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Home / Equine Research Bank / Viruses / West nile virus antibody prevalence in horses of Ukraine.
Viruses2013; 5(10); 2469-2482; doi: 10.3390/v5102469

West nile virus antibody prevalence in horses of Ukraine.

Abstract: West Nile virus (WNV) is a mosquito-borne virus of global importance. Over the last two decades, it has been responsible for significant numbers of cases of illness in humans and animals in many parts of the world. In Ukraine, WNV infections in humans and birds were first reported more than 25 years ago, yet the current epidemiological status is quite unclear. In this study, serum samples from over 300 equines were collected and screened in order to detect current WNV activity in Ukraine with the goal to estimate the risk of infection for humans and horses. Sera were tested by enzyme-linked immunosorbent assay (ELISA) and virus neutralization assay (NT) to detect WNV-specific antibodies. The results clearly revealed that WNV circulates in most of the regions from which samples were obtained, shown by a WNV seroprevalence rate of 13.5% of examined horses. This is the first topical report indicating the presence of WNV infections in horses in Ukraine, and the results of this study provide evidence of a widespread WNV circulation in this country.
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Publication Date: 2013-10-04 PubMed ID: 24100889PubMed Central: PMC3814598DOI: 10.3390/v5102469Google Scholar: Lookup
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  • Journal Article
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  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research investigates the presence of the West Nile Virus (WNV) in horses in Ukraine, a mosquito-borne virus of global concern. Using serum samples from over 300 horses, the study reveals a significant WNV prevalence in Ukraine, marking the first study to indicate WNV infections in horses in this country.

Introduction

  • The study revolves around the West Nile Virus (WNV), which is a significant global health concern transmitted through mosquitos.
  • While WNV has been confirmed in humans and birds in Ukraine over 25 years ago, the present epidemiological situation for horses remains largely unclear.

Methodology

  • Over 300 equines (horses, donkeys, etc.) were used in this study, from which serum samples were collected and screened.
  • The goal of this screening was to assess the current WNV activity in Ukraine and to estimate the infection risk for both humans and horses.
  • The sera were analyzed using an enzyme-linked immunosorbent assay (ELISA) and a virus neutralization assay (NT), both commonly used to detect WNV-specific antibodies.

Findings

  • The study revealed that the West Nile Virus circulates in many of Ukraine’s regions where the samples were obtained.
  • An estimated 13.5% of the examined horses showed signs of WNV infection, indicating a significant WNV prevalence.
  • This marks the first report of WNV infections in horses in Ukraine, highlighting the need for further surveillance and preventative measures.

Conclusion

  • Based on the results of the study, there is abundant evidence of widespread WNV circulation in Ukraine.
  • This finding raises substantial concerns regarding the risk of WNV transmission to human populations and recommends further comprehensive studies into the health implications of this wide WNV prevalence.

Cite This Article

APA
Ziegler U, Skrypnyk A, Keller M, Staubach C, Bezymennyi M, Damiani AM, Osterrieder N, Groschup MH. (2013). West nile virus antibody prevalence in horses of Ukraine. Viruses, 5(10), 2469-2482. https://doi.org/10.3390/v5102469

Publication

Viruses
ISSN: 1999-4915
NlmUniqueID: 101509722
Country: Switzerland
Language: English
Volume: 5
Issue: 10
Pages: 2469-2482

Researcher Affiliations

Ziegler, Ute
  • Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, Südufer 10, D-17493 Greifswald-Insel Riems, Germany. martin.groschup@fli.bund.de.
Skrypnyk, Artem
    Keller, Markus
      Staubach, Christoph
        Bezymennyi, Maksym
          Damiani, Armando M
            Osterrieder, Nikolaus
              Groschup, Martin H

                MeSH Terms

                • Animals
                • Antibodies, Neutralizing / blood
                • Antibodies, Viral / blood
                • Enzyme-Linked Immunosorbent Assay
                • Horse Diseases / epidemiology
                • Horse Diseases / virology
                • Horses
                • Neutralization Tests
                • Seroepidemiologic Studies
                • Ukraine / epidemiology
                • West Nile Fever / epidemiology
                • West Nile Fever / veterinary
                • West Nile Fever / virology
                • West Nile virus / immunology

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                Citations

                This article has been cited 6 times.
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