Therapy of equine infectious keratitis: a review.
- Journal Article
- Review
Summary
This research article is focused on understanding the pathogenesis, management, and treatment methods of infectious keratitis in horses and devising a therapeutic protocol for this condition.
Understanding Infectious Keratitis in Horses
Infectious keratitis is a serious eye disease in horses caused by a variety of pathogens. It can result in severe complications such as vision loss if not properly and promptly treated. This research article starts by explaining the pathogenesis (origin and development) of this disease. The researchers delve into:
- The physiological and metabolic processes that can lead to this disease in horses.
- The common causes including bacterial, viral, or fungal infections.
- The impact of environment and genetics on the risk of developing the disease.
Management of Infectious Keratitis in Horses
After understanding how the disease originates and develops, the researchers further discuss the management aspects. Here they detail:
- Appropriate horse care and hygiene practices to prevent the onset of infectious keratitis.
- The importance of regular medical check-ups, especially eye examinations for horses, to detect early signs of the disease and initiate timely treatment.
- The role of isolation, rest, and supportive care for affected horses to prevent further spread and complications.
Pharmacological Aspects
The pharmacological aspects section covers the medicinal part of the disease treatment. It explains:
- The types of drugs used for therapeutic purposes, and how they work to treat infectious keratitis in horses.
- The side effects associated with these drugs, and how they can be effectively managed or mitigated.
- The recommended dosage and frequency of medication for different horses based on their breed, age, severity of disease, and general health condition.
Devising a Therapeutic Protocol
Finally, this paper also provides a comprehensive guideline to devise an effective therapeutic protocol for treating horses suffering from infectious keratitis. The protocol includes:
- Local and systemic drug administration strategies.
- Frequency of treatment and follow-ups.
- Monitoring and adjusting treatment strategies based on the horse’s response to therapy and recovery progress.
- Long-term care plan to prevent recurrence and secondary complications.
Cite This Article
Publication
Researcher Affiliations
- North Carolina State University, Department of Clinical Sciences, College of Veterinary Medicine, Raleigh, North Carolina, USA.
MeSH Terms
- Animals
- Anti-Bacterial Agents / therapeutic use
- Antifungal Agents / therapeutic use
- Horse Diseases / drug therapy
- Horses
- Keratitis / drug therapy
- Keratitis / microbiology
- Keratitis / veterinary
Citations
This article has been cited 5 times.- Galera PD, Brooks DE. Optimal management of equine keratomycosis. Vet Med (Auckl) 2012;3:7-17.
- Czerwinski SL, Lyon AW, Skorobohach B, Léguillette R. Pharmacokinetic analysis of topical tobramycin in equine tears by automated immunoassay. BMC Vet Res 2012 Aug 21;8:141.
- Stolle LM, Oltmanns H, Meißner J, Heun F, Schieder AK, Wolff HT, Ohnesorge B, Busse C. Polyhexanide, Povidone-Iodine, and Hypochlorous Acid Show High In Vitro Antimicrobial Efficacy Against Pathogens Commonly Associated With Equine Infectious Keratitis. Vet Ophthalmol 2026 Jan;29(1):e70141.
- Kubai MA, Roy MM, Stinman CC, Kenne DE, Allbaugh RA, Sebbag L. Topical blood products modulate the effects of ophthalmic antibiotics against common bacterial pathogens in dogs with infectious keratitis. Front Vet Sci 2024;11:1417842.
- Roberts D, Salmon J, Cubeta MA, Gilger BC. Phase-Dependent Differential In Vitro and Ex Vivo Susceptibility of Aspergillus flavus and Fusarium keratoplasticum to Azole Antifungals. J Fungi (Basel) 2023 Sep 26;9(10).