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Veterinary journal (London, England : 1997)2012; 194(3); 338-342; doi: 10.1016/j.tvjl.2012.04.024

Tendon structure changes after maximal exercise in the Thoroughbred horse: use of ultrasound tissue characterisation to detect in vivo tendon response.

Abstract: Investigations into the response of the superficial digital flexor tendon (SDFT) of the Thoroughbred horse to mechanical stimuli have been limited to in vitro cell culture studies focused primarily on gene expression of critical matrix proteins. It is uncertain how well in vitro outcomes translate to the tendon of the horse during exercise. The current study examined changes in tendon structure in response to maximal exercise using ultrasound tissue characterisation (UTC) to scan the SDFT prior to and after competitive racing. UTC uses contiguous transverse ultrasound images to assess the dynamics of the echopattern, which has a close relationship with changes in the 3-D ultra-structure of the tendon. Using UTC, it was possible to detect subtle changes in the dynamics of the echopattern, with a reduction in pixels that represent aligned and integer collagen tendon bundles on days 1 and 2 post-race when compared to pre-race (P<0.05). The echopattern of these tendons returned to baseline on day 3. This change in echopattern was not seen in control horses. It was concluded that short-term changes in the SDFT following maximal exercise could be detected using UTC.
Copyright © 2012 Elsevier Ltd. All rights reserved.
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Publication Date: 2012-06-01 PubMed ID: 22658820DOI: 10.1016/j.tvjl.2012.04.024Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research study explores how intense exercise affects the tendon structure of Thoroughbred horses. Utilizing ultrasound tissue characterization, preliminary findings suggest significant and temporary structural changes in the tendon post-race, not observed in inactive horses.

Study Objective and Methodology

The study’s primary focus is to understand how the Superficial Digital Flexor Tendon (SDFT), a crucial tendon in Thoroughbred horses, responds to strenuous exercise such as competitive racing. Previous research had been limited to laboratory-based cell culture studies examining genetic expression in vital matrix proteins, with the real-world applicability of this research being questionable.

To evaluate SDFT changes more accurately during exercise, this study employed Ultrasound Tissue Characterisation (UTC):

  • UTC is a technology that uses a sequence of transverse ultrasound images to study the dynamics of the echopattern, an echo from an ultrasound scan that reflects the internal structures of the tendon.
  • The changes in the 3-D ultra-structure of the tendon directly correlate with the dynamics of the echopattern.
  • The researchers performed UTC scans of the SDFT both pre-race and post-race to pick up any significant changes.

Results and Conclusion

Through UTC, the researchers identified subtle but statistically significant changes in the echopattern dynamics which indicated alterations in the tendon structure:

  • There was a measured decrease in the pixels representing aligned and integer collagen tendon bundles on the first and second days post-race, which indicates some form of disruption in the tendon structure.
  • The echopattern and, consequently, the tendon structure returned to normal by the third day post-race, suggesting that the changes are short-term and reversible.
  • In inactive horses (the control group), these changes were not observed, indicating that these disruptions are associated with the strain of maximal exercise.

In conclusion, this study established that short-term changes in the SDFT’s structure following intense exercise could be detected using UTC. This means it’s possible to study the in vivo tendon response in horses, contributing to our understanding of how exercise affects tendon health and potentially aiding in the prevention of race-related injuries.

Cite This Article

APA
Docking SI, Daffy J, van Schie HT, Cook JL. (2012). Tendon structure changes after maximal exercise in the Thoroughbred horse: use of ultrasound tissue characterisation to detect in vivo tendon response. Vet J, 194(3), 338-342. https://doi.org/10.1016/j.tvjl.2012.04.024

Publication

Veterinary journal (London, England : 1997)
ISSN: 1532-2971
NlmUniqueID: 9706281
Country: England
Language: English
Volume: 194
Issue: 3
Pages: 338-342
PII: S1090-0233(12)00179-7

Researcher Affiliations

Docking, S I
  • School of Physiotherapy, Monash University, Peninsula Campus, McMahons Road, Frankston 3199, Australia. sean.docking@monash.edu
Daffy, J
    van Schie, H T M
      Cook, J L

        MeSH Terms

        • Animals
        • Female
        • Horses / physiology
        • Male
        • Physical Conditioning, Animal
        • Species Specificity
        • Tendons / diagnostic imaging
        • Tendons / physiology
        • Ultrasonography / methods
        • Ultrasonography / veterinary

