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Veterinary surgery : VS1989; 18(6); 415-423; doi: 10.1111/j.1532-950x.1990.tb01116.x

Survival after small intestine resection and anastomosis in horses.

Abstract: The authors examined factors influencing survival in 140 horses that recovered from anesthesia after small intestinal resection between 1968 and 1986, using Kaplan-Meier estimated survival curves and the Cox proportional hazards regression model. Seventy-two horses (51%) died during the initial postoperative period, 19 horses (14%) died after discharge from the hospital, 33 horses (24%) were alive, and 16 horses (11%) were classified as censored. Mean age at surgery was 8 years. Horses 15 years of age or older, Arabians and Stallions, were overrepresented in the hospital population. The most common reason for resection was strangulation of bowel through a mesenteric rent. The mean and 50% median survival times were 1540 and 27 days, respectively. Horses admitted after January 1, 1980, had a significantly longer survival than those admitted before that time. Survival was longer after anastomosis of two small intestinal segments than after anastomosis of a small intestinal segment to the cecum; however, the length of bowel resected and the method of anastomosis had no demonstrable influence on survival. Of the variables studied, the heart rates at presentation and 24 hours after surgery were the most accurate predictors of survival.
Publication Date: 1989-11-01 PubMed ID: 2603371DOI: 10.1111/j.1532-950x.1990.tb01116.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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The research article examines specific influences on survival rates in horses that underwent small intestine surgery between 1968 and 1986. The factors observed were variables like age, breed, reason for surgery, surgery type, and heart rate.

Objective and Methodology

  • The researchers aimed to understand the survival rates in horses after undergoing a small intestinal resection and how different factors influence these outcomes.
  • They used data from 140 horses that had undergone this type of surgery and studied the animals over a considerable period of time, from 1968 to 1986.
  • The study analysis applied two primary statistical methods, Kaplan-Meier estimated survival curves, and the Cox proportional hazards regression model.
  • Various factors such as age, breed, gender, reason for surgery, year of admission, length of bowel resected, method of anastomosis, and heart rates at admission and 24 hours post-surgery were taken into account.

Findings

  • The study found a mortality rate of 65%, further classified into 51% that died during the postoperative period and 14% that died after being discharged from the hospital.
  • The mean and 50% median survival times post-surgery were calculated as 1540 days and 27 days respectively.
  • Horses that were 15 years or older, of Arabian breed, or were stallions, had a higher risk of hospital admission post-surgery.
  • The most common reason requiring intestine surgery was observed to be strangulation of the bowel through a tear in the thin tissue connecting the intestines (mesenteric rent).
  • It was also deduced that horses admitted post-1980 had a significantly longer survival than those admitted prior to this year.
  • The type of surgical intervention also affected the survival rates. Survival was longer after anastomosis (joining of two small intestine sections) than after joining a small intestinal segment to the cecum (a part of the large intestine).
  • However, the length of bowel resected and the method of anastomosis did not significantly influence survival.
  • Of all the variables observed, heart rates at presentation and 24 hours post-surgery were found to be the most accurate predictors of survival.

Conclusion

  • The research concluded that the survival of horses post a small intestine surgery is influenced by several factors, which include the horse’s age, breed, reason for surgery, type of surgery, year of operation, and heart rates during admission and post-surgery.
  • This research contributes to veterinary medicine by aiding in better prediction and planning for the post-operative care and survival prediction of horses undergoing such surgeries.

Cite This Article

APA
MacDonald MH, Pascoe JR, Stover SM, Meagher DM. (1989). Survival after small intestine resection and anastomosis in horses. Vet Surg, 18(6), 415-423. https://doi.org/10.1111/j.1532-950x.1990.tb01116.x

Publication

ISSN: 0161-3499
NlmUniqueID: 8113214
Country: United States
Language: English
Volume: 18
Issue: 6
Pages: 415-423

Researcher Affiliations

MacDonald, M H
  • Veterinary Medical Teaching Hospital, Davis, California.
Pascoe, J R
    Stover, S M
      Meagher, D M

        MeSH Terms

        • Age Factors
        • Anastomosis, Surgical / veterinary
        • Animals
        • Breeding
        • Chi-Square Distribution
        • Female
        • Horses / surgery
        • Intestine, Small / surgery
        • Male
        • Prognosis
        • Retrospective Studies
        • Sex Factors

        Citations

        This article has been cited 8 times.
        1. Matthews LB, Sanz M, Sellon DC. Long-term outcome after colic surgery: retrospective study of 106 horses in the USA (2014-2021). Front Vet Sci 2023;10:1235198.
          doi: 10.3389/fvets.2023.1235198pubmed: 37859945google scholar: lookup
        2. Bardell D, Rocchigiani G, Ressel L, Milner P. Histological Evaluation of Resected Tissue as a Predictor of Survival in Horses with Strangulating Small Intestinal Disease. Animals (Basel) 2023 Aug 26;13(17).
          doi: 10.3390/ani13172715pubmed: 37684979google scholar: lookup
        3. Stöckle SD, Kannapin DA, Kauter AML, Lübke-Becker A, Walther B, Merle R, Gehlen H. A Pilot Randomised Clinical Trial Comparing a Short-Term Perioperative Prophylaxis Regimen to a Long-Term Standard Protocol in Equine Colic Surgery. Antibiotics (Basel) 2021 May 16;10(5).
          doi: 10.3390/antibiotics10050587pubmed: 34065712google scholar: lookup
        4. Sharifi K, Mostaghni K, Maleki M, Badiei K. Ischaemia/reperfusion injury in experimentally induced abomasal volvulus in sheep. Vet Res Commun 2007 Jul;31(5):575-90.
          doi: 10.1007/s11259-007-3450-5pubmed: 17225087google scholar: lookup
        5. Mirza MH, Oliver JL, Seahorn TL, Hosgood G, Moore RM. Detection and comparison of nitric oxide in clinically normal horses and those with naturally acquired small intestinal strangulation obstruction. Can J Vet Res 1999 Oct;63(4):230-40.
          pubmed: 10534001
        6. Grulke S, Benbarek H, Caudron I, Deby-Dupont G, Mathy-Hartert M, Farnir F, Deby C, Lamy M, Serteyn D. Plasma myeloperoxidase level and polymorphonuclear leukocyte activation in horses suffering from large intestinal obstruction requiring surgery: preliminary results. Can J Vet Res 1999 Apr;63(2):142-7.
          pubmed: 10369573
        7. Thomas HL, Zaruby JF, Smith CL, Livesey MA. Postcastration eventration in 18 horses: the prognostic indicators for long-term survival (1985-1995). Can Vet J 1998 Dec;39(12):764-8.
          pubmed: 9861501
        8. Singer ER, Livesey MA, Barker IK, Hurtig MB, Conlon PD. Development of a laboratory animal model of postoperative small intestinal adhesion formation in the rabbit. Can J Vet Res 1996 Oct;60(4):296-304.
          pubmed: 8904666