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The Veterinary clinics of North America. Equine practice2022; 38(2); 363-377; doi: 10.1016/j.cveq.2022.04.005

Traumatic Nervous System Injury.

Abstract: Mechanisms of traumatic nervous system injury to a degree are similar, but differences exist in etiology, pathophysiology, and treatment of brain, spinal cord, and peripheral nerve injury. The most common clinical abnormalities seen in the horse are abnormal level of consciousness, abnormal behavior, seizures, cranial nerve deficits, vestibular disease, tetra- and paraparesis or paraplegia, cauda equina syndrome, specific gait deficits, and muscle atrophy. Treatments are directed toward reducing inflammation and swelling, halting secondary injury, and promoting mechanisms of neuroregeneration and plasticity. Prognosis depends on the severity of primary injury and the neuroanatomic location and extent of nervous tissue damage.
Publication Date: 2022-07-07 PubMed ID: 35810150DOI: 10.1016/j.cveq.2022.04.005Google Scholar: Lookup
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Summary

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This research paper focuses on the diverse nature of traumatic injuries to the nervous system and the consequent clinical abnormalities observed in horses. The study explores common treatments such as reduction of inflammation and swelling, prevention of secondary injury, and promotion of neuroregeneration. The prognosis of such conditions, proximately determined by the severity and location of the injury, is also assessed.

Mechanisms of Traumatic Nervous System Injury

The paper first discusses the mechanisms that cause traumatic injuries to the nervous system. While some mechanisms are universally applied, including injuries to the brain, spinal cord, and peripheral nerves, it additionally outlines the unique characteristics and the different etiology, pathophysiology, and treatment methods for each type of injury.

Clinical Symptoms

Common clinical symptoms observed in horses with a traumatic nervous systems injury include:

  • Altered levels of consciousness
  • Abnormal behaviour
  • Seizures
  • Cranial nerve deficits
  • Vestibular disease
  • Paraparesis or paraplegia
  • Cauda equina syndrome
  • Specific gait deficits
  • Muscle atrophy

Treatments

The paper then talks about the strategies that are generally employed for treatments which are:

  • Directing efforts to reduce inflammation and swelling that result from the injury
  • Preventing secondary injuries which could follow the primary injury
  • Inciting processes of neuroregeneration and plasticity in an attempt to restore the damaged nervous tissue

Prognosis

Just like the treatments, the prognosis is also differential and depends on various aspects of the injury. This includes the severity of the primary injury, the anatomic location of the injury, and the extent of the nervous tissue damage. The paper infers that more severe primary injuries, larger extents of nervous tissue damage and crucial neuroanatomic location of the injury can lead to poorer prognosis.

Cite This Article

APA
Nout-Lomas YS. (2022). Traumatic Nervous System Injury. Vet Clin North Am Equine Pract, 38(2), 363-377. https://doi.org/10.1016/j.cveq.2022.04.005

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 38
Issue: 2
Pages: 363-377

Researcher Affiliations

Nout-Lomas, Yvette S
  • Department of Clinical Sciences, Johnson Family Equine Hospital, Colorado State University, 2230 Gillette Drive, Fort Collins, CO 80523-1678, USA. Electronic address: Yvette.Nout-Lomas@colostate.edu.

MeSH Terms

  • Animals
  • Horse Diseases
  • Horses
  • Spinal Cord Injuries / veterinary

Citations

This article has been cited 1 times.
  1. Yang R, Jin W, Zhang Z, Qi J, Wei Z. The application of chimeric free anterolateral thigh flap and muscle flap for heel ulcer reconstruction: A case series and technical refinements. JPRAS Open 2025 Dec;46:100-108.
    doi: 10.1016/j.jpra.2025.08.040pubmed: 41215848google scholar: lookup