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Lancet (London, England)1948; 2(6525); 451;

The eosinophil cell; studies in horse and camel.

Abstract: This research article investigates the significance of eosinophil cells in horses and camels, focusing on the large granules found in these cells and their similarities to smaller red blood cells. […]
Publication Date: 1948-09-18 PubMed ID: 18881566
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  • Journal Article

Summary

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This research article investigates the significance of eosinophil cells in horses and camels, focusing on the large granules found in these cells and their similarities to smaller red blood cells. The research also explores the origin of these cells in equines and challenges prior objections about related cellular activities.

Investigating Eosinophils in Horses

  • The study began with an examination of horse blood and tissues, due to observations that horse eosinophils contained granules similar in appearance to small red blood cells. The granules in these cells were notably larger than those in other mammals, including humans.
  • Examination revealed that the size of granules varied among cells. Some were as large as a small red blood cell, and the granules left ashes after micro-incineration, as seen in human samples.
  • The gastric and intestinal mucosa of the horse were also studied. The results indicated these are likely locations for eosinophil formation. These cells also seemed to be the source of red blood cells.

Eosinophils and Red Blood Cells in Hervibora & Humans

  • The study also tackled objections related to the role of eosinophils in the secretion of red blood cells both in humans and hervibora. The objections contested that the cells were undergoing phagocytosis and the large cells found in the thyroid gland in humans were a result of an unexplained cellular mechanism.
  • But as per study observations, it was proved that eosinophils indeed secrete red blood cells.

Study of Camel Eosinophils

  • The research then focused on camels, due to their elliptical red blood cells. The aim was to provide a conclusive proof that the granules in eosinophil cells were indeed similar to red blood cells.
  • The camel blood smears showed that all the granules in eosinophils were elliptical, providing strong evidence of their origin.
  • Furthermore, these granules contrasted with the granules of the basophils, which were perfectly circular.

Concluding Observations

  • Due to constraints in obtaining camel tissues, the study couldn’t explore the complete cycle of blood formation in this animal. However, the research suggested that eosinophils could be the mother cells of red blood cells in these animals.
  • This research casts eosinophils in a new light and indicates the need for further investigation to understand their role in red blood cell production.

Cite This Article

APA
DURAN-JORDA F. (1948). The eosinophil cell; studies in horse and camel. Lancet, 2(6525), 451.

Publication

ISSN: 0140-6736
NlmUniqueID: 2985213R
Country: England
Language: English
Volume: 2
Issue: 6525
Pages: 451

Researcher Affiliations

DURAN-JORDA, F

    MeSH Terms

    • Animals
    • Camelus
    • Eosinophils
    • Horses
    • Humans
    • Leukocyte Count

    Citations

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