The pharmacologic basis for the treatment of developmental and acute laminitis.
Abstract: Each horse with laminitis is presented to the veterinarian at a different stage in progression of the condition and with varying severity. The pathogenic timing is often unknown and is difficult to determine. Because timing and severity are related to both the lesion's severity and responsiveness to treatment, these factors are critical to treatment selection and success. It is erroneous to assume that each horse with laminitis should receive each treatment. It is therefore important to ascertain as logically and objectively as possible the pathophysiological stage of development of each horse when it is examined. Therapeutic failure may result from inappropriate interpretation of the clinical signs and pathophysiologic condition of the patient in order to coordinate a treatment regimen.
Publication Date: 1999-09-03 PubMed ID: 10472116DOI: 10.1016/s0749-0739(17)30149-9Google Scholar: Lookup
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Summary
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The research article discusses the importance of properly identifying the stage and severity of laminitis, a common equine condition, in horses to ensure the appropriate pharmacological treatment is applied.
Understanding Laminitis
- Laminitis is a serious condition potentially affecting all breeds of horses. It involves inflammation of the laminar tissue in horses’ hooves, disrupting the blood flow needed for proper foot health.
- The timing and progression of this disease are often challenging to ascertain, making treatment decisions complex.
Importance of Accurate Diagnosis
- The research emphasizes the significance of correctly determining the current stage of the disease in each patient. The development stage and severity of the laminitis directly influence the choice and potential success of the treatment.
- Failures in treatment are often attributed to incorrect interpretation of clinical signs and the horse’s present pathophysiological condition; hence, accurate diagnosis is crucial.
Tailored Treatment Approach
- The paper argues against assuming a one-size-fits-all approach for treating laminitis. Due to the diverse manifestations of this condition in different horses, individualized treatment plans are needed.
- Objective and logical evaluation of each horse’s condition is imperative to determine the most suitable treatment regimen.
Overall, this research advocates for more personalized and accurately tailored treatment strategies for horses suffering from laminitis, highlighting the correlation between the disease’s progression and the effectiveness of the treatment. Effective treatment requires careful and accurate evaluation of the disease stage and severity for each individual equine patient.
Cite This Article
APA
Brumbaugh GW, Sumano López H, Hoyas Sepúlveda ML.
(1999).
The pharmacologic basis for the treatment of developmental and acute laminitis.
Vet Clin North Am Equine Pract, 15(2), 345-362.
https://doi.org/10.1016/s0749-0739(17)30149-9 Publication
Researcher Affiliations
- Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine, Texas A&M University, College Station, USA.
MeSH Terms
- Acute Disease
- Animals
- Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
- Anticoagulants / therapeutic use
- Cardiovascular Agents / therapeutic use
- Foot Diseases / drug therapy
- Foot Diseases / veterinary
- Hoof and Claw
- Horse Diseases / drug therapy
- Horses
- Inflammation / drug therapy
- Inflammation / veterinary
Citations
This article has been cited 1 times.- Aoun R, Charles I, DeRouen A, Takawira C, Lopez MJ. Shoe configuration effects on third phalanx and capsule motion of unaffected and laminitic equine hooves in-situ. PLoS One 2023;18(5):e0285475.
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