Sparse evidence for equine or avian influenza virus infections among Mongolian adults with animal exposures.
Abstract: In recent years, Mongolia has experienced recurrent epizootics of equine influenza virus (EIV) among its 2·1 million horses and multiple incursions of highly pathogenic avian influenza (HPAI) virus via migrating birds. No human EIV or HPAI infections have been reported. In 2009, 439 adults in Mongolia were enrolled in a population-based study of zoonotic influenza transmission. Enrollment sera were examined for serological evidence of infection with nine avian, three human, and one equine influenza virus strains. Seroreactivity was sparse among participants suggesting little human risk of zoonotic influenza infection.
© 2013 John Wiley & Sons Ltd.
Publication Date: 2013-08-13 PubMed ID: 23941547PubMed Central: PMC4634246DOI: 10.1111/irv.12148Google Scholar: Lookup
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- Journal Article
- Research Support
- American Recovery and Reinvestment Act
- Research Support
- N.I.H.
- Extramural
- Research Support
- U.S. Gov't
- Non-P.H.S.
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This study investigates the potential infection of horse or bird influenza virus among adults in Mongolia who have exposure to animals. Despite recurrent incidents of equine influenza and highly pathogenic avian influenza in the country, the researchers found scant evidence of humans becoming infected with these animal strains of the flu.
Context
- The research was carried out in Mongolia, a country that over recent years has seen outbreaks of equine influenza virus (EIV) in its horse population, and the intrusion of highly pathogenic avian influenza (HPAI) via migratory birds.
- Despite these outbreaks, there have been no reported cases of humans contracting these types of influenza. This study was designed to further investigate that observation.
Methodology
- In 2009, 439 Mongolian adults were enrolled in the study, which aimed to investigate the transmission of zoonotic influenza, or influenza transmitted to humans from animals.
- The serum of the study participants was tested for evidence of infection from a variety of influenza strains. Specifically, nine differing avian strains, three standard human strains, and one equine strain.
Findings
- The results showed limited reactivity to the influenza strains in the serum samples of the participants.
- The implications of this limited seroreactivity suggests that there is a low risk of zoonotic influenza infection among humans, even in areas where outbreaks occur among animal populations.
Significance
- This study provides valuable insights into the limits of zoonotic transmission of influenza strains. The findings are particularly relevant for regions where human populations live in close proximity to large numbers of animals.
- Understanding zoonotic transmission patterns can help public health authorities develop effective measures to mitigate the risk posed by new influenza strains arising from zoonotic sources.
Cite This Article
APA
Khurelbaatar N, Krueger WS, Heil GL, Darmaa B, Ulziimaa D, Tserennorov D, Baterdene A, Anderson BD, Gray GC.
(2013).
Sparse evidence for equine or avian influenza virus infections among Mongolian adults with animal exposures.
Influenza Other Respir Viruses, 7(6), 1246-1250.
https://doi.org/10.1111/irv.12148 Publication
Researcher Affiliations
- Mongolian Association for Infectious Diseases Researchers, Ulaanbaatar, Mongolia.
MeSH Terms
- Adolescent
- Adult
- Aged
- Animals
- Antibodies, Viral / blood
- Birds
- Female
- Horses
- Humans
- Influenza in Birds / transmission
- Influenza, Human / epidemiology
- Influenza, Human / virology
- Male
- Middle Aged
- Mongolia / epidemiology
- Orthomyxoviridae / immunology
- Orthomyxoviridae Infections / transmission
- Seroepidemiologic Studies
- Young Adult
- Zoonoses / epidemiology
- Zoonoses / transmission
Grant Funding
- R01 AI068803 / NIAID NIH HHS
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Citations
This article has been cited 8 times.- Gonzalez-Obando J, Forero JE, Zuluaga-Cabrera AM, Ruiz-Saenz J. Equine Influenza Virus: An Old Known Enemy in the Americas.. Vaccines (Basel) 2022 Oct 14;10(10).
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