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Anatomia, histologia, embryologia2015; 45(6); 409-417; doi: 10.1111/ahe.12209

Venous Valvular Distribution in the Thoracic and Pelvic Limbs of the Horse.

Abstract: Dysfunction of venous valves can lead to hemodynamic disorders causing venous stasis, which would favour the occurrence of equine laminitis. However, very few studies have investigated venous valves in the horse digit. The purpose of this study was to compare valvular density between thoracic and pelvic limbs and to study the relationship between valvular density of veins and their location, diameter and wall thickness. After dissection, valvular density was calculated based on the number of valves counted in the principal veins of 7 thoracic and 7 pelvic limbs from 7 horses. Our results showed that the valvular density was higher in thoracic limbs, which probably reflects the adaptation to the consequences of hydrostatic pressure. The superficial veins have a higher valvular density that would prevent the varicose risk in the horse. The lower valvular density in the thick veins can be explained by the high density of the smooth muscular cells contained, which would cause an important vasoconstriction via the sympathetic nervous system. The veins with a large diameter also have a lower valvular density; these veins are not exposed to important changes in hydrostatic pressure. Other valvular characteristics may also be involved in the vascular disorders that may be related to the pathophysiology of laminitis.
Publication Date: 2015-09-28 PubMed ID: 26412508DOI: 10.1111/ahe.12209Google Scholar: Lookup
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  • Journal Article

Summary

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The research investigates the distribution of venous valves in horse limbs, and its implications for diseases like laminitis. It essentially compares the valve densities in thoracic and pelvic limbs, and studies the relationship of valve density with the location, diameter, and wall thickness of veins.

Objective and Methodology of the Study

  • The study aimed to extensively examine the presence of venous valves in the limbs of horses, in both thoracic and pelvic limbs.
  • While dysfunction of venous valves can lead to various health disorders in horses, including laminitis, little research has been dedicated to this area.
  • The valvular density was calculated for both types of limbs using a sample of 7 horses, observing and counting the valves in the principal veins. Important factors like vein location, diameter, and wall thickness were also considered.

Findings of the Study

  • The study found that venous valves were more densely distributed in the thoracic limbs than in the pelvic limbs of horses.
  • This higher density of valves in thoracic limbs is likely due to adaptive responses to hydrostatic pressure, implying crucial aspects of equine anatomy and physiology.
  • The research also established a higher valvular density in superficial veins. Increased valve density in these veins potentially provides a protective mechanism against varicose risk, a common vascular disorder in horses.

Implications of Findings

  • The study uncovered that thick veins in horses contain a lower density of venous valves, and this could be attributed to the high presence of smooth muscle cells which trigger considerable vasoconstriction via the sympathetic nervous system.
  • Larger veins, on the other hand, displayed a lower valve density as well, but the reasons could differ. The bigger veins experience relatively steady hydrostatic pressure, thereby requiring fewer venous valves.
  • Altogether, the research suggests that the understanding of venous valve distribution and the associated factors can shed light on vascular disorders in horses, potentially aiding in the diagnosis and prevention of diseases like laminitis.

Cite This Article

APA
Harfoush K, Guintard C, Desfontis JC, Thorin C, Douart C, Mallem MY, Betti E. (2015). Venous Valvular Distribution in the Thoracic and Pelvic Limbs of the Horse. Anat Histol Embryol, 45(6), 409-417. https://doi.org/10.1111/ahe.12209

Publication

ISSN: 1439-0264
NlmUniqueID: 7704218
Country: Germany
Language: English
Volume: 45
Issue: 6
Pages: 409-417

Researcher Affiliations

Harfoush, K
  • Unité d'Anatomie Comparée, Ecole Nationale Vétérinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique - Oniris, BP 40706, 44307, Nantes, France.
  • UPSP 5304 de Physiopathologie Animale et Pharmacologie Fonctionnelle, Ecole Nationale Vétérinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique - Oniris, BP 40706, 44307, Nantes, France.
Guintard, C
  • Unité d'Anatomie Comparée, Ecole Nationale Vétérinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique - Oniris, BP 40706, 44307, Nantes, France.
Desfontis, J C
  • UPSP 5304 de Physiopathologie Animale et Pharmacologie Fonctionnelle, Ecole Nationale Vétérinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique - Oniris, BP 40706, 44307, Nantes, France.
Thorin, C
  • UPSP 5304 de Physiopathologie Animale et Pharmacologie Fonctionnelle, Ecole Nationale Vétérinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique - Oniris, BP 40706, 44307, Nantes, France.
Douart, C
  • Unité d'Anatomie Comparée, Ecole Nationale Vétérinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique - Oniris, BP 40706, 44307, Nantes, France.
Mallem, M Y
  • UPSP 5304 de Physiopathologie Animale et Pharmacologie Fonctionnelle, Ecole Nationale Vétérinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique - Oniris, BP 40706, 44307, Nantes, France.
Betti, E
  • Unité d'Anatomie Comparée, Ecole Nationale Vétérinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique - Oniris, BP 40706, 44307, Nantes, France. eric.betti@oniris-nantes.fr.

MeSH Terms

  • Animals
  • Female
  • Forelimb / blood supply
  • Hemodynamics / physiology
  • Hindlimb / blood supply
  • Horse Diseases / pathology
  • Horses / anatomy & histology
  • Hydrostatic Pressure
  • Ischemia / pathology
  • Ischemia / veterinary
  • Male
  • Myocytes, Smooth Muscle / cytology
  • Vasoconstriction / physiology
  • Venous Valves / anatomy & histology
  • Venous Valves / physiology

Citations

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