Update on equine laminitis.

This research article explores the latest findings on equine laminitis, a serious health condition that affects the hooves of horses. The studies discussed have furthered understanding of the mechanisms behind the onset of laminitis, and have led to improved prevention methods and treatments.

Historical Background of Equine Laminitis

• The authors provide an historical overview of our knowledge of equine laminitis. Until recently, it was known that the long-term detrimental effects of this condition were associated with the rotation of the coffin bone, which is a hoof bone in horses. This often resulted from differing growth rates of the quarter and toe areas of the hoof, paired with the unique growth pattern of the laminitis hoof.
• The onset of laminitis was demonstrated in correlation to high-carbohydrate diets, which included lush growing grasses. Other contributing factors included ingesting excessive amounts of cold water, retention of the placenta (a condition that occurs post-foaling), and over-exertion on hard surfaces.

Recent Research on Laminitis

• This article presents recent research that has led to a better understanding of the systemic events leading to laminitis, which essentially provides the rationale behind local changes witnessed in an affected horse’s foot. Studies have explored in-depth the series of events that lead to this debilitating condition, thereby expanding our understanding of laminitis beyond the historical context.
• Nevertheless, the authors indicate that the research field remains incomplete as not all mechanisms responsible for laminitis have been identified. Despite the undeveloped areas of this research, the investigation has led to significant improvements in preventative measures and therapeutic recommendations for treating laminitis in horses.
• The authors express their intent to review these new investigative findings and discuss how they have contributed to advances in treatment and prevention of laminitis. Additionally, the article promises to cover introductory insights into the mechanistic studies related to laminitis that are under way and how they have shaped our understanding of this serious equine health concern.