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Home / Equine Research Bank / J Rheumatol Suppl / Viscosupplementation: a new concept in the treatment of oste...
The Journal of rheumatology. Supplement1993; 39; 3-9;

Viscosupplementation: a new concept in the treatment of osteoarthritis.

Abstract: Viscosupplementation is a new medical concept that has as its therapeutic goal the restoration of rheological homeostasis in pathological structures such as osteoarthritic joints. When the normal viscoelasticity of a solid tissue compartment or the elastoviscosity of a liquid tissue compartment is decreased under pathological conditions, normal function and regenerative processes are impaired. By introducing viscosupplementary devices, the normal rheological state of such compartments is restored or augmented. These devices stay in the tissue compartment for various periods of time, depending on the nature of the viscosupplement and the pathophysiology of the tissue compartment.
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Publication Date: 1993-08-01 PubMed ID: 8410881
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The article discusses viscosupplementation, a medical approach aimed at restoring the normal rheological state in the structures affected by osteoarthritis, which helps improve function and regeneration in these areas.

Understanding Viscosupplementation

  • Viscosupplementation is a novel therapeutic approach that focuses on re-establishing rheological balance in structures impacted by diseases such as osteoarthritis.
  • The principle of viscosupplementation centers on the understanding that the typical conditions of a tissue compartment (either solid with viscoelastic properties or liquid with elastoviscosity) can be compromised under pathological conditions, hence affecting normal function and tissue regeneration.

Functioning of Viscosupplementary Devices

  • Viscosupplementary devices are medical instruments or implants that contribute to the re-establishment of the standard rheological state in tissue compartments.
  • The purpose of these devices is to restore or enhance the normal viscoelasticity or elastoviscosity, that may have been affected due to diseased conditions.
  • The duration of stay of these devices within the tissue compartment can vary, depending on the type of viscosupplement used and the characteristics of the tissue compartment affected by the disease.

Viscosupplementation and Osteoarthritis

  • The article highlights the potential of viscosupplementation in tackling the complications associated with osteoarthritis.
  • As osteoarthritis is a disease that impacts the normal functioning of joints, restoring the typical rheological conditions can lead to significant improvements in both the function and regeneration process of the affected joints.
  • Though this is a relatively new concept in osteoarthritis treatment, it opens up new possibilities for managing and potentially reversing the degenerative changes brought about by the disease.

Cite This Article

APA
Balazs EA, Denlinger JL. (1993). Viscosupplementation: a new concept in the treatment of osteoarthritis. J Rheumatol Suppl, 39, 3-9.

Publication

The Journal of rheumatology. Supplement
ISSN: 0380-0903
NlmUniqueID: 7806058
Country: Canada
Language: English
Volume: 39
Pages: 3-9

Researcher Affiliations

Balazs, E A
  • Biomatrix Inc., Ridgefield, NJ 07657.
Denlinger, J L

    MeSH Terms

    • Animals
    • Dogs
    • Elasticity / drug effects
    • Homeostasis / drug effects
    • Horses
    • Humans
    • Hyaluronic Acid / administration & dosage
    • Hyaluronic Acid / chemistry
    • Injections, Intra-Articular
    • Osteoarthritis / therapy
    • Rabbits
    • Rheology
    • Synovial Fluid / chemistry
    • Viscosity / drug effects

    Citations

    This article has been cited 152 times.
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