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Home / Equine Research Bank / Equine Vet J / The prevalence of enteric pathogens in diarrhoeic thoroughbr...
Equine veterinary journal1991; 23(6); 405-409; doi: 10.1111/j.2042-3306.1991.tb03751.x

The prevalence of enteric pathogens in diarrhoeic thoroughbred foals in Britain and Ireland.

Abstract: A survey of 77 normal and 326 diarrhoeic foals in Britain and Ireland from 1987 to 1989 revealed a significantly higher prevalence of Group A rotaviruses and Aeromonas hydrophila in diarrhoeic foals. The prevalence of cryptosporidia, potentially pathogenic Escherichia coli, Yersinia enterocolitica and Clostridium perfringens was similar in normal or diarrhoeic foals. Rotaviruses had a similar prevalence in all age groups of scouring foals up to three months of age, with an overall prevalence of 37 per cent among diarrhoeic foals. The number of cases of diarrhoea varied considerably from year to year, but in all three years of the survey rotavirus was a significant pathogen. A comparison of diagnostic tests for rotavirus in the faeces showed electron microscopy (EM) and polyacrylamide gel electrophoresis (PAGE) to have similar sensitivity. The Rotazyme ELISA test kit was found to have the same sensitivity as a combination of EM and PAGE. A. hydrophila had an overall prevalence of 9 per cent among diarrhoeic foals, although its prevalence was higher in some age groups. A. hydrophila has not been established previously as a significant enteric pathogen in foals. Other putative pathogens found at very low prevalence were coronavirus, the putative picobirnavirus, Campylobacter spp. and Salmonella spp. No evidence was found of synergistic effects between rotavirus, cryptosporidia and potentially pathogenic E. coli. Neither coccidia nor non-Group A rotaviruses were found in any of the samples examined.
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Publication Date: 1991-11-01 PubMed ID: 1663866PubMed Central: PMC7185455DOI: 10.1111/j.2042-3306.1991.tb03751.xGoogle Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research conducted from 1987 to 1989 in Britain and Ireland investigated the common cause of diarrhea in foals, tracing it primarily to Group A rotaviruses and Aeromonas hydrophila. These were significantly more prevalent in foals with diarrhea compared to healthy animals, with other potential pathogens showing low prevalence.

About the Study

The researchers undertook a comprehensive survey of equine pathogens. They used samples collected from 77 healthy and 326 diarrheic foals in Britain and Ireland over three years (1987-89). The primary focus was to identify the cause of diarrhea in foals, a common health issue. The analysis included testing for Group A rotaviruses, Aeromonas hydrophila, cryptosporidia, Escherichia coli, Yersinia enterocolitica, and Clostridium perfringens.

Key Findings

  • An increase in Group A rotaviruses and Aeromonas hydrophila was observed in samples from diarrheic foals compared to healthy horses, suggesting these pathogens as likely agents of this condition.
  • The prevalence of cryptosporidia, potentially dangerous variants of Escherichia coli, Yersinia enterocolitica, and Clostridium perfringens remained similar in both healthy and afflicted foals, indicating these pathogens may not be the primary cause of diarrhea in these animals.
  • The prevalence of rotaviruses remained constant across all age groups in foals suffering from diarrhea up to three months of age. The overall rate of prevalence among diarrheic foals was 37 per cent.
  • Yearly variants were observed in the number of diarrhea cases, but the rotavirus remained a significant pathogen throughout the duration of the survey.

Diagnostic Tests

  • The study compared electron microscopy (EM) and polyacrylamide gel electrophoresis (PAGE) as diagnostic tools for identifying rotavirus in feces, concluding both methods had comparable sensitivity while testing.
  • Rotazyme ELISA test kit showed sensitivity equivalent to the combined application of EM and PAGE.

Aeromonas Hydrophila

  • The research uncovered a 9 per cent prevalence of Aeromonas hydrophila among diarrheic foals. In certain age groups, its prevalence was even higher. The study suggests this could make Aeromonas hydrophila a potentially significant pathogen for foals, a fact not previously recognized.

Other Pathogens

  • Pathogens like the coronavirus, Campylobacter spp., picobirnavirus, and the Salmonella spp. were found but at very low prevalence, suggesting a limited role in conditions leading to diarrhea.
  • The study found no supporting evidence for synergistic effects between rotavirus, cryptosporidia and pathogenic variants of E. coli.

