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[Re-emergence of Venezuelan equine encephalitis virus in French Guiana. Apropos of 1 confirmed case].

Abstract: Venezuelan equine encephalitis (VEE) is a mosquito-borne viral disease that occurs in equine species and in man. The strains can be grouped epidemiologically into two major categories: enzootic and epizootic. Enzootic strains cause sporadic human disease and are not associated with disease among equines. These strains are found throughout Florida. Central America, northern South America and Brazil. Epizootic strains are associated with enormous morbidity and mortality in equine species. In man, VEE virus infections are largely asymptomatic and in children and young adults there is an increased risk of encephalitis and dead. We report the first case in French Guiana of Venezuelan equine encephalitis. Clinical examination and biological studies showed encephalitis, interstitial pneumonia and acute liver failure. Despite an adequate symptomatic treatment, the young patient died five days after her admission in multiple organ dysfunction syndrome. Diagnosis is establishing by virologic test: VEE virus is isolated from the blood. These example of re-emerging infectious disease vividly illustrate that we remains vulnerable and emphasizes the need for an active surveillance system.
Publication Date: 1997-01-01 PubMed ID: 9410246
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Summary

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The research discusses the reappearance of Venezuelan equine encephalitis (VEE) virus in French Guiana, focusing on a case study of a young patient who developed severe symptoms and sadly passed away from the disease, demonstrating the need for ongoing surveillance to manage outbreaks of infectious diseases like VEE.

Overview of Venezuelan equine encephalitis (VEE)

  • VEE is a disease predominantly transmitted by mosquitoes
  • VEE primarily affects equine species (horses, donkeys, zebras, etc.) but can also infect humans
  • There are two main types of the virus – enzootic and epizootic. The former usually causes infrequent diseases in humans and is not connected with disease in equines, and the latter is associated with large-scale illness and mortality in equine species.

Introduction of VEE in French Guiana

  • The researchers present the first documented case of VEE in French Guiana.
  • The patient was a young individual who came down with encephalitis, intersitial pneumonia, and acute liver failure – all critical conditions subsumed under VEE.
  • The patient’s condition worsened rapidly, leading to their death within five days from multiple organ dysfunction syndrome, in spite of adequate symptomatic treatment.

Diagnosis and Significance of the Findings

  • The diagnosis was established through virological testing, with the VEE virus found in the patient’s blood sample.
  • This investigation provides a vivid example of how infectious diseases can re-emerge and serve as a reminder of our susceptibility to them. It stresses the importance of an active surveillance system in monitoring and managing such diseases.

Cite This Article

APA
Hommel D, Bollandard F, Hulin A. (1997). [Re-emergence of Venezuelan equine encephalitis virus in French Guiana. Apropos of 1 confirmed case]. Bull Soc Pathol Exot, 90(3), 153-155.

Publication

ISSN: 0037-9085
NlmUniqueID: 9212564
Country: France
Language: fre
Volume: 90
Issue: 3
Pages: 153-155

Researcher Affiliations

Hommel, D
  • Unité de réanimation polyvalente, Centre hospitalier de Cayenne, Guyane française.
Bollandard, F
    Hulin, A

      MeSH Terms

      • Blood / virology
      • Child, Preschool
      • Encephalitis Virus, Venezuelan Equine / isolation & purification
      • Encephalomyelitis, Venezuelan Equine / diagnosis
      • Encephalomyelitis, Venezuelan Equine / therapy
      • Encephalomyelitis, Venezuelan Equine / virology
      • Fatal Outcome
      • Female
      • French Guiana
      • Humans

      Citations

      This article has been cited 1 times.
      1. Mutricy R, Djossou F, Matheus S, Lorenzi-Martinez E, De Laval F, Demar M, Nacher M, Rousset D, Epelboin L. Discriminating Tonate Virus from Dengue Virus Infection: A Matched Case-Control Study in French Guiana, 2003-2016. Am J Trop Med Hyg 2020 Jan;102(1):195-201.
        doi: 10.4269/ajtmh.19-0156pubmed: 31769401google scholar: lookup