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Immune Supplements for Horses

View a list of immune supplements for horses in Mad Barn’s Equine Feed Database. Immune supplements are products formulated with nutrients or functional ingredients that help support normal immune function, antioxidant status, and overall health. Common ingredients may include vitamins, trace minerals, omega-3 fatty acids, probiotics, yeast products, antioxidants, and plant-based compounds. Compare brands, ingredients, and nutritional profiles to choose immune support products for your horse.

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Immune Supplements
3:1 Zinc Copper (Mad Barn)
HealthHealth
Hoof HealthHoof Health
Mineral BalanceMineral Balance
Skin + HairSkin + Hair
Mad Barn’s 3:1 Zinc Copper Powder is an organic trace mineral supplement for horses, providing zinc and copper proteinates in a 3:1 ratio. These chelated trace minerals are formulated for improved absorption and help support hoof health, connective tissue integrity, skin condition and coat quality.
Jiaogulan (Mad Barn)
AntioxidantAntioxidant
CirculationCirculation
Hoof HealthHoof Health
IngredientIngredient
Jiaogulan powder supports circulation, muscle function, and respiratory health in horses. Jiaogulan has been shown to increase blood flow to horses' hooves.
L-Lysine (Mad Barn)
Amino AcidAmino Acid
ImmunityImmunity
IngredientIngredient
JointsJoints
Lysine is an essential amino acid that is important for forming strong collagen bonds. Lysine is the most commonly deficient amino acid in equine diets.
MagneChrome+ (Mad Barn)
AntioxidantAntioxidant
EnergyEnergy
Metabolic SyndromeMetabolic Syndrome
Mineral BalanceMineral Balance
MagneChrome+ from Mad Barn (formerly sold under the name IR Supplement) is a magnesium and chromium supplement for IR Horses. This supplement provides antioxidant and support of normal insulin sensitivity which is critical for horses with metabolic conditions such as insulin resistance, laminitis and PPID.
Natural E/Organic Se (Mad Barn)
AntioxidantAntioxidant
Organic Trace MineralsOrganic Trace Minerals
RecoveryRecovery
VitaminsVitamins
Natural E/Organic Se is a pelleted supplement providing organic Selenium yeast and natural Vitamin E. These two nutrients are important antioxidants that support muscle function and anti-inflammatory pathways.
NOCR (Mad Barn)
AntioxidantAntioxidant
PerformancePerformance
RespiratoryRespiratory
StaminaStamina
Mad Barn's NOCR is a respiratory supplement intended to help with lung health and function. It contains antioxidants and is also meant to assist with performance, cardiovascular health and immune function.
Spirulina (Mad Barn)
HealthHealth
ImmunityImmunity
IngredientIngredient
RespiratoryRespiratory
Spirulina platensis is a blue-green algae that is rich in protein, fatty acids, vitamins, and minerals. Spirulina provides nutritional support for the skin, respiratory function, and immune system in horses.
Trace Mineral Pak (Mad Barn)
Coat QualityCoat Quality
ExerciseExercise
Hoof HealthHoof Health
Organic Trace MineralsOrganic Trace Minerals
Trace Mineral Pak from Mad Barn is a balanced equine supplement providing 100% organic (chelated) trace minerals. Ingredients include selenium, zinc, copper, and manganese.
w-3 Oil (Mad Barn)
Coat QualityCoat Quality
FatFat
JointsJoints
Omega 3-6-9Omega 3-6-9
w-3 Oil by Mad Barn is an essential fatty acid supplement fortified with the omega-3 DHA and natural Vitamin E. W-3 Oil helps to support joint health, coat quality, cardiovascular health and weight maintenance.
Immune Plus (Omega Alpha)
AntioxidantAntioxidant
HerbHerb
ImmunityImmunity
StressStress
Omega Alpha Immune Plus™ is an equine supplement containing astragalus, echinacea, ashwagandha, Siberian ginseng, and reishi mushroom. It is purported to support immune function.
Immunox (Equine Elixirs)
AntioxidantAntioxidant
Competition HorsesCompetition Horses
ImmunityImmunity
StressStress
Immunox by Equine Elixirs is a supplemented intended to boost natural immune function in horses undergoing intense exercise, travel or exposure to sick horses by providing Vitamin E, Vitamin C, Vitamin A and Selenium.
