Ultrastructural development of the equine placenta.
Abstract: Microcotyledons, which are a distinctive feature of the mature equine placenta, are fully formed by Day 150 of gestation. The fetal component of each microcotyledon is developed from several primary folds of trophoblast which become elaborately subdivided as gestation proceeds. These changes are reflected in the structure of the maternal crypts, which receive the fetal villi. Between Days 60 and 150 of gestation the maternal epithelium is greatly reduced in height. No such change occurs on the fetal side of the placenta, but between Days 100 and 250 a progressive indentation of the epithelium by fetal capillaries reduces the effective thickness of the placental barrier. The ultrastructural characteristics of fetal and maternal epithelia are described.
Publication Date: 1975-10-01 PubMed ID: 1060847
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- Journal Article
Summary
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The research article provides a detailed study of the development stages of the horse placenta, in particular focusing on the creation and development of microcotyledons – an important feature of a mature horse placenta.
Understanding Microcotyledons and their Development
- The research article puts emphasis on the understanding of microcotyledons and their development in an equine placenta. Microcotyledons are noteworthy features of the mature equine placenta, formed by the 150th day of gestation.
- Development of the fetal portion of these microcotyledons occur from numerous primary creases of the trophoblast (cells forming the outer layer of a blastocyst), which become increasingly complex as the gestation period advances.
Structural Changes in Maternal Crypts
- The changes in the trophoblast are reflected in the structure of the maternal crypts, which are designed to accommodate the fetal villi.
- The height of the maternal epithelium substantially reduces between the 60th and the 150th day of gestation, as per the research findings.
Transformation on the Fetal Side of the Placenta
- No alteration in height is observed on the fetal side of the placenta unlike the maternal side. However, there exists structural changes between the 100th to the 250th day of gestation where the epithelium indentation by the fetal capillaries reduces the effective thickness of the placental barrier.
Ultrastructural Characteristics Analysis
- Lastly, the research article comprehensively describes the ultrastructural characteristics (microscopic details relating to tissue and cell structure) of both the fetal and maternal epithelia, presenting an in-depth understanding of the developmental progress of the placenta.
Cite This Article
APA
Samuel CA, Allen WR, Steven DH.
(1975).
Ultrastructural development of the equine placenta.
J Reprod Fertil Suppl(23), 575-578.
Publication
Researcher Affiliations
MeSH Terms
- Animals
- Female
- Fetus / physiology
- Gestational Age
- Horses / physiology
- Placenta / ultrastructure
- Placentation
- Pregnancy
Citations
This article has been cited 4 times.- Martinez RE, Leatherwood JL, Bradbery AN, Paris BL, Hammer CJ, Kelley D, Bazer FW, Wu G. Evaluation of dietary arginine supplementation to increase placental nutrient transporters in aged mares. Transl Anim Sci 2023 Jan;7(1):txad058.
- Neto da Silva AC, Costa AL, Teixeira A, Alpoim-Moreira J, Fernandes C, Fradinho MJ, Rebordão MR, Silva E, Ferreira da Silva J, Bliebernicht M, Alexandre-Pires G, Ferreira-Dias G. Collagen and Microvascularization in Placentas From Young and Older Mares. Front Vet Sci 2021;8:772658.
- Loux SC, Dini P, El-Sheikh Ali H, Kalbfleisch T, Ball BA. Characterization of the placental transcriptome through mid to late gestation in the mare. PLoS One 2019;14(11):e0224497.
- Kimura Y, Sasaki M, Watanabe K, Dhakal P, Sato F, Taya K, Nambo Y. Expression of activin receptors in the equine uteroplacental tissue: an immunohistochemical analysis. J Equine Sci 2018;29(2):33-37.
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