Cite This Article

APA
Browning GF, Chalmers RM, Snodgrass DR, Batt RM, Hart CA, Ormarod SE, Leadon D, Stoneham SJ, Rossdale PD. (1991). The prevalence of enteric pathogens in diarrhoeic thoroughbred foals in Britain and Ireland. Equine Vet J, 23(6), 405-409. https://doi.org/10.1111/j.2042-3306.1991.tb03751.x

Publication

Equine veterinary journal
ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 23
Issue: 6
Pages: 405-409

Researcher Affiliations

Browning, G F
  • Moredun Research Institute, Edinburgh.
Chalmers, R M
    Snodgrass, D R
      Batt, R M
        Hart, C A
          Ormarod, S E
            Leadon, D
              Stoneham, S J
                Rossdale, P D

                  MeSH Terms

                  • Aeromonas / isolation & purification
                  • Animals
                  • Breeding
                  • Clostridium Infections / epidemiology
                  • Clostridium Infections / microbiology
                  • Clostridium Infections / veterinary
                  • Clostridium perfringens / isolation & purification
                  • Cryptosporidiosis / epidemiology
                  • Cryptosporidiosis / parasitology
                  • Diarrhea / epidemiology
                  • Diarrhea / microbiology
                  • Diarrhea / veterinary
                  • Escherichia coli Infections / epidemiology
                  • Escherichia coli Infections / microbiology
                  • Escherichia coli Infections / veterinary
                  • Feces / microbiology
                  • Gram-Negative Bacterial Infections / epidemiology
                  • Gram-Negative Bacterial Infections / microbiology
                  • Gram-Negative Bacterial Infections / veterinary
                  • Horse Diseases / epidemiology
                  • Horse Diseases / microbiology
                  • Horses
                  • Ireland / epidemiology
                  • Prevalence
                  • Rotavirus / isolation & purification
                  • Rotavirus / ultrastructure
                  • Rotavirus Infections / epidemiology
                  • Rotavirus Infections / microbiology
                  • Rotavirus Infections / veterinary
                  • Seasons
                  • United Kingdom / epidemiology
                  • Yersinia Infections / epidemiology
                  • Yersinia Infections / microbiology
                  • Yersinia Infections / veterinary
                  • Yersinia enterocolitica / isolation & purification

