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The Veterinary clinics of North America. Equine practice2008; 24(2); 387-vii; doi: 10.1016/j.cveq.2008.05.002

Urinary clinical pathologic findings and glomerular filtration rate in the horse.

Abstract: Urinary specific gravity (USG) measurements are underused by equine ambulatory veterinarians. Urinary dipstick and USG findings can assist in the diagnosis and prognosis of many disease processes in the horse. Simple methods for measurement of the glomerular filtration rate and urinary biochemical markers can improve equine urinary diagnostic abilities in critical care patients. Fractional excretion of electrolytes and minerals assists in fluid care and in management of nutrition of horses.
Publication Date: 2008-07-26 PubMed ID: 18652961DOI: 10.1016/j.cveq.2008.05.002Google Scholar: Lookup
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Summary

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The research explores the role and significance of Urinary Specific Gravity (USG) measurements in diagnosing and prognosing various diseases in horses. It demystifies the relevance of urinary dipstick, USG findings, measurement of glomerular filtration rate and urinary biochemical markers in enhancing detection abilities for urinary disorders prevalent in critical care horse patients. The study also highlights the importance of electrolytes and minerals’ fractional excretion in fluid care and horse nutrition management.

Role of Urinary Specific Gravity (USG) Measurements

  • The research underscores the underutilization of USG measurements by equine ambulatory veterinarians, indicating a potential missed opportunity in the detection and diagnosis of various urinary disorders in horses.
  • These measurements, when incorporated into disease management protocols, can assist in determining the prognosis of diseases, enabling effective planning and adaptation of treatment strategies.

Importance of Urinary Dipstick and USG Findings

  • Urinary dipstick and USG findings provide insights into the urinary disorders in horses. According to the research, these findings can be used as a diagnostic tool to assess the health status of horses, specifically targeting urinary tract functions.
  • Such findings can also be used to monitor the progress of treatment methods, helping veterinarians make informed decisions regarding possible adjustments in treatment procedures.

Measurement of Glomerular Filtration Rate (GFR)

  • The measurement of GFR in horses is another significant parameter the research highlights. It improves the diagnostic capabilities for critical care patients who can be suffering from various urinary complications.
  • Effective measurement of GFR can aid in swift disease detection, leading to early treatment initiation, increasing the survival odds for the patient.

Role of Urinary Biochemical Markers

  • The research also underscores the potential benefits of urinary biochemical markers in disease detection.
  • When used in combination with other diagnostic parameters, these markers can contribute to comprehensive health profiles that increase the accuracy and reliability of the diagnoses.

Fractional Excretion of Electrolytes and Minerals

  • The research concludes by emphasizing the importance of fractional excretion of electrolytes and minerals, which significantly assists in fluid care and nutrition management in horses.
  • Understanding these parameters can help identify any deficits or excessive amounts, consequently shaping the dietary inputs to achieve maximum health benefits.

Cite This Article

APA
Savage CJ. (2008). Urinary clinical pathologic findings and glomerular filtration rate in the horse. Vet Clin North Am Equine Pract, 24(2), 387-vii. https://doi.org/10.1016/j.cveq.2008.05.002

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 24
Issue: 2
Pages: 387-vii

Researcher Affiliations

Savage, Catherine J
  • Equine Clinical Services, Equine Centre, University of Melbourne, 250 Princes Highway, Werribee, Victoria 3030, Australia. cjsavage@unimelb.edu.au

MeSH Terms

  • Animals
  • Biomarkers / urine
  • Glomerular Filtration Rate / physiology
  • Glomerular Filtration Rate / veterinary
  • Horse Diseases / diagnosis
  • Horse Diseases / urine
  • Horses
  • Urinalysis / instrumentation
  • Urinalysis / methods
  • Urinalysis / standards
  • Urinalysis / veterinary

Citations

This article has been cited 5 times.
  1. Fadel C, Giorgi M. Synopsis of the pharmacokinetics, pharmacodynamics, applications, and safety of firocoxib in horses.. Vet Anim Sci 2023 Mar;19:100286.
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  2. Dias DCR, Ribeiro Filho JD, Viana RB, Bittencourt TCC, Dantas FTDR, Teixeira RBC, Di Filippo PA, Manso Filho HC, Alves SR, Santos PVM, Moreira NS. Comparative Trial of Continuous Flow Enteral and Intravenous Fluid Therapy in Horses.. Front Vet Sci 2021;8:686425.
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  4. Bayless RL, Moore AR, Hassel DM, Byer BJ, Landolt GA, Nout-Lomas YS. Equine urinary N-acetyl-β-D-glucosaminidase assay validation and correlation with other markers of kidney injury.. J Vet Diagn Invest 2019 Sep;31(5):688-695.
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  5. Anderson JR, Phelan MM, Clegg PD, Peffers MJ, Rubio-Martinez LM. Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies.. J Proteome Res 2018 Aug 3;17(8):2735-2743.
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