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Equine veterinary journal. Supplement2010; (37); 19-23; doi: 10.1111/j.2042-3306.2010.tb05630.x

Therapy of equine infectious keratitis: a review.

Abstract: The following article briefly discusses the pathogenesis of infectious keratitis in the horse, followed by discussion of management and pharmacological aspects to be considered when devising a therapeutic protocol for affected patients.
Publication Date: 2010-10-14 PubMed ID: 20939162DOI: 10.1111/j.2042-3306.2010.tb05630.xGoogle Scholar: Lookup
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  • Journal Article
  • Review

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article is focused on understanding the pathogenesis, management, and treatment methods of infectious keratitis in horses and devising a therapeutic protocol for this condition.

Understanding Infectious Keratitis in Horses

Infectious keratitis is a serious eye disease in horses caused by a variety of pathogens. It can result in severe complications such as vision loss if not properly and promptly treated. This research article starts by explaining the pathogenesis (origin and development) of this disease. The researchers delve into:

  • The physiological and metabolic processes that can lead to this disease in horses.
  • The common causes including bacterial, viral, or fungal infections.
  • The impact of environment and genetics on the risk of developing the disease.

Management of Infectious Keratitis in Horses

After understanding how the disease originates and develops, the researchers further discuss the management aspects. Here they detail:

  • Appropriate horse care and hygiene practices to prevent the onset of infectious keratitis.
  • The importance of regular medical check-ups, especially eye examinations for horses, to detect early signs of the disease and initiate timely treatment.
  • The role of isolation, rest, and supportive care for affected horses to prevent further spread and complications.

Pharmacological Aspects

The pharmacological aspects section covers the medicinal part of the disease treatment. It explains:

  • The types of drugs used for therapeutic purposes, and how they work to treat infectious keratitis in horses.
  • The side effects associated with these drugs, and how they can be effectively managed or mitigated.
  • The recommended dosage and frequency of medication for different horses based on their breed, age, severity of disease, and general health condition.

Devising a Therapeutic Protocol

Finally, this paper also provides a comprehensive guideline to devise an effective therapeutic protocol for treating horses suffering from infectious keratitis. The protocol includes:

  • Local and systemic drug administration strategies.
  • Frequency of treatment and follow-ups.
  • Monitoring and adjusting treatment strategies based on the horse’s response to therapy and recovery progress.
  • Long-term care plan to prevent recurrence and secondary complications.

Cite This Article

APA
Clode AB. (2010). Therapy of equine infectious keratitis: a review. Equine Vet J Suppl(37), 19-23. https://doi.org/10.1111/j.2042-3306.2010.tb05630.x

Publication

NlmUniqueID: 9614088
Country: United States
Language: English
Issue: 37
Pages: 19-23

Researcher Affiliations

Clode, A B
  • North Carolina State University, Department of Clinical Sciences, College of Veterinary Medicine, Raleigh, North Carolina, USA.

MeSH Terms

  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / therapeutic use
  • Horse Diseases / drug therapy
  • Horses
  • Keratitis / drug therapy
  • Keratitis / microbiology
  • Keratitis / veterinary

Citations

This article has been cited 5 times.
  1. Galera PD, Brooks DE. Optimal management of equine keratomycosis. Vet Med (Auckl) 2012;3:7-17.
    doi: 10.2147/VMRR.S25013pubmed: 30155429google scholar: lookup
  2. Czerwinski SL, Lyon AW, Skorobohach B, Léguillette R. Pharmacokinetic analysis of topical tobramycin in equine tears by automated immunoassay. BMC Vet Res 2012 Aug 21;8:141.
    doi: 10.1186/1746-6148-8-141pubmed: 22909398google scholar: lookup
  3. Stolle LM, Oltmanns H, Meißner J, Heun F, Schieder AK, Wolff HT, Ohnesorge B, Busse C. Polyhexanide, Povidone-Iodine, and Hypochlorous Acid Show High In Vitro Antimicrobial Efficacy Against Pathogens Commonly Associated With Equine Infectious Keratitis. Vet Ophthalmol 2026 Jan;29(1):e70141.
    doi: 10.1111/vop.70141pubmed: 41552904google scholar: lookup
  4. Kubai MA, Roy MM, Stinman CC, Kenne DE, Allbaugh RA, Sebbag L. Topical blood products modulate the effects of ophthalmic antibiotics against common bacterial pathogens in dogs with infectious keratitis. Front Vet Sci 2024;11:1417842.
    doi: 10.3389/fvets.2024.1417842pubmed: 39071784google scholar: lookup
  5. Roberts D, Salmon J, Cubeta MA, Gilger BC. Phase-Dependent Differential In Vitro and Ex Vivo Susceptibility of Aspergillus flavus and Fusarium keratoplasticum to Azole Antifungals. J Fungi (Basel) 2023 Sep 26;9(10).
    doi: 10.3390/jof9100966pubmed: 37888221google scholar: lookup