                  References

                  This article includes 33 references
                  1. Baker JC, Ames TR. Total parenteral nutritional therapy of a foal with diarrhoea from which parvovirus-like particles were identified.. Equine Vet J 1987 Jul;19(4):342-4.
                    pmc: PMC7199473pubmed: 3040389doi: 10.1111/j.2042-3306.1987.tb01429.xgoogle scholar: lookup
                  2. Barker IK, Remmler O. The endogenous development of Eimeria leuckarti in ponies.. J Parasitol 1972 Feb;58(1):112-22.
                    pubmed: 5062456
                  3. Bass EP, Sharpee RL. Coronavirus and gastroenteritis in foals.. Lancet 1975 Oct 25;2(7939):822.
                    pmc: PMC7135031pubmed: 78197doi: 10.1016/s0140-6736(75)80058-4google scholar: lookup
                  4. Batt RM, Embaye H, Hunt J, Hart CA. Ultrastructural damage to equine intestinal epithelium induced by enteropathogenic Escherichia coli.. Equine Vet J 1989 Sep;21(5):373-5.
                    pubmed: 2673761doi: 10.1111/j.2042-3306.1989.tb02695.xgoogle scholar: lookup
                  5. Burke V, Gracey M, Robinson J, Peck D, Beaman J, Bundell C. The microbiology of childhood gastroenteritis: Aeromonas species and other infective agents.. J Infect Dis 1983 Jul;148(1):68-74.
                    pubmed: 6886488doi: 10.1093/infdis/148.1.68google scholar: lookup
                  6. Coleman SU, Klei TR, French DD, Chapman MR, Corstvet RE. Prevalence of Cryptosporidium sp in equids in Louisiana.. Am J Vet Res 1989 Apr;50(4):575-7.
                    pubmed: 2712425
                  7. Conner ME, Darlington RW. Rotavirus infection in foals.. Am J Vet Res 1980 Oct;41(10):1699-703.
                    pubmed: 6261616
                  8. Dickie CW, Klinkerman DL, Petrie RJ. Enterotoxemia in two foals.. J Am Vet Med Assoc 1978 Aug 1;173(3):306-7.
                    pubmed: 211108
                  9. Durham PJ, Stevenson BJ, Farquharson BC. Rotavirus and coronavirus associated diarrhoea in domestic animals.. N Z Vet J 1979 Mar;27(3):30-2.
                    pubmed: 221870doi: 10.1080/00480169.1979.34595google scholar: lookup
                  10. Dwyer RM, Powell D, Lyons E, Donahue JM, Roberts AW, Osborne M. The aetiology of infectious diarrhoea in Thoroughbred foals in central Kentucky. Equine vet. J. Suppl. 5, 59–60 (1988).
                    pubmed: 0
                  11. el-Ghorr AA, Snodgrass DR, Scott FM. Evaluation of an immunogold electron microscopy technique for detecting bovine coronavirus.. J Virol Methods 1988 Mar-Apr;19(3-4):215-23.
                    pmc: PMC7119617pubmed: 2836459doi: 10.1016/0166-0934(88)90016-xgoogle scholar: lookup
                  12. Fletcher JN, Saunders JR, Batt RM, Embaye H, Getty B, Hart CA. Attaching effacement of the rabbit enterocyte brush border is encoded on a single 96.5-kilobase-pair plasmid in an enteropathogenic Escherichia coli O111 strain.. Infect Immun 1990 May;58(5):1316-22.
                    pmc: PMC258626pubmed: 2182541doi: 10.1128/iai.58.5.1316-1322.1990google scholar: lookup
                  13. Flewett TH, Bryden AS, Davies H. Letter: Virus diarrhoea in foals and other animals.. Vet Rec 1975 May 24;96(21):JMM.
                    pubmed: 1136110
                  14. Gatti MS, de Castro AF, Ferraz MM, Fialho AM, Pereira HG. Viruses with bisegmented double-stranded RNA in pig faeces.. Res Vet Sci 1989 Nov;47(3):397-8.
                    pubmed: 2687991
                  15. Gillespie J, Kalica A, Conner M, Schiff E, Barr M, Holmes D, Frey M. The isolation, propagation and characterization of tissue-cultured equine rotaviruses.. Vet Microbiol 1984 Feb;9(1):1-14.
                    pubmed: 6326375doi: 10.1016/0378-1135(84)90074-9google scholar: lookup
                  16. Herbst W, Zschöck M, Hamann HP, Lange H, Weiss R, Danner K, Schliesser T. [The occurrence of rotavirus and fimbriae-bearing E. coli types in foals with diarrhea].. Berl Munch Tierarztl Wochenschr 1987 Nov 1;100(11):364-6.
