Regenerative Medicine Therapies for Equine Wound Management.
Abstract: Wound management in horses can strike fear in some and passion in others. Wounds are common injuries in horses of all descriptions and requires exceptional knowledge and care to achieve a successful outcome. New treatments to overcome the critical challenges with equine wounds are always desired: managing dehisced and/or nonhealing wounds, managing exuberant granulation tissue, and ultimately achieving a functional tissue coverage. Regenerative medicine represents a broad set of tools with great promise to manipulate the deficiencies recognized in equine wound healing and improve the outcome.
Copyright © 2018 Elsevier Inc. All rights reserved.
Publication Date: 2018-11-19 PubMed ID: 30447771DOI: 10.1016/j.cveq.2018.07.009Google Scholar: Lookup
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Summary
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The research article discusses the potential of regenerative medicine therapies in improving wound management for horses, addressing challenges such as nonhealing wounds, exuberant granulation tissue, and functional tissue coverage.
Overview of Equine Wound Management
- According to the article, managing wounds in horses is a common issue and requires significant knowledge and care for successful recovery. These wounds often present unique challenges, including dehisced or nonhealing wounds, where the wound edges separate before healing has completed or wounds that, for various reasons, do not heal as expected.
- Another issue discussed is the management of exuberant granulation tissue. This refers to an overgrowth of new tissue during the healing process, which can inhibit proper wound closure.
- The final challenge addressed is achieving functional tissue coverage. This means ensuring that the wound heals in such a way that the affected area regains its full function, whether that be movement, sensation, or other aspects of normal tissue function.
Regenerative Medicine Therapies for Equine Wound Management
- The research paper examines the potential of regenerative medicine as a solution to these challenges. Regenerative medicine involves using cells, biomolecules, and other medical technologies to heal or replace damaged tissues and organs. This approach aims to restore the regular structure and function of the wounded area.
- The authors suggest that regenerative medicine offers a broad toolset that could be used to address known deficiencies in equine wound healing. The idea is to harness the body’s inherent ability to heal itself, but guide and augment this process where typical healing responses are found to be lacking.
Implications and Potential benefits
- The potential benefits of successfully applying regenerative medicine to equine wound management are significant. For instance, if nonhealing wounds can be encouraged to heal correctly through these techniques, it would reduce the need for additional interventions such as surgical debridement or intensive wound care.
- Faster, more comprehensive healing could also improve the quality of life for affected horses by minimizing discomfort and long-term complications from the wound.
- In terms of industry impact, if these therapies prove to be effective, they could significantly alter the standard approach to wound management in equine care, leading to better patient outcomes and potential cost savings in the long run.
Cite This Article
APA
Dahlgren LA.
(2018).
Regenerative Medicine Therapies for Equine Wound Management.
Vet Clin North Am Equine Pract, 34(3), 605-620.
https://doi.org/10.1016/j.cveq.2018.07.009 Publication
Researcher Affiliations
- Department of Large Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, 205 Duck Pond Drive, VA 24061-0442, USA. Electronic address: lad11@vt.edu.
MeSH Terms
- Animals
- Horse Diseases / therapy
- Horses
- Regenerative Medicine
- Wound Healing
- Wounds and Injuries / therapy
- Wounds and Injuries / veterinary
Citations
This article has been cited 3 times.- Carmona JU, López C, Argüelles D. Addressing Heterogeneity in Equine PRP Therapies: A Scoping Review of Methods, Evidence, and Commercial Validation. Animals (Basel) 2025 Dec 13;15(24).
- Rosa MVD, Rosa M, Botteon PTL. Cryopreserved equine amniotic membrane and its use in cutaneous wounds of horses. Braz J Vet Med 2022;44:e003122.
- Melotti L, Carolo A, Elshazly N, Boesso F, Da Dalt L, Gabai G, Perazzi A, Iacopetti I, Patruno M. Case Report: Repeated Intralesional Injections of Autologous Mesenchymal Stem Cells Combined With Platelet-Rich Plasma for Superficial Digital Flexor Tendon Healing in a Show Jumping Horse. Front Vet Sci 2022;9:843131.
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