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The Veterinary clinics of North America. Equine practice2025; S0749-0739(24)00094-4; doi: 10.1016/j.cveq.2024.11.001

Vitamin E and Selenium-Related Manifestations of Muscle Disease.

Abstract: Nutritional deficiencies of vitamin E and selenium can occur alone or concurrently. Prolonged and sustained deficiency of either or both nutrients can lead to profound clinical disease. Selenium deficiency can also result in signs of cardiac disease, upper gastrointestinal dysfunction, and abortion or the birth of weak foals. Deficiencies can usually be readily established by evaluating the dietary intake of individuals and by measurement of blood concentrations of these nutrients. Treatment of clinical disease is not always successful and prolonged morbidity and mortality can be encountered; hence, prevention is of the utmost importance.
Publication Date: 2025-01-29 PubMed ID: 39893124DOI: 10.1016/j.cveq.2024.11.001Google Scholar: Lookup
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Summary

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The research article focuses on the effects of prolonged deficiencies in vitamin E and selenium, which can cause severe health issues. It underscores the significance of preventing these deficiencies.

Understanding the Role of Vitamin E and Selenium

  • The research paper starts by explaining the vital role of both vitamin E and selenium in maintaining optimum health. They are essential nutrients that the body cannot produce, hence the necessity of obtaining them from one’s diet or supplements.
  • A deficiency in either or both of these nutrients can have severe consequences on health and lead to significant clinical diseases.

The Impact of Nutrient Deficiencies

  • The article then outlines the specific manifestations that can result from a deficiency in selenium. Some of these consequences include signs of cardiac disease, dysfunction of the upper gastrointestinal tract, and either abortion or delivery of weak foals in horses.
  • Deficiencies in vitamin E can similarly have detrimental effects on health, although the specifics are not elucidated in this abstract.

Diagnosing Deficiencies

  • An essential part of the research study is where they highlight the methods of identifying these deficiencies. This is typically done by examining an individual’s dietary intake of these essential nutrients and measuring their blood concentrations. Through these methods, it is possible to establish if the individual is getting the required levels of selenium and vitamin E.

Treatment and Prevention

  • The abstract cautions that treating clinical diseases arising from nutrient deficiencies is not always guaranteed to be successful. Moreover, prolonged periods of morbidity and even mortality can be experienced as a result of these deficiencies.
  • The research, therefore, underscores the vital importance of preventing these deficiencies in the first place. While it doesn’t elaborate on prevention methods in the abstract, it suggests that these would likely involve ensuring a well-balanced diet rich in these nutrients or using supplements if necessary.

Cite This Article

APA
Finno CJ, McKenzie E. (2025). Vitamin E and Selenium-Related Manifestations of Muscle Disease. Vet Clin North Am Equine Pract, S0749-0739(24)00094-4. https://doi.org/10.1016/j.cveq.2024.11.001

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
PII: S0749-0739(24)00094-4

Researcher Affiliations

Finno, Carrie J
  • Department of Veterinary Population Health & Reproduction, School of Veterinary Medicine, University of California Davis, Room 4206 Vet Med 3A One Shields Avenue, Davis, CA 95616, USA.
McKenzie, Erica
  • Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, 227 Magruder Hall, Corvallis, OR 97331, USA. Electronic address: erica.mckenzie@oregonstate.edu.

Citations

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