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Therapy resistant septic enteritis due to a jejunal malformation in a 5-day-old Thoroughbred colt.

Abstract: A 5-day-old Thoroughbred colt was presented with profuse watery diarrhea, hypovolemic shock, and a patent urachus. Despite intensive medical therapy, the colt was euthanized 15 d later due to poor clinical response. Necropsy revealed a small intestinal structural abnormality that formed a closed jejunal ring. Although rare, intestinal malformations should be considered in neonatal foals with clinical signs resembling enteritis. Entérite septique résistante au traitement causée par une malformation jéjunale chez un poulain Thoroughbred âgé de 5 jours. Un poulain Thoroughbred âgé de 5 jours a été présenté avec une diarrhée aqueuse abondante, un choc hypovolémique et un ouraque évident. Malgré une thérapie médicale intensive, le poulain a été euthanasié 15 jours plus tard en raison d’une mauvaise réponse clinique. La nécropsie a révélé une petite anomalie intestinale structurelle qui a formé un anneau jéjunal fermé. Quoique rares, les malformations intestinales devraient être considérées chez les poulains nouveau-nés qui présentent des signes cliniques s’apparentant à l’entérite. (Traduit par Isabelle Vallières)
Publication Date: 2011-05-03 PubMed ID: 21532818PubMed Central: PMC3022449
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Summary

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The research paper discusses a case of a 5-day-old Thoroughbred colt, whose severe medical conditions could not be treated effectively due to a rare intestinal malformation, leading to its euthanasia 15 days post its presentation.

Background and Case

  • The case study focuses on a very young Thoroughbred colt, presented with severe and worrying symptoms like abundant watery diarrhea (enteritis), a condition of shock induced by a decrease in the blood volume (hypovolemic shock), and a patent urachus, an abnormality where the passageway between the umbilical cord and the bladder doesn’t close after birth.
  • Despite the application of intensive medical therapy designed to help the young colt recover, the symptoms continued to persist in a severe manner.
  • Due to the animal’s poor response to therapy and deteriorating condition, the decision was taken to euthanize the colt after 15 days of treatment.

Necropsy Findings

  • A necropsy, a post-mortem examination, was performed on the colt after its euthanasia.
  • The examination revealed a rare form of small intestinal structural abnormality in the colt. This abnormality had led to the formation of a closed jejunal ring. The jejunum is a part of the small intestine that absorbs nutrients from digested food, and a closed ring formation would severely affect this process. This was determined to be the main cause behind the persistent and extreme symptoms that the colt was experiencing.

Takeaway

  • Though they are rare, the study suggests that intestinal malformations be considered when newborn foals exhibit clinical signs similar to those of enteritis.
  • The study underscores the importance of recognising these rare conditions early on, as they can severely affect a foal’s ability to respond to medical treatment and ultimately, its chances of survival.

Cite This Article

APA
Staempfli SA, Saied A, Wakamatsu N, Serra V, Eades SC. (2011). Therapy resistant septic enteritis due to a jejunal malformation in a 5-day-old Thoroughbred colt. Can Vet J, 52(2), 142-146.

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 52
Issue: 2
Pages: 142-146

Researcher Affiliations

Staempfli, Simon A
  • Departments of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Louisiana, USA. simon.staempfli@arundelhorsevets.co.uk
Saied, Ahmad
    Wakamatsu, Nobuko
      Serra, Verna
        Eades, Susan C

          MeSH Terms

          • Animals
          • Animals, Newborn
          • Diagnosis, Differential
          • Enteritis / diagnosis
          • Enteritis / etiology
          • Enteritis / therapy
          • Enteritis / veterinary
          • Euthanasia, Animal
          • Horse Diseases / diagnosis
          • Horse Diseases / etiology
          • Horses
          • Jejunum / abnormalities
          • Male
          • Sepsis / diagnosis
          • Sepsis / etiology
          • Sepsis / therapy
          • Sepsis / veterinary

