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Home / Equine Research Bank / Can J Vet Res / Sex does not influence serum osteocalcin levels in standardb...
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire1992; 56(4); 379-381;

Sex does not influence serum osteocalcin levels in standardbred horses of different ages.

Abstract: The influence of sex on serum osteocalcin levels was studied in 99 Standardbred horses, 52 males and 47 females. The age varied between the day of birth and five years old. A significant inverse correlation (r = -0.87, p 0.05). When the subjects were divided into five age groups of six months or less, 6 to 18, 18 to 24, 24 to 36 and between 36 and 60 months, no significant influence of sex was noted. A predictive model for serum osteocalcin levels (y = 52.19 - 0.026 age in days, r2 = 0.76) for Standardbred horses aged between the day of birth and five years is described.
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Publication Date: 1992-10-01 PubMed ID: 1477808PubMed Central: PMC1263574
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  • Journal Article
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  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research studies the correlation between sex and serum osteocalcin levels in Standardbred horses aged up to five years, and concludes that sex does not affect these levels, though they do decrease with age.

Overview of the Study

  • The study focuses on determining whether sex influences serum osteocalcin levels in Standardbred horses ranging in age from day of birth up to five years.
  • A significant inverse correlation was found between the age of the horse and its serum osteocalcin level—meaning as the horse’s age increased, its osteocalcin level decreased. The correlation coefficient was -0.87, hinting at a strong negative correlation, and it was statistically significant with a p-value less than 0.01.
  • The researchers tested the hypothesis that the horse’s sex might influence their serum osteocalcin levels, but no such influence was found. The p-value was above 0.05, indicating that any observed differences would be likely to arise by chance.
  • The horses were divided into five different age groups: less than or equal to six months, 6 to 18 months, 18 to 24 months, 24 to 36 months, and 36 to 60 months; but even within these groups, no significant impact of sex on osteocalcin levels was observed.

Predictive Model

  • The researchers suggested a predictive model to forecast the serum osteocalcin levels in Standardbred horses. This model was derived using the data collected in this study about the age and osteocalcin levels of the horses.
  • According to the model, y = 52.19 – 0.026 x age in days, where ‘y’ denotes the predicted osteocalcin level. The coefficient of determination (r2) of this model was 0.76, suggesting that about 76% of the variation in the osteocalcin levels can be explained by the age of the horses, based on this research’s data.

Conclusion from the Research

  • The study concluded that sex does not influence serum osteocalcin levels in Standardbred horses aged up to five years. However, the osteocalcin levels decrease as the horse ages, and this decrease can be quite accurately predicted using the study’s model.

Cite This Article

APA
Lepage OM, Marcoux M, Tremblay A, Dumas G. (1992). Sex does not influence serum osteocalcin levels in standardbred horses of different ages. Can J Vet Res, 56(4), 379-381.

Publication

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire
ISSN: 0830-9000
NlmUniqueID: 8607793
Country: Canada
Language: English
Volume: 56
Issue: 4
Pages: 379-381

Researcher Affiliations

Lepage, O M
  • Département de Médecine, Faculté de Médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec.
Marcoux, M
    Tremblay, A
      Dumas, G

        MeSH Terms

        • Aging / blood
        • Animals
        • Breeding
        • Female
        • Horses / blood
        • Male
        • Osteocalcin / blood
        • Radioimmunoassay
        • Reference Values
        • Regression Analysis
        • Sex Characteristics

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        Citations

        This article has been cited 1 times.
        1. Bourebaba L, Röcken M, Marycz K. Osteochondritis dissecans (OCD) in Horses - Molecular Background of its Pathogenesis and Perspectives for Progenitor Stem Cell Therapy. Stem Cell Rev Rep 2019 Jun;15(3):374-390.
          doi: 10.1007/s12015-019-09875-6pubmed: 30796679google scholar: lookup
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