In-SYNC 4 (MVP)
Blood CellsBlood Cells
Coat QualityCoat Quality
ImmunityImmunity
MuscleMuscle
In-SYNC 4 from MVP is a supplement intended to support muscle function, immune health, blood cell production, and coat quality. It contains B-vitamins, amino acids, and vitamins.
Karbo Combo + (Karbo Essentials)
HealthHealth
ImmunityImmunity
Organic Trace MineralsOrganic Trace Minerals
YeastYeast
Karbo Combo+ by Karbo Essentials is a comprehensive pelleted nutritional supplement formulated to support and strengthen the immune system in horses and other animals.
Lami-Free (Dodson & Horrell)
CirculationCirculation
HerbHerb
Hoof HealthHoof Health
ImmunityImmunity
Lami-Free from Dodson & Horrell is an all-natural horse supplement that is intended to improve circulation, immune function, and hoof health. Lami-Free contains herbs such as nettle and rosehips.
Lifeline Equine (Stride Animal Health)
HealthHealth
ImmunityImmunity
PerformancePerformance
RecoveryRecovery
Lifeline Equine is a pelleted supplement intended to support overall equine health. This supplement contains porcine plasma, intended to support equine wellbeing.
LifeLine+ Equine (Bluebonnet Feeds)
Gut HealthGut Health
HealthHealth
ImmunityImmunity
RespiratoryRespiratory
LifeLine+ Equine by Bluebonnet is a pelleted nutritional supplement formulated to support respiratory, digestive, reproductive, and joint health in horses. It features bioactive proteins derived from plasma and yeast, which are included to promote overall wellness and strengthen immune function.
LoosenUP (Kelato)
AntioxidantAntioxidant
Mineral BalanceMineral Balance
RecoveryRecovery
VitaminsVitamins
LoosenUP from Kelato is a supplement that provides antioxidants in a blend of vitamin E and C, selenium, magnesium, and chromium. It is meant to assist horses during illness, stress, and recovery from injuries or exercise.
Lung+ (Advanced Equine Nutrition)
Gut HealthGut Health
HealthHealth
ImmunityImmunity
RespiratoryRespiratory
Lung+ by Advanced Equine Nutrition is intended to support allergies and respiratory function. It contains spirulina and jiaogulan.
Maximum E & SE (Cox Vet Lab)
AntioxidantAntioxidant
ImmunityImmunity
MuscleMuscle
VitaminsVitamins
Maximum E & SE is a liquid supplement intended to support healthy muscle, nerve, and reproduction functions. It is ideal for performance and working horses.
Mucolyte (St.Hippolyt)
HealthHealth
ImmunityImmunity
NutritionNutrition
RespiratoryRespiratory
Mucolyte by St.Hippolyt is a supplement intended to support horse's airways and overall immune function.
Mud Heel (Dodson & Horrell)
Coat QualityCoat Quality
HerbHerb
ImmunityImmunity
JointsJoints
Mud Heel from Dodson & Horrell is an herbal supplement that supports healthy skin growth, maintenance, and immunity and encourages mobility. This supplement is intended for horses and ponies exposed to muddy conditions.
Optimum GI (BioStar)
DigestionDigestion
Gut HealthGut Health
HealthHealth
ImmunityImmunity
Optimum GI from BioStar is a powdered gut health supplement. Optimum GI contains vitamins, antioxidants, minerals and fatty acids intended to support digestion and overall horse health.
Platinum Dermal Support (Platinum Performance)
Coat QualityCoat Quality
ImmunityImmunity
NutrientsNutrients
Skin + HairSkin + Hair
Platinum Dermal Support by Platinum Performance is a supplement intended to support skin, hair and coat health. It can also aid in immune system health.
Pulmo-Care (Probiotech)
HealthHealth
ImmunityImmunity
NutritionNutrition
RespiratoryRespiratory
Pulmo-Care from Probiotech is a respiratory supplement that is intended to assist with the moisture balance in the nose, throat, and lungs. It contains selenium and is meant to support the immune system.
Pulmonaire (Herbs for Horses)
AntioxidantAntioxidant
HealthHealth
ImmunityImmunity
RespiratoryRespiratory
Pulmonaire is an anti-oxidant supplement purported to support immune function and suppress allergic reactions. It consists of aniseed, omega-3 oil, and spirulina (blue green algae).
Pure Allergy Relief (Twenