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Serologic survey for Borrelia burgdorferi antibody in horses referred to a mid-Atlantic veterinary teaching hospital.

Abstract: Blood samples obtained from 13 of 100 (13%) and 6 of 91 (7%) horses at the George D. Widener Hospital for Large Animals in the months of June and October, respectively, had antibody to Borrelia burgdorferi as determined by ELISA. Horses from the states of New York, Maryland, Delaware, New Jersey, and Pennsylvania were seropositive for B burgdorferi. The frequency of antibody response in horses from New Jersey was greater (P less than 0.05) than the frequency of antibody response in horses from Pennsylvania or that of horses from the other states combined. Statistically significant difference was not found when a comparison was made between horses with serotiter and open diagnosis of neurologic or musculoskeletal disease and horses with negative serotest results and open diagnosis of neurologic or musculoskeletal disease.
Publication Date: 1990-04-15 PubMed ID: 2332371
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  • Comparative Study
  • Journal Article

Summary

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The research article presents an investigation into the percentage of horses referred to a veterinary hospital in the mid-Atlantic region that tested positive to antibodies for Borrelia burgdorferi, the bacteria which causes Lyme disease, through blood tests.

Research Overview

  • The study took blood samples from horses referred to the George D. Widener Hospital for Large Animals in two different months, June and October.
  • The objective of this study was to determine the level of exposure to the bacteria Borrelia burgdorferi among horses in the hospital, showing how prevalent the potential for Lyme disease infection is amongst them.

Results of the Study

  • The study found that 13% and 7% of horses tested positive for the B. burgdorferi antibody in the months of June and October, respectively. This suggests a considerable number of horses have been exposed to the bacteria.
  • Horses from the states of New York, Maryland, Delaware, New Jersey, and Pennsylvania were seropositive for B. burgdorferi, meaning these horses had the B. burgdorferi antibody in their blood, a possible indicator of exposure or infection.
  • The response rate for the presence of the B. burgdorferi antibody was found to be significantly rather higher (P less than 0.05) in horses from New Jersey than those from Pennsylvania or any of the other states combined, pointing towards geographical disparities in the level of exposure to the bacteria.

Relationship between Lyme Disease and Other Conditions

  • The research investigated a possible correlation between seropositivity for B. burgdorferi and the open diagnosis of neurologic or musculoskeletal diseases in horses.
  • No statistically significant difference was established when a comparison was made between horses with serotiter and open diagnosis of these conditions and those with negative serotest results. This could indicate that the presence of Lyme disease does not significantly impact the occurrence of these conditions, or the other way round, but there’s a need for further research to determine this with certainty.

Cite This Article

APA
Bernard WV, Cohen D, Bosler E, Zamos D. (1990). Serologic survey for Borrelia burgdorferi antibody in horses referred to a mid-Atlantic veterinary teaching hospital. J Am Vet Med Assoc, 196(8), 1255-1258.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 196
Issue: 8
Pages: 1255-1258

Researcher Affiliations

Bernard, W V
  • Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.
Cohen, D
    Bosler, E
      Zamos, D

        MeSH Terms

        • Animals
        • Antibodies, Bacterial / analysis
        • Borrelia burgdorferi Group / immunology
        • Horse Diseases / epidemiology
        • Horses
        • Lyme Disease / epidemiology
        • Lyme Disease / veterinary
        • Mid-Atlantic Region / epidemiology
        • New Jersey / epidemiology
        • Pennsylvania / epidemiology
        • Prevalence

        Citations

        This article has been cited 1 times.
        1. Gehlen H, Inerle K, Bartel A, Stöckle SD, Ulrich S, Briese B, Straubinger RK. Seroprevalence of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum Infections in German Horses. Animals (Basel) 2023 Jun 14;13(12).
          doi: 10.3390/ani13121984pubmed: 37370494google scholar: lookup