                    pubmed: 2892483
                  17. Herring AJ, Inglis NF, Ojeh CK, Snodgrass DR, Menzies JD. Rapid diagnosis of rotavirus infection by direct detection of viral nucleic acid in silver-stained polyacrylamide gels.. J Clin Microbiol 1982 Sep;16(3):473-7.
                    pmc: PMC272392pubmed: 6182158doi: 10.1128/jcm.16.3.473-477.1982google scholar: lookup
                  18. Higgins WP, Gillespie SH, Schiff EI, Pennow NN, Tanneberger MJ. Infectivity and immunity studies in foals with cell culture‐propagated equine rotaviruses. Proc. 5th Int. Conf. Equine Inf. Dis. pp 241–247 (1988).
                  19. Imagawa H, Wada R, Hirasawa K, Akiyama Y, Oda T. Isolation of equine rotavirus in cell cultures from foals with diarrhea.. Nihon Juigaku Zasshi 1984 Feb;46(1):1-9.
                    pubmed: 6330417doi: 10.1292/jvms1939.46.1google scholar: lookup
                  20. Imagawa H, Wada R, Kamada M, Kumanomido T, Fukunaga Y, Hirasawa K. Experimental infection of equine rotaviruses in foals. Bull. Equine Res. Inst. 21, 65–71 (1984b).
                  21. Jones RL, Adney WS, Alexander AF, Shideler RK, Traub-Dargatz JL. Hemorrhagic necrotizing enterocolitis associated with Clostridium difficile infection in four foals.. J Am Vet Med Assoc 1988 Jul 1;193(1):76-9.
                    pubmed: 3262102
                  22. Kanitz CL. Identification of an equine rotavirus as a cause of neonatal foal diarrhoea. Proc. Am. Equine Pract. Ass. 22, 155–165 (1976).
                  23. Myers LL, Shoop DS, Byars TD. Diarrhea associated with enterotoxigenic Bacteroides fragilis in foals.. Am J Vet Res 1987 Nov;48(11):1565-7.
                    pubmed: 3434899
                  24. Snodgrass DR. Evaluation of a combined rotavirus and enterotoxigenic Escherichia coli vaccine in cattle.. Vet Rec 1986 Jul 12;119(2):39-42.
                    pubmed: 3018989doi: 10.1136/vr.119.2.39google scholar: lookup
                  25. Sokal RR, Rohlf FJ. Analysis of frequencies. Biometry 2nd edn, W. H. Freeman and Company, New York, pp 691–778 (1981).
                  26. Strickland KL, Lenihan P, O'Connor MG, Condon JC. Diarrhoea in foals associated with rotavirus.. Vet Rec 1982 Oct 30;111(18):421.
                    pubmed: 7147670doi: 10.1136/vr.111.18.421google scholar: lookup
                  27. Studdert MJ, Mason RW, Patten BE. Rotavirus diarrhoea of foals.. Aust Vet J 1978 Jul;54(7):363-4.
                    pubmed: 213048doi: 10.1111/j.1751-0813.1978.tb02499.xgoogle scholar: lookup
                  28. Studdert MJ, Blackney MH. Isolation of an adenovirus antigenically distinct from equine adenovirus type 1 from diarrheic foal feces.. Am J Vet Res 1982 Mar;43(3):543-4.
                    pubmed: 6176153
                  29. Traub-Dargatz JL, Gay CC, Evermann JF, Ward AC, Zeglen ME, Gallina AM, Salman MD. Epidemiologic survey of diarrhea in foals.. J Am Vet Med Assoc 1988 Jun 1;192(11):1553-6.
                    pubmed: 3410771
                  30. Tzipori S, Hayes J, Sims L, Withers M. Streptococcus durans: an unexpected enteropathogen of foals.. J Infect Dis 1984 Oct;150(4):589-93.
                    pubmed: 6386998doi: 10.1093/infdis/150.4.589google scholar: lookup
                  31. Tzipori S, Withers M, Hayes J, Robins-Browne R, Ward KL. Attachment of E. coli-bearing K88 antigen to equine brush-border membranes.. Vet Microbiol 1984 Oct;9(6):561-70.
                    pubmed: 6150571doi: 10.1016/0378-1135(84)90018-xgoogle scholar: lookup
                  32. Tzipori S. The relative importance of enteric pathogens affecting neonates of domestic animals.. Adv Vet Sci Comp Med 1985;29:103-206.
                    pubmed: 2868628
                  33. Urquhart K. Diarrhoea in foals. Equine Pract. 3, 22–30 (1981).

