.
  • Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, 27607, USA.
Pennarun, Samuel
  • US UMR 1426, INRAE, Genomic platform, 31326, Castanet-Tolosan, France.
Dhorne-Pollet, Sophie
  • Animal Genetic and Integrative Biology, INRAE, University of Paris-Saclay, AgroParisTech, 78350, Jouy-en-Josas, France.
Foury, Aline
  • University of Bordeaux, INRAE, NutriNeuro UMR 1286, 33076, Bordeaux, France.
Moisan, Marie-Pierre
  • University of Bordeaux, INRAE, NutriNeuro UMR 1286, 33076, Bordeaux, France.
Lansade, Léa
  • PRC, INRAE, CNRS, IFCE, University of Tours, 37380, Nouzilly, France.

MeSH Terms

  • Animals
  • Behavior, Animal
  • Biodiversity
  • Cohort Studies
  • Environment
  • Feces / microbiology
  • Female
  • Gastrointestinal Microbiome / physiology
  • Health Status
  • Horses / microbiology
  • Horses / physiology
  • Male
  • Phenotype
  • Physical Conditioning, Animal
  • Sports

Conflict of Interest Statement

The authors declare no competing interests.

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