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Home / Equine Research Bank / J Equine Sci / Serological evidence of equine influenza virus in horse stab...
Journal of equine science2016; 27(3); 99-105; doi: 10.1294/jes.27.99

Serological evidence of equine influenza virus in horse stables in Kaduna, Nigeria.

Abstract: Equine influenza virus (EIV) is a major cause of acute respiratory diseases in horses in most parts of the world that results in severe economic losses. Information on the epidemiology of EIV in tropical Africa is scanty. An enzyme-linked immunosorbent assay (ELISA) was used to detect the presence of influenza A virus nucleoprotein (NP) in 284 horse sera in Kaduna State, Northern Nigeria. The ELISA-positive sera were further examined for hemagglutination inhibition (HI) antibodies to two strains each of H3N8 and H7N3 subtypes of influenza A virus. The results showed that antibodies against influenza A virus nucleoprotein were detected in 60.9% (173 of 284) of horses examined by NP-ELISA. Equine H3 and H7 subtypes were detected in 60% (21 of 35) and 20% (7 of 35) of horse sera respectively across the stables. Adequate quarantine of all imported horses, a national equine influenza surveillance plan and an appropriate EIV control program in Nigeria are recommended to safeguard the large horse population.
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Publication Date: 2016-09-30 PubMed ID: 27703404PubMed Central: PMC5048356DOI: 10.1294/jes.27.99Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article reports on the prevalence of Equine Influenza Virus (EIV), a common cause of respiratory disease in horses, in horse stables in Kaduna, Nigeria. Using enzyme-linked immunosorbent assay (ELISA), the researchers found antibodies that fight against EIV in 60.9% of the tested horses.

Methodology

  • The researchers used an enzyme-linked immunosorbent assay (ELISA), a test that measures immune response in the body, to detect the presence of influenza A virus nucleoprotein (NP) in horse sera.
  • The horse sera came from 284 horses located in Kaduna State in Northern Nigeria.
  • The ELISA-positive sera were subsequently tested for hemagglutination inhibition (HI) antibodies. These antibodies fight against two strains of influenza A virus, H3N8 and H7N3.

Results and Findings

  • The ELISA test found that influenza A virus antibodies were present in 60.9% of the horses (173 out of 284).
  • Further testing of the ELISA-positive sera showed equine H3 and H7 subtypes in 60% (21/35) and 20% (7/35) of the horse sera respectively.

Recommendations and Conclusions

  • Based on the high prevalence of EIV, the researchers recommended implementing a national equine influenza surveillance plan. This plan would help monitor the spread and impact of EIV in Nigeria.
  • The researchers also suggested introducing an appropriate EIV control program, which would include preventive measures and treatment options for infected horses.
  • To safeguard Nigeria’s large horse population, adequate quarantine of all imported horses was advised. This step would prevent the spread of EIV from other countries into Nigeria.

The study highlights the extent of EIV infections in Nigeria’s horse population and proposes relevant strategies to control its spread. It emphasizes the importance of regular surveillance and improved biosecurity measures in safeguarding the health of horses on a national scale.

Cite This Article

APA
Meseko CA, Ehizibolo DO, Nwokike EC, Wungak YS. (2016). Serological evidence of equine influenza virus in horse stables in Kaduna, Nigeria. J Equine Sci, 27(3), 99-105. https://doi.org/10.1294/jes.27.99

Publication

Journal of equine science
ISSN: 1340-3516
NlmUniqueID: 9503751
Country: Japan
Language: English
Volume: 27
Issue: 3
Pages: 99-105

Researcher Affiliations

Meseko, Clement A
  • Viral Research Division, National Veterinary Research Institute, P.M.B. 01 Vom, Nigeria.
Ehizibolo, David O
  • Viral Research Division, National Veterinary Research Institute, P.M.B. 01 Vom, Nigeria.
Nwokike, Edith C
  • Equitation Wing, Nigerian Defence Academy, Kaduna, Nigeria.
Wungak, Yiltawe S
  • Viral Research Division, National Veterinary Research Institute, P.M.B. 01 Vom, Nigeria.

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Citations

This article has been cited 4 times.
  1. Gonzalez-Obando J, Jaimes-Dueñez J, Zuluaga-Cabrera A, Forero JE, Diaz A, Rojas-Arbeláez C, Ruiz-Saenz J. Seroprevalence of Equine Influenza Virus Antibodies in Horses from Four Localities in Colombia. Viruses 2025 Jul 16;17(7).
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