                  Citations

                  This article has been cited 40 times.
                  1. Uzal FA, Arroyo LG, Navarro MA, Gomez DE, Asín J, Henderson E. Bacterial and viral enterocolitis in horses: a review. J Vet Diagn Invest 2022 May;34(3):354-375.
                    doi: 10.1177/10406387211057469pubmed: 34763560google scholar: lookup
                  2. Goodman-Davis R, Figurska M, Cywinska A. Gut Microbiota Manipulation in Foals-Naturopathic Diarrhea Management, or Unsubstantiated Folly?. Pathogens 2021 Sep 4;10(9).
                    doi: 10.3390/pathogens10091137pubmed: 34578169google scholar: lookup
                  3. Nemoto M, Matsumura T. Equine rotavirus infection. J Equine Sci 2021 Mar;32(1):1-9.
                    doi: 10.1294/jes.32.1pubmed: 33776534google scholar: lookup
                  4. Snodgrass DR. Foal rotavirus - can we learn anything from calf scour?. Equine Vet Educ 1992 Oct;4(5):245-247.
                    doi: 10.1111/j.2042-3292.1992.tb01630.xpubmed: 32313403google scholar: lookup
                  5. Mallicote M, House AM, Sanchez LC. A review of foal diarrhoea from birth to weaning. Equine Vet Educ 2012 Apr;24(4):206-214.
                    doi: 10.1111/j.2042-3292.2011.00358.xpubmed: 32313387google scholar: lookup
                  6. Malik YS, Sircar S, Saurabh S, Kattoor JJ, Singh R, Ganesh B, Ghosh S, Dhama K, Singh RK. Epidemiologic Status of Picobirnavirus in India, A Less Explored Viral Disease. Open Virol J 2018;12:99-109.
                    doi: 10.2174/1874357901812010099pubmed: 30288198google scholar: lookup
                  7. Duraisamy R, Akiana J, Davoust B, Mediannikov O, Michelle C, Robert C, Parra HJ, Raoult D, Biagini P, Desnues C. Detection of novel RNA viruses from free-living gorillas, Republic of the Congo: genetic diversity of picobirnaviruses. Virus Genes 2018 Apr;54(2):256-271.
                    doi: 10.1007/s11262-018-1543-6pubmed: 29476397google scholar: lookup
                  8. Oliver-Espinosa O. Foal Diarrhea: Established and Postulated Causes, Prevention, Diagnostics, and Treatments. Vet Clin North Am Equine Pract 2018 Apr;34(1):55-68.
                    doi: 10.1016/j.cveq.2017.11.003pubmed: 29395727google scholar: lookup
                  9. Olivo G, Lucas TM, Borges AS, Silva RO, Lobato FC, Siqueira AK, da Silva Leite D, Brandão PE, Gregori F, de Oliveira-Filho JP, Takai S, Ribeiro MG. Enteric Pathogens and Coinfections in Foals with and without Diarrhea. Biomed Res Int 2016;2016:1512690.
                    doi: 10.1155/2016/1512690pubmed: 28116290google scholar: lookup
                  10. Reichel MP, Lanyon SR, Hill FI. Moving past serology: Diagnostic options without serum. Vet J 2016 Sep;215:76-81.
                    doi: 10.1016/j.tvjl.2016.04.010pubmed: 27160006google scholar: lookup
                  11. Ganesh B, Masachessi G, Mladenova Z. Animal picobirnavirus. Virusdisease 2014;25(2):223-38.
                    doi: 10.1007/s13337-014-0207-ypubmed: 25674589google scholar: lookup
                  12. Matthijnssens J, Ons E, De Coster S, Conceição-Neto N, Gryspeerdt A, Van Ranst M, Raue R. Molecular characterization of equine rotaviruses isolated in Europe in 2013: implications for vaccination. Vet Microbiol 2015 Mar 23;176(1-2):179-85.
                    doi: 10.1016/j.vetmic.2015.01.011pubmed: 25637313google scholar: lookup
                  13. Woo PC, Lau SK, Teng JL, Tsang AK, Joseph M, Wong EY, Tang Y, Sivakumar S, Bai R, Wernery R, Wernery U, Yuen KY. Metagenomic analysis of viromes of dromedary camel fecal samples reveals large number and high diversity of circoviruses and picobirnaviruses. Virology 2014 Dec;471-473:117-25.
                    doi: 10.1016/j.virol.2014.09.020pubmed: 25461537google scholar: lookup
                  14. Malik YS, Kumar N, Sharma K, Dhama K, Shabbir MZ, Ganesh B, Kobayashi N, Banyai K. Epidemiology, phylogeny, and evolution of emerging enteric Picobirnaviruses of animal origin and their relationship to human strains. Biomed Res Int 2014;2014:780752.