        Citations

        This article has been cited 16 times.
        1. O' Brien C, Pegg J. A Preliminary Investigation into Ridden Water Submersion Training as an Adjunct to Current Condition Training Protocols in Performance Horses. Animals (Basel) 2021 Sep 7;11(9).
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        2. Masci L, Neal BS, Wynter Bee W, Spang C, Alfredson H. Achilles Scraping and Plantaris Tendon Removal Improves Pain and Tendon Structure in Patients with Mid-Portion Achilles Tendinopathy-A 24 Month Follow-Up Case Series. J Clin Med 2021 Jun 18;10(12).
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        3. Leclerc M, Gauthier C, Brosseau R, Desmeules F, Gagnon DH. Changes to Biceps and Supraspinatus Tendons in Response to a Progressive Maximal Treadmill-Based Propulsion Aerobic Fitness Test in Manual Wheelchair Users: A Quantitative Musculoskeletal Ultrasound Study. Rehabil Res Pract 2021;2021:6663575.
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        4. Logan AA, Nielsen BD. Training Young Horses: The Science behind the Benefits. Animals (Basel) 2021 Feb 9;11(2).
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        5. Masci L, Alfredson H, Neal B, Wynter Bee W. Ultrasound-guided tendon debridement improves pain, function and structure in persistent patellar tendinopathy: short term follow-up of a case series. BMJ Open Sport Exerc Med 2020;6(1):e000803.
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        6. Aiyegbusi A, Tella B, Okeke C. Lower Limb Biomechanical Variables Are Indicators of the Pattern of Presentation of Patella Tendinopathy in Elite African Basketball and Volleyball Players. Rev Bras Ortop (Sao Paulo) 2019 Sep;54(5):540-548.
          doi: 10.1055/s-0039-1693743pubmed: 31736522google scholar: lookup
        7. Docking SI, Cook J. How do tendons adapt? Going beyond tissue responses to understand positive adaptation and pathology development: A narrative review. J Musculoskelet Neuronal Interact 2019 Sep 1;19(3):300-310.
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        8. Rudavsky A, Cook J, Magnusson SP, Kjaer M, Docking S. Characterising the proximal patellar tendon attachment and its relationship to skeletal maturity in adolescent ballet dancers. Muscles Ligaments Tendons J 2017 Apr-Jun;7(2):306-314.
          doi: 10.11138/mltj/2017.7.2.306pubmed: 29264342google scholar: lookup
        9. Geburek F, Roggel F, van Schie HTM, Beineke A, Estrada R, Weber K, Hellige M, Rohn K, Jagodzinski M, Welke B, Hurschler C, Conrad S, Skutella T, van de Lest C, van Weeren R, Stadler PM. Effect of single intralesional treatment of surgically induced equine superficial digital flexor tendon core lesions with adipose-derived mesenchymal stromal cells: a controlled experimental trial. Stem Cell Res Ther 2017 Jun 5;8(1):129.
          doi: 10.1186/s13287-017-0564-8pubmed: 28583184google scholar: lookup
        10. Geburek F, Gaus M, van Schie HT, Rohn K, Stadler PM. Effect of intralesional platelet-rich plasma (PRP) treatment on clinical and ultrasonographic parameters in equine naturally occurring superficial digital flexor tendinopathies - a randomized prospective controlled clinical trial. BMC Vet Res 2016 Sep 7;12(1):191.
          doi: 10.1186/s12917-016-0826-1pubmed: 27604193google scholar: lookup
        11. Cook JL, Rio E, Purdam CR, Docking SI. Revisiting the continuum model of tendon pathology: what is its merit in clinical practice and research?. Br J Sports Med 2016 Oct;50(19):1187-91.
          doi: 10.1136/bjsports-2015-095422pubmed: 27127294google scholar: lookup
        12. Wong AM, Docking SI, Cook JL, Gaida JE. Does type 1 diabetes mellitus affect Achilles tendon response to a 10 km run? A case control study. BMC Musculoskelet Disord 2015 Nov 10;16:345.
          doi: 10.1186/s12891-015-0803-zpubmed: 26556589google scholar: lookup
        13. Grimaldi A, Mellor R, Hodges P, Bennell K, Wajswelner H, Vicenzino B. Gluteal Tendinopathy: A Review of Mechanisms, Assessment and Management. Sports Med 2015 Aug;45(8):1107-19.
          doi: 10.1007/s40279-015-0336-5pubmed: 25969366google scholar: lookup
        14. Jacobson E, Dart AJ, Mondori T, Horadogoda N, Jeffcott LB, Little CB, Smith MM. Focal experimental injury leads to widespread gene expression and histologic changes in equine flexor tendons. PLoS One 2015;10(4):e0122220.
          doi: 10.1371/journal.pone.0122220pubmed: 25837713google scholar: lookup
        15. Lavagnino M, Wall ME, Little D, Banes AJ, Guilak F, Arnoczky SP. Tendon mechanobiology: Current knowledge and future research opportunities. J Orthop Res 2015 Jun;33(6):813-22.
          doi: 10.1002/jor.22871pubmed: 25763779google scholar: lookup
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