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The prevalence of antibodies to Toxoplasma gondii in horses in Changji Hui Autonomous Prefecture, Xinjiang, northwestern China.

Abstract: Toxoplasmosis is a worldwide zoonosis caused by Toxoplasma gondii, which can infect warm-blooded animals and humans. The present study was performed to investigate the seroprevalence of T. gondii in horses in Xinjiang, northwestern China. A total of 637 blood samples were collected from seven regions in Changji Hui Autonomous Prefecture, Xinjiang in 2011 and assayed for T. gondiiantibodies using the modified agglutination test (MAT). Risk factors (age, gender, and region) related to seroprevalence were determined by a multivariate logistic regression analysis. A total of 200 horses (31.4%, 95% CI 27.79-35.00) were seropositive for T. gondii. Age, gender, and region present no association with seroprevalence (p>0.05) in the logistic regression analysis. The results indicated that T. gondii is widely prevalent in horses in Xinjiang, northwestern China, representing a serious threat to animal and human health. Therefore, more careful measures should be performed to control and prevent T. gondii infection in horses from Xinjiang, northwestern China.
Publication Date: 2015-08-28 PubMed ID: 26331867DOI: 10.1590/S1984-29612015050Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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This study aims to analyze the occurrence of Toxoplasma gondii, a parasite that can infect warm-blooded creatures and humans creating a worldwide disease known as toxoplasmosis, in horses within Changji Hui Autonomous Prefecture, in Xinjiang, northwestern China.

Research Methodology

  • The researchers in this study gathered a total of 637 blood samples drawn from horses in seven different areas within Changji Hui Autonomous Prefecture in Xinjiang, during the year 2011.
  • These samples were examined for the presence of T.gondii antibodies using a technique known as the modified agglutination test (MAT).
  • In order to establish any potential risk factors related to the presence of T. gondii, a multivariate logistic regression analysis was carried out, taking into account elements such as the age of the horse, its gender, and the region from which it originated.

Research Findings

  • The results showed that 200 of the 637 horses (31.4%) tested positively for T. gondii antibodies. This finding indicates that these horses had been exposed to the parasite at some point in their lives.
  • Further analysis using logistic regression suggested that the prevalence of T. gondii in horses in this region is not significantly associated with any of the studied risk factors (age, gender or region).
  • This means that the presence of T. gondii in horses in this area of China is widespread and is not limited to specific sub-groups of horses based on age or gender or located in particular regions.

Implications of the Research

  • The findings from this study present significant implications for both animal and human health. The widespread prevalence of the parasite in horses indicates a substantial risk for humans and other warm-blooded animals in the region.
  • This is due to the fact that T. gondii can be transmitted from horses to humans and other animals, posing a risk of toxoplasmosis – a disease that can lead to severe health problems, especially in individuals with weakened immune systems.
  • The study advocates for more rigorous measures to control and prevent T. gondii infections within Xinjiang’s horse population, thereby reducing potential health risks to humans and other animals.

Cite This Article

APA
Wang JL, Zhou DH, Chen J, Liu GX, Pu WB, Liu TY, Qin SY, Yin MY, Zhu XQ. (2015). The prevalence of antibodies to Toxoplasma gondii in horses in Changji Hui Autonomous Prefecture, Xinjiang, northwestern China. Rev Bras Parasitol Vet, 24(3), 298-302. https://doi.org/10.1590/S1984-29612015050

Publication

ISSN: 1984-2961
NlmUniqueID: 9440482
Country: Brazil
Language: English
Volume: 24
Issue: 3
Pages: 298-302
PII: S1984-29612015005015050

Researcher Affiliations

Wang, Jin-Lei
  • State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Gansu Province, Lanzhou, CN.
Zhou, Dong-Hui
  • State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Gansu Province, Lanzhou, CN.
Chen, Jia
  • State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Gansu Province, Lanzhou, CN.
Liu, Guang-Xue
  • State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Gansu Province, Lanzhou, CN.
Pu, Wen-Bing
  • Changji Prefecture Animal Disease Control and Prevention Center, Xinjiang Uygur Autonomous Region, CN.
Liu, Ting-Yu
  • Changji Prefecture Animal Disease Control and Prevention Center, Xinjiang Uygur Autonomous Region, CN.
Qin, Si-Yuan
  • State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Gansu Province, Lanzhou, CN.
Yin, Ming-Yang
  • State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Gansu Province, Lanzhou, CN.
Zhu, Xing-Quan
  • State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Gansu Province, Lanzhou, CN.

MeSH Terms

  • Animals
  • Antibodies, Protozoan / blood
  • China / epidemiology
  • Female
  • Horse Diseases / blood
  • Horse Diseases / epidemiology
  • Horses
  • Male
  • Prevalence
  • Seroepidemiologic Studies
  • Toxoplasma / immunology
  • Toxoplasmosis, Animal / blood
  • Toxoplasmosis, Animal / epidemiology

Citations

This article has been cited 3 times.
  1. Marzok M, Al-Jabr OA, Salem M, Alkashif K, Sayed-Ahmed M, Wakid MH, Kandeel M, Selim A. Seroprevalence and Risk Factors for Toxoplasma gondii Infection in Horses.. Vet Sci 2023 Mar 22;10(3).
    doi: 10.3390/vetsci10030237pubmed: 36977276google scholar: lookup
  2. Stelzer S, Basso W, Benavides Silván J, Ortega-Mora LM, Maksimov P, Gethmann J, Conraths FJ, Schares G. Toxoplasma gondii infection and toxoplasmosis in farm animals: Risk factors and economic impact.. Food Waterborne Parasitol 2019 Jun;15:e00037.
    doi: 10.1016/j.fawpar.2019.e00037pubmed: 32095611google scholar: lookup
  3. Ouslimani SF, Tennah S, Azzag N, Derdour SY, China B, Ghalmi F. Seroepidemiological study of the exposure to Toxoplasma gondii among horses in Algeria and analysis of risk factors.. Vet World 2019 Dec;12(12):2007-2016.