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Retrospective evaluation of the effect of intravenous fluid administration on development of postoperative reflux in horses with colic (2004-2012): 194 horses.

Abstract: To evaluate the role of intravenous fluid volume and electrolyte supplementation on the development of postoperative reflux (POR) in horses undergoing celiotomy for colic. Methods: Case-control study spanning 2004-2012 for horses undergoing celiotomy for colic. Methods: University teaching hospital. Methods: Sixty-seven client-owned horses >1 year of age with POR were each matched to 2 controls with similar surgical lesions that did not demonstrate POR. Results: Survival was significantly lower in cases (65.7%) than controls (96.1%). Factors found to be associated with POR included decreased net fluid volume administered on day 1 postoperatively, increased age, and performing a resection and anastomosis. Mean time until onset of POR was 20.4 hours postoperatively. PCV was significantly higher immediately following surgery and at 24 hours postoperatively in horses that developed POR compared with matched controls. There was no association between electrolyte values at presentation or administration of potassium, calcium, or magnesium in the postoperative period and the subsequent development of reflux. Conclusions: In the perioperative period, IV fluid volume overload and electrolyte abnormalities were not contributing factors in the development of POR in this population of surgical colic patients. Close postoperative monitoring with consideration and correction of pre- and postoperative fluid deficits is recommended.
Publication Date: 2018-10-09 PubMed ID: 30302921DOI: 10.1111/vec.12776Google Scholar: Lookup
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  • Clinical Trial
  • Veterinary
  • Journal Article

Summary

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This research study retrospectively evaluates the effect of intravenous (IV) fluid administration on the occurrence of postoperative reflux in horses with colic. The findings suggest that the volume and electrolyte balance of IV fluids are not contributing factors to postoperative reflux development. However, the research emphasizes the importance of closely monitoring and correcting pre- and postoperative fluid deficits.

Study Methodology

  • The research was conducted as a case-control study from 2004 to 2012 at a University teaching hospital.
  • 67 horses that had developed postoperative reflux (POR), all above one year old, were included.
  • Each of these horses were matched with two control horses that underwent similar surgical procedures but did not develop POR.

Key Findings

  • Survival rates were significantly lower in horses that developed POR (at 65.7%) compared to control horses (at 96.1%).
  • The development of POR was associated with a decrease in the net volume of fluids administered on the first day after surgery, performing a resection and anastomosis, and increased age.
  • The average time until the onset of POR was around 20.4 hours postoperatively.
  • Packed Cell Volume (PCV) was significantly higher immediately after surgery and 24 hours postoperatively in horses that developed POR compared to matched controls.
  • There was no link found between electrolyte values at admission or administration of potassium, calcium, or magnesium in the postoperative period and the subsequent development of reflux.

Conclusions

  • Contrary to what might be expected, this study concluded that neither the overload of IV fluid volume nor electrolyte abnormalities contributed to the development of POR in the observed population of surgical colic patients.
  • However, the researchers recommend vigilant postoperative monitoring to ensure that any pre- and postoperative fluid deficits are promptly identified and corrected.

Cite This Article

APA
Hoaglund EL, Hess AM, Hassel DM. (2018). Retrospective evaluation of the effect of intravenous fluid administration on development of postoperative reflux in horses with colic (2004-2012): 194 horses. J Vet Emerg Crit Care (San Antonio), 28(6), 566-572. https://doi.org/10.1111/vec.12776

Publication

ISSN: 1476-4431
NlmUniqueID: 101152804
Country: United States
Language: English
Volume: 28
Issue: 6
Pages: 566-572

Researcher Affiliations

Hoaglund, Elizabeth L
  • Departments of Clinical Sciences, Colorado State University, Fort Collins, CO, 80525.
Hess, Ann M
  • Department of Statistics, Colorado State University, Fort Collins, CO, 80525.
Hassel, Diana M
  • Departments of Clinical Sciences, Colorado State University, Fort Collins, CO, 80525.

MeSH Terms

  • Administration, Intravenous / veterinary
  • Animals
  • Case-Control Studies
  • Colic / surgery
  • Colic / veterinary
  • Digestive System Surgical Procedures / veterinary
  • Electrolytes / administration & dosage
  • Electrolytes / adverse effects
  • Female
  • Fluid Therapy / adverse effects
  • Fluid Therapy / veterinary
  • Gastroesophageal Reflux / etiology
  • Gastroesophageal Reflux / prevention & control
  • Gastroesophageal Reflux / veterinary
  • Horse Diseases / surgery
  • Horses
  • Laparotomy / veterinary
  • Male
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control
  • Postoperative Complications / veterinary
  • Retrospective Studies
  • Saline Solution / administration & dosage
  • Saline Solution / adverse effects
  • Treatment Outcome

Citations

This article has been cited 2 times.
  1. Crabtree NE, Epstein KL. Current Concepts in Fluid Therapy in Horses. Front Vet Sci 2021;8:648774.
    doi: 10.3389/fvets.2021.648774pubmed: 33855057google scholar: lookup
  2. Gomez DE, Kopper JJ, Byrne DP, Renaud DL, Schoster A, Dunkel B, Arroyo LG, Mykkanen A, Gilsenan WF, Pihl TH, Lopez-Navarro G, Tennent-Brown BS, Hostnik LD, Mora-Pereira M, Marques F, Gold JR, DeNotta SL, Desjardins I, Stewart AJ, Kuroda T, Schaefer E, Oliver-Espinosa OJ, Agne GF, Uberti B, Veiras P, Delph Miller KM, Gialleti R, John E, Toribio RE. Treatment approaches to horses with acute diarrhea admitted to referral institutions: A multicenter retrospective study. PLoS One 2024;19(11):e0313783.
    doi: 10.1371/journal.pone.0313783pubmed: 39565809google scholar: lookup