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The Veterinary clinics of North America. Equine practice2018; 34(3); 485-498; doi: 10.1016/j.cveq.2018.07.006

Topical Wound Medications.

Abstract: Topical therapies are used in equine wound healing to clean and decontaminate the wound environment after acute injury and to promote healing and decrease the risk of infection once the wound has initially been treated. Evolving antibiotic resistance has prompted judicious use of systemic antimicrobials, particularly in the treatment of local infections, such as wounds. The use of topical antiseptics to disinfect acute wounds and topical antimicrobials to manage chronic wounds is necessary to achieve successful healing. In addition, many topical medications can alter the wound environment to promote rapid and effective wound healing.
Publication Date: 2018-11-19 PubMed ID: 30447767DOI: 10.1016/j.cveq.2018.07.006Google Scholar: Lookup
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Summary

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This research investigates the use and effectiveness of topical medications in treating wounds in horses, in response to increasing antibiotic resistance and the need for careful use of systemic antimicrobials.

Overview of the Research

The purpose of this research was to explore ways of treating wounds in horses, particularly focusing on the use of topical therapies. This was motivated by the increasing resistance to antibiotics. The resistance is prompting a more careful use of systemic antimicrobials, particularly when dealing with local infections like wounds.

  • The researchers looked into how these topical medications help both in cleaning and decontaminating the wound environment after an acute injury, as well as in promoting wound healing and reducing risk of infection after initial treatment of the wound.
  • They emphasized the necessity of using topical antiseptics to disinfect new wounds and topical antimicrobials to manage old wounds, for successful wound healing to be achieved.

Findings of the Research

The research emphasizes that topical medications play a significant role in wound management in equine.

  • Topical therapies aid in sterilizing and purging the wound environment following acute injury.
  • Topical medications also contribute to promoting the healing process and reducing the chances of infection after the wound has initially been treated.
  • The use of topical antiseptics is critical in the disinfection of acute wounds, while the use of topical antimicrobials is key in managing chronic wounds.
  • It was noted that not only do these topical medications manage wound infection, but they also alter the wound environment in a way that promotes rapid and effective wound healing.

Implications of the Research

The findings of the research suggest potential improvements in equine wound care procedures.

  • The research underscores the need for a planned and judicious use of systemic antimicrobials, particularly in wound treatment, considering the growing issue of antibiotic resistance.
  • The findings advocate for a greater use of topical antiseptics and antimicrobials in the management of both acute and chronic wounds in horses.
  • The study might be useful in the development of better wound treatment strategies for other animals and potentially humans as well, due to shared concerns over antibiotic resistance.

Cite This Article

APA
Leise BS. (2018). Topical Wound Medications. Vet Clin North Am Equine Pract, 34(3), 485-498. https://doi.org/10.1016/j.cveq.2018.07.006

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 34
Issue: 3
Pages: 485-498

Researcher Affiliations

Leise, Britta S
  • Equine Surgery, Veterinary Clinical Sciences, Louisiana State University, School of Veterinary Medicine, Skip Bertman Drive, Baton Rouge, LA 70803, USA. Electronic address: bleise@lsu.edu.

MeSH Terms

  • Administration, Topical
  • Animals
  • Anti-Infective Agents, Local / administration & dosage
  • Anti-Infective Agents, Local / adverse effects
  • Extremities / injuries
  • Horse Diseases / drug therapy
  • Horses
  • Wound Healing / drug effects
  • Wounds and Injuries / drug therapy
  • Wounds and Injuries / veterinary

Citations

This article has been cited 5 times.
  1. Pimenta J, Dias C, Cotovio M, Saavedra MJ. In Vitro Effect of Eucalyptus Essential Oils and Antiseptics (Chlorhexidine Gluconate and Povidone-Iodine) against Bacterial Isolates from Equine Wounds. Vet Sci 2023 Dec 26;11(1).
    doi: 10.3390/vetsci11010012pubmed: 38250918google scholar: lookup
  2. Mircea S, Laura M, Sebastian HM, Lucian BI, Maria FD, Daniel C, Dragos CC, Loredana HL, Liliana S, Bianca MP. Assessing the Efficacy of Laser Therapy and Autologous Platelet-Rich Plasma (PRP) Treatment for Chronic Wounds. J Pers Med 2024 Jan 11;14(1).
    doi: 10.3390/jpm14010085pubmed: 38248786google scholar: lookup
  3. Horgos MS, Pop OL, Sandor M, Borza IL, Negrean R, Marc F, Major K, Sachelarie L, Grierosu C, Huniadi A. Laser in the Treatment of Atonic Wounds. Biomedicines 2023 Jun 24;11(7).
    doi: 10.3390/biomedicines11071815pubmed: 37509454google scholar: lookup
  4. Wang Z, Xie X, Wang M, Ding M, Gu S, Xing X, Sun X. Analysis of common and characteristic actions of Panax ginseng and Panax notoginseng in wound healing based on network pharmacology and meta-analysis. J Ginseng Res 2023 Jul;47(4):493-505.
    doi: 10.1016/j.jgr.2023.02.005pubmed: 37397412google scholar: lookup
  5. Horgos MS, Pop OL, Sandor M, Borza IL, Negrean RA, Cote A, Neamtu AA, Grierosu C, Sachelarie L, Huniadi A. Platelets Rich Plasma (PRP) Procedure in the Healing of Atonic Wounds. J Clin Med 2023 Jun 7;12(12).
    doi: 10.3390/jcm12123890pubmed: 37373585google scholar: lookup