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Home / Equine Research Bank / Pol J Vet Sci / Therapeutic effect of adipose-derived mesenchymal stem cell ...
Polish journal of veterinary sciences2013; 16(4); 753-754; doi: 10.2478/pjvs-2013-0107

Therapeutic effect of adipose-derived mesenchymal stem cell injection in horses suffering from bone spavin.

Abstract: In this article we demonstrate the efficiency of autologous transplantations of adipose-derived mesenchymal stem cells for equine bone spavin treatment. Horses qualified to the study were divided into three groups: (i) research - treated with intra-articular injections of autologous stem cells, (ii) comparison treated with steroid drugs and (iii) control - untreated. All animals underwent comprehensive clinical examination before and after treatment. Our research confirms the long-term beneficial influence resulting from stem cell therapy in horse bone spavin treatment, in contrast to routine steroid usage.
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Publication Date: 2013-01-01 PubMed ID: 24597313DOI: 10.2478/pjvs-2013-0107Google Scholar: Lookup
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  • Controlled Clinical Trial
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research paper explores the beneficial effects of adipose-derived mesenchymal stem cell injections as a promising treatment for horses affected by bone spavin, when compared to routine steroid usage or no treatment.

Introduction

  • The paper begins by outlining the importance of finding effective treatment methods for bone spavin, a common equine health issue. This research was driven by the need to provide better and more reliable therapies for horses suffering from this condition, thus enhancing their quality of life and productivity.
  • While steroids are commonly used for treatment, their long-term efficacy is uncertain, thereby necessitating exploration into alternative treatment remedies such as stem cell therapy.

Methodology

  • The selected horses for the study were divided into three distinct groups for comparative purposes. The first group is the research group, which was treated with intra-articular injections of autologous stem cells. The second group, the comparison group, was traditionally treated with steroid drugs. The last group acted as the control group, receiving no treatment.
  • Comprehensive clinical examinations were performed on all horses before and after treatments to assess the effectiveness of the applied therapeutic methods.

Results

  • The research findings indicated a notable positive impact resulting from stem cell therapy in the treatment of bone spavin in horses.
  • Horses treated with adipose-derived mesenchymal stem cell injections demonstrated significant improvements when compared to those treated with steroids or untreated horses, validating the efficacy of stem cell therapy in this context.

Conclusion

  • The researchers concluded that autologous transplantations of adipose-derived mesenchymal stem cells could be an effective long-term treatment alternative for equine bone spavin. This contrasted with the routine usage of steroids, which did not demonstrate a comparable long-term beneficial effect.
  • This study thus provides valuable insights into the potential benefits of stem cell therapies in veterinary medicine, offering a possible new direction for improving the treatment of bone spavin in horses.

Cite This Article

APA
Nicpoń J, Marycz K, Grzesiak J. (2013). Therapeutic effect of adipose-derived mesenchymal stem cell injection in horses suffering from bone spavin. Pol J Vet Sci, 16(4), 753-754. https://doi.org/10.2478/pjvs-2013-0107

Publication

Polish journal of veterinary sciences
ISSN: 1505-1773
NlmUniqueID: 101125473
Country: Germany
Language: English
Volume: 16
Issue: 4
Pages: 753-754

Researcher Affiliations

Nicpoń, J
  • Department of Surgery, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, pl. Grunwaldzki 51, 50-366 Wroclaw, Poland. nickub@poczta.onet.pl
Marycz, K
  • Electron Microscopy Laboratory, University of Environmental and Life Sciences, Kozuchowska 5b, 50-375 Wroclaw, Poland.
Grzesiak, J
  • Electron Microscopy Laboratory, University of Environmental and Life Sciences, Kozuchowska 5b, 50-375 Wroclaw, Poland.

MeSH Terms

  • Adipose Tissue / cytology
  • Animals
  • Betamethasone / administration & dosage
  • Betamethasone / therapeutic use
  • Horse Diseases / therapy
  • Horses
  • Inflammation / therapy
  • Inflammation / veterinary
  • Joint Diseases / veterinary
  • Lameness, Animal
  • Mesenchymal Stem Cells / physiology

Citations

This article has been cited 27 times.
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