                    doi: 10.1155/2014/780752pubmed: 25136620google scholar: lookup
                  15. Ng TF, Vega E, Kondov NO, Markey C, Deng X, Gregoricus N, Vinjé J, Delwart E. Divergent picobirnaviruses in human feces. Genome Announc 2014 May 15;2(3).
                    doi: 10.1128/genomeA.00415-14pubmed: 24831146google scholar: lookup
                  16. Ganesh B, Bányai K, Kanungo S, Sur D, Malik YS, Kobayashi N. Detection and molecular characterization of porcine picobirnavirus in feces of domestic pigs from kolkata, India. Indian J Virol 2012 Dec;23(3):387-91.
                    doi: 10.1007/s13337-012-0106-zpubmed: 24293831google scholar: lookup
                  17. Bailey KE, Gilkerson JR, Browning GF. Equine rotaviruses--current understanding and continuing challenges. Vet Microbiol 2013 Nov 29;167(1-2):135-44.
                    doi: 10.1016/j.vetmic.2013.07.010pubmed: 23932076google scholar: lookup
                  18. Harris R, Sankar K, Small JA, Suepaul R, Stewart-Johnson A, Adesiyun A. Prevalence and characteristics of enteric pathogens detected in diarrhoeic and non-diarrhoeic foals in trinidad. Vet Med Int 2012;2012:724959.
                    doi: 10.1155/2012/724959pubmed: 22792513google scholar: lookup
                  19. Wang Y, Bányai K, Tu X, Jiang B. Simian genogroup I picobirnaviruses: prevalence, genetic diversity, and zoonotic potential. J Clin Microbiol 2012 Aug;50(8):2779-82.
                    doi: 10.1128/JCM.00634-12pubmed: 22622441google scholar: lookup
                  20. Woo PC, Lau SK, Bai R, Teng JL, Lee P, Martelli P, Hui SW, Yuen KY. Complete genome sequence of a novel picobirnavirus, otarine picobirnavirus, discovered in California sea lions. J Virol 2012 Jun;86(11):6377-8.
                    doi: 10.1128/JVI.00686-12pubmed: 22570247google scholar: lookup
                  21. Zintl A, Mulcahy G, de Waal T, de Waele V, Byrne C, Clyne M, Holden N, Fanning S. An Irish perspective on Cryptosporidium. Part 2. Ir Vet J 2006 Sep 1;59(9):495-500.
                    doi: 10.1186/2046-0481-59-9-495pubmed: 21851686google scholar: lookup
                  22. Ganesh B, Nagashima S, Ghosh S, Nataraju SM, Rajendran K, Manna B, Ramamurthy T, Niyogi SK, Kanungo S, Sur D, Kobayashi N, Krishnan T. Detection and molecular characterization of multiple strains of Picobirnavirus causing mixed infection in a diarrhoeic child: Emergence of prototype Genogroup II-like strain in Kolkata, India. Int J Mol Epidemiol Genet 2011 Jan 1;2(1):61-72.
                    pubmed: 21537403
                  23. Ganesh B, Banyai K, Masachessi G, Mladenova Z, Nagashima S, Ghosh S, Nataraju SM, Pativada M, Kumar R, Kobayashi N. Genogroup I picobirnavirus in diarrhoeic foals: can the horse serve as a natural reservoir for human infection?. Vet Res 2011 Mar 17;42(1):52.
                    doi: 10.1186/1297-9716-42-52pubmed: 21414192google scholar: lookup
                  24. Frederick J, Giguère S, Sanchez LC. Infectious agents detected in the feces of diarrheic foals: a retrospective study of 233 cases (2003-2008). J Vet Intern Med 2009 Nov-Dec;23(6):1254-60.
                    doi: 10.1111/j.1939-1676.2009.0383.xpubmed: 19747192google scholar: lookup
                  25. Ceylan E, Berktas M, Ağaoğlu Z. The occurrence and antibiotic resistance of motile Aeromonas in livestock. Trop Anim Health Prod 2009 Feb;41(2):199-204.
                    doi: 10.1007/s11250-008-9175-9pubmed: 18481193google scholar: lookup
                  26. Magdesian KG. Neonatal foal diarrhea. Vet Clin North Am Equine Pract 2005 Aug;21(2):295-312, vi.
                    doi: 10.1016/j.cveq.2005.04.009pubmed: 16051051google scholar: lookup
                  27. Wales AD, Woodward MJ, Pearson GR. Attaching-effacing bacteria in animals. J Comp Pathol 2005 Jan;132(1):1-26.
                    doi: 10.1016/j.jcpa.2004.09.005pubmed: 15629476google scholar: lookup
                  28. Hathcock TL, Schumacher J, Wright JC, Stringfellow J. The prevalence of Aeromonas species in feces of horses with diarrhea. J Vet Intern Med 1999 Jul-Aug;13(4):357-60.
                    doi: 10.1892/0891-6640(1999)013<0357:tposif>2.3.co;2pubmed: 10449228google scholar: lookup
                  29. Isa P, Wood AR, Netherwood T, Ciarlet M, Imagawa H, Snodgrass DR. Survey of equine rotaviruses shows conservation of one P genotype in background of two G genotypes. Arch Virol 1996;141(9):1601-12.
                    doi: 10.1007/BF01718285pubmed: 8893784google scholar: lookup
                  30. Netherwood T, Wood JL, Townsend HG, Mumford JA, Chanter N. Foal diarrhoea between 1991 and 1994 in the United Kingdom associated with Clostridium perfringens, rotavirus, Strongyloides westeri and Cryptosporidium spp. Epidemiol Infect 1996 Oct;117(2):375-83.
                    doi: 10.1017/s0950268800001564pubmed: 8870636google scholar: lookup
                  31. Browning GF, Begg AP. Prevalence of G and P serotypes among equine rotaviruses in the faeces of diarrhoeic foals. Arch Virol 1996;141(6):1077-89.
                    doi: 10.1007/BF01718611pubmed: 8712925google scholar: lookup
                  32. Imagawa H, Tanaka T, Sekiguchi K, Fukunaga Y, Anzai T, Minamoto N, Kamada M. Electropherotypes, serotypes, and subgroups of equine rotaviruses isolated in Japan. Arch Virol 1993;131(1-2):169-76.
                    doi: 10.1007/BF01379088pubmed: 8392320google scholar: lookup
                  33. Dwyer RM. Rotaviral diarrhea. Vet Clin North Am Equine Pract 1993 Aug;9(2):311-9.
                    doi: 10.1016/s0749-0739(17)30398-xpubmed: 8358646google scholar: lookup
                  34. Imagawa H, Ishida S, Uesugi S, Masanobu K, Fukunaga Y, Nakagomi O. Genetic analysis of equine rotavirus by RNA-RNA hybridization. J Clin Microbiol 1994 Aug;32(8):2009-12.
                    doi: 10.1128/jcm.32.8.2009-2012.1994pubmed: 7989559google scholar: lookup
                  35. Dwyer RM. Progress in identifying the aetiologies of infectious foal diarrhoea. Equine Vet J 1991 Nov;23(6):397-8.
                    doi: 10.1111/j.2042-3306.1991.tb03747.xpubmed: 1778153google scholar: lookup
                  36. Browning GF, Chalmers RM, Fitzgerald TA, Snodgrass DR. Evidence for two serotype G3 subtypes among equine rotaviruses. J Clin Microbiol 1992 Feb;30(2):485-91.
                    doi: 10.1128/jcm.30.2.485-491.1992pubmed: 1371520google scholar: lookup
                  37. Borba KER, Legere RM, Canaday NM, Skrobarczyk JW, Arnold ZWT, Cotton-Betteridge E, Poveda C, Criscitiello MF, Bordin AI, Berghman LR, Pollet JBK, Cohen ND. Maternal Immunization with VP8* mRNA Vaccine Yields Superior Passive Transfer of Rotavirus-Neutralizing Antibodies to Foals. Vaccines (Basel) 2026 Jan 9;14(1).
                    doi: 10.3390/vaccines14010076pubmed: 41600992google scholar: lookup
                  38. Cullinane A, Garvey M, Dayot L, Lukaseviciute G. Equine Rotavirus A Outbreaks in Ireland (2023-2024): An Epidemiological Investigation and Virus Genotyping. Viruses 2025 Mar 31;17(4).
                    doi: 10.3390/v17040511pubmed: 40284954google scholar: lookup
                  39. Kabir A, Lamichhane B, Habib T, Adams A, El-Sheikh Ali H, Slovis NM, Troedsson MHT, Helmy YA. Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond-A Comprehensive Review. Antibiotics (Basel) 2024 Jul 29;13(8).
                    doi: 10.3390/antibiotics13080713pubmed: 39200013google scholar: lookup
                  40. Carossino M, Vissani MA, Barrandeguy ME, Balasuriya UBR, Parreño V. Equine Rotavirus A under the One Health Lens: Potential Impacts on Public Health. Viruses 2024 Jan 16;16(1).
                    doi: 10.3390/v16010130pubmed: 38257830google scholar: lookup
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