          References

          This article includes 29 references
          1. Cohen ND. Causes of and farm management factors associated with disease and death in foals.. J Am Vet Med Assoc 1994;204:1644–1651.
            pubmed: 8050947
          2. Magdesian KG. Neonatal foal diarrhea.. Vet Clin North Am Equine Pract 2005;21:295–312.
            pmc: PMC7135406pubmed: 16051051
          3. Yovich JV, Horney FD. Congenital jejunal diverticulum in a foal.. J Am Vet Med Assoc 1983;183:1092.
            pubmed: 6417087
          4. Grant BD, Tennant B. Volvulus associated with Meckel’s diverticulum in the horse.. J Am Vet Med Assoc 1973;162:550–551.
            pubmed: 4692819
          5. Madison JB, Dreyfuss DJ, Charlton C. Ileal diverticulum as a cause of chronic colic in a horse.. J Am Vet Med Assoc 1991;198:453–454.
            pubmed: 1901307
          6. Cook G, Blikslager AT, Bristol DG. Colic associated with a jejunal diverticulum in a mature horse.. Equine Vet Educ 1996;8:143–144.
          7. Riccaboni P, Tassan S, Mayer P. Rare intestinal malformation (diverticulum confluens) in a horse.. Equine Vet J 2000;32:351–353.
            pubmed: 10952386
          8. Barakzai SZ, Swain JM, Else RW, Licka T, Dixon PM. Two cases of small intestinal strangulation involving Meckel’s diverticulae.. Equine Vet Educ 2003;15:291–294.
          9. Reef VB, Collatos C. Ultrasonography of umbilical structures in clinically normal foals.. Am J Vet Res 1988;49:2143–2146.
            pubmed: 3071195
          10. Brewer BD, Koterba AM. Development of a scoring system for the early diagnosis of equine neonatal sepsis.. Equine Vet J 1988;20:18–22.
            pubmed: 3366100
          11. Godlueck G. Missbildungen des Darmes.. In: Joest E, editor. Handbuch der speziellen pathologischen Anatomie der Haustiere; Band VI — Digestinonsapparat. 3rd ed. Berlin u. Hamburg: Parey Verlag; 1967. pp. 354–367.
          12. Schmidt J. Missbildungen am Darm des Pferdes.. Berlin Muenchen Tieraerztl Wschr 1940;43:406–409.
          13. Bassage LH, Habecker PL, Russell EA, Ennulat D. Colic in a horse associated with a massive cystic duplication of the ascending colon.. Equine Vet J 2000;32:565–568.
            pubmed: 11093634
          14. Mair TS. Colic associated with a malformation of the ascending colon in a horse.. Vet Rec 2002;151:152–153.
            pubmed: 12199437
          15. Robert MP, Benamou-Smith AE, Cadore JL, Rosengarten MS, Lepage OM. Recurrent colics in a 9-year-old Arabian stallion due to several congenital anomalies.. Equine Vet Educ 2008;20:567–571.
          16. Joest E. Doppeldivertikel am kleinen Colon eines Pferdes. Tieraerztliche Hochschule Dresden — Jahresbericht Vet Med 1910;31:145.
          17. Kitt T. Lehrbuch der pathologischen Anatomie der Haustiere.. 5th ed. Enke Verlag; Stuttgart: 1923. Anomalien des Darmes; pp. 302–489.
          18. Bremer JL. Diverticula and duplications of the intestinal tract.. Arch Pathol 1944;38:132–140.
          19. Lewis FT, Thying FW. Regular occurrence of intestinal diverticula in embryos of pig, rabbit, and man.. Am J Anat 1908;7:505–519.
          20. Southwood LL. Gastrointestinal tract diverticula: What, when and why?. Equine Vet Educ 2008;20:572–574.
          21. Hahn C. Magenaehnliches Divertikel des Hueftdarmes bei Pferden.. Arch Tierheilkunde 1877;3:45–50.
          22. Beckman KE, Del Piero F, Donaldson MT, Seco O, Reef V. Imaging diagnosis — Intramural hematoma, jejunal diverticulum and colic in a horse.. Vet Radio Ultrasound 2008;49:81–84.
            pubmed: 18251300
          23. Freeman DE. Small intestine.. In: Auer JA, Stick JA, editors. Equine Surgery. 3rd ed. Philadelphia: WB Saunders; 2006. pp. 401–436.
          24. Kielar A. Imaging of the small bowel: Challenges and advances in imaging techniques.. J Med Imag Rad Sci 2008;39:55–63.
            pubmed: 31051803
          25. Schleef J, Schalamon J. The role of laparoscopy in the diagnosis and treatment of intestinal duplication in childhood. A report of two cases.. Surgical endoscopy 2000;14:865.
            pubmed: 11287999
          26. Holcomb GW, Gheissari A, O’Neill J, Shorter NA, Bishop HC. Surgical management of alimentary tract duplications.. Ann Surgery 1989;209:167–174.
            pmc: PMC1493914pubmed: 2916861
          27. Marsh PS, Palmer JE. Bacterial isolates from blood and their susceptibility patterns in critically ill foals: 543 cases (1991–1998). J Am Vet Med Assoc 2001;218:1608–1610.
            pubmed: 11393374
          28. Flournoy DJ, Reinert RL, Bell-Dixon C, Gentry CA. Increasing antimicrobial resistance in gram-negative bacilli isolated from patients in intensive care units.. Am J Infect Control 2000;28:244–250.
            pubmed: 10840345
          29. Bassetti M, Cruciani M, Righi E. Antimicrobial use and resistance among gram-negative bacilli in an Italian intensive care unit (ICU). J Chemother 2006;18:261–267.
            pubmed: 17129836

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