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The Veterinary clinics of North America. Equine practice2023; 39(2); 381-397; doi: 10.1016/j.cveq.2023.03.004

What Is the Microbiota and What Is Its Role in Colic?

Abstract: The fecal microbiome of the horse is reflective of the large colon and plays an important role in the health of the horse. The microbes of the gastrointestinal tract digest fiber and produce energy for the host. Healthy horses have Firmicutes, Bacteroidetes, and Verrucromicrobia as the most common phyla. During gastrointestinal disease such as colic or colitis, the microbiome shows less diversity and changes in bacterial community composition.
Publication Date: 2023-04-28 PubMed ID: 37121786DOI: 10.1016/j.cveq.2023.03.004Google Scholar: Lookup
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Summary

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The research article discusses the role of the horse’s fecal microbiome, specific bacterial species and their associations with gastrointestinal diseases like colic and colitis. Major findings indicate a decrease in the diversity of the microbiome and shifts in bacterial communities during these diseases.

The Microbiota and its Function

  • The gastrointestinal tract of a horse is home to a diverse community of microorganisms commonly known as the microbiota. This includes bacteria, viruses, fungi and other microscopic inhabitants.
  • The composition of this community plays a critical role in the overall health of the horse. The microbiota aids in the digestion of food, specifically by breaking down fibers that the horse itself cannot digest, and converting it into energy.
  • The default composition of a healthy horse’s microbiota consist of mainly three bacterial phyla – Firmicutes, Bacteroidetes, and Verrucromicrobia.

The Microbiota and Diseases

  • However, this research highlights that the health and diversity of the microbiota is significantly affected during a gastrointestinal disease such as colic or colitis. These conditions result in a decreased diversity and an altered composition of the bacterial community within the microbiota.
  • Colic is a condition that leads to severe abdominal discomfort in horses. On the other hand, colitis is an inflammation of the colon. Both these conditions, as the research suggests, lead to changes in the usual bacterial community composition.
  • The study suggests the microbiota and the balance within its microbial community is essential for maintaining equine health, any disruption or imbalance can possibly result in disease.

Conclusion

  • Over the course of this study, a better understanding of the link between microbiota and gastrointestinal diseases has been gained. This information can be utilized towards formulating preventive measures and optimizing the treatment for conditions like colic and colitis, ultimately improving the healthcare strategies for horses.

Cite This Article

APA
Arnold CE, Pilla R. (2023). What Is the Microbiota and What Is Its Role in Colic? Vet Clin North Am Equine Pract, 39(2), 381-397. https://doi.org/10.1016/j.cveq.2023.03.004

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 39
Issue: 2
Pages: 381-397

Researcher Affiliations

Arnold, Carolyn E
  • School of Veterinary Medicine, Texas Tech University, 7671 Evans Street, Amarillo, Texas 79106, USA. Electronic address: Carolyn.Arnold@ttu.edu.
Pilla, Rachel
  • Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Texas A&M University, College Station, TX, USA.

MeSH Terms

  • Horses
  • Animals
  • Colic / veterinary
  • Horse Diseases / microbiology
  • Microbiota
  • Bacteria
  • Feces / microbiology

Citations

This article has been cited 3 times.
  1. Carvalho BVL, de Souza MCN, Avanza MFB, Teixeira RBC, Silva JRB, da Silva Cardoso T, Novais LGES, de Oliveira Monteiro FD, Viana RB, Monteiro BM, Teixeira PPM, Filho JDR. Laparoscopically assisted cecal cannulation in standing horses. Front Vet Sci 2025;12:1717140.
    doi: 10.3389/fvets.2025.1717140pubmed: 41585512google scholar: lookup
  2. Schank N, Cottone A, Wulf M, Seiter K, Thomas B, Miller LMJ, Anderson SL, Sahyoun A, Abidi AH, Kassan M, Verma A. The Role of Short-Chain Fatty Acids (SCFAs) in Colic and Anti-Inflammatory Pathways in Horses. Animals (Basel) 2025 Dec 3;15(23).
    doi: 10.3390/ani15233482pubmed: 41375540google scholar: lookup
  3. Żak-Bochenek A, Drábková Z, Sergedaite V, Siwińska N, Bajzert J, Pasak D, Chełmońska-Soyta A. Fecal Secretory Immunoglobulin A and Lactate Level as a Biomarker of Mucosal Immune Dysfunction in Horses With Colic. J Vet Intern Med 2025 May-Jun;39(3):e70073.
    doi: 10.1111/jvim.70073pubmed: 40145309google scholar: lookup