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Home / Equine Research Bank / Vet Clin North Am Equine Pract / West Nile encephalitis.
The Veterinary clinics of North America. Equine practice2001; 16(3); 427-441; doi: 10.1016/s0749-0739(17)30087-1

West Nile encephalitis.

Abstract: WNV encephalitis in horses, previously reported in Africa, Asia, and Europe, occurred for the first time in the Western Hemisphere in 1999. The causative agent, WNV, is a flavivirus maintained in nature by a bird-mosquito cycle. The disease in horses is manifested primarily by ataxia of variable severity. Outbreaks of encephalitis may have a case fatality rate in excess of 40%, although this virus infection is inapparent in some horses. Early evidence indicates that WNV has overwintered in the northeastern United States and poses a threat for future disease occurrences in horses. No vaccine is available to protect against WNV infection in horses; disease control is predicated on mosquito abatement.
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Publication Date: 2001-02-24 PubMed ID: 11219341DOI: 10.1016/s0749-0739(17)30087-1Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research focuses on West Nile Virus (WNV) encephalitis in horses. It discusses the virus’ history, its cycle in nature, disease traits, and risk factors, highlighting the lack of effective vaccines and emphasizing the importance of mosquito control for disease prevention.

West Nile Virus

  • The study puts emphasis on West Nile Virus (WNV) encephalitis in horses, which was reported in Africa, Asia, and Europe and first emerged in the Western Hemisphere in 1999.
  • WNV is described as a flavivirus that undergoes a cycle in nature maintained by birds and mosquitoes.

Disease Manifestation and Case Rate

  • The disease’s primary manifestation in horses is identified as ataxia of varying severity. Ataxia refers to a lack of voluntary coordination of muscle movements which typically affects the animals’ gait stability.
  • The research states that outbreaks of the disease can exhibit a case fatality rate exceeding 40%. This implies that in an outbreak scenario, more than 40% of the infected horses might not survive.
  • Interestingly, the research also notes that some horses might show no apparent symptoms of the infection. This could mean that the virus behaves differently in different subjects, or that some horses may have a level of natural resistance or immunity to the disease.

Future Disease Occurrences

  • According to the research, preliminary indications suggest that WNV has overwintered in the northeastern United States, rendering it a potential threat for future outbreaks in horses. Overwintering means that the virus has managed to survive the winter period. This observation supports the plausibility of recurring disease events.
  • In the absence of an available vaccine against WNV infection in horses, the research underscores the significance of mosquito control in the management and mitigation of WNV encephalitis.

Cite This Article

APA
Ostlund EN, Andresen JE, Andresen M. (2001). West Nile encephalitis. Vet Clin North Am Equine Pract, 16(3), 427-441. https://doi.org/10.1016/s0749-0739(17)30087-1

Publication

The Veterinary clinics of North America. Equine practice
ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 16
Issue: 3
Pages: 427-441

Researcher Affiliations

Ostlund, E N
  • Equine and Ovine Viruses Section, Diagnostic Virology Laboratory, National Veterinary Services Laboratories, United States Department of Agriculture , Ames, Iowa, USA.
Andresen, J E
    Andresen, M

      MeSH Terms

      • Animals
      • Antibodies, Viral / analysis
      • Brain / virology
      • Disease Outbreaks / veterinary
      • Horse Diseases / diagnosis
      • Horse Diseases / epidemiology
      • Horse Diseases / therapy
      • Horses
      • Mosquito Control
      • United States / epidemiology
      • West Nile Fever / diagnosis
      • West Nile Fever / epidemiology
      • West Nile Fever / therapy
      • West Nile Fever / veterinary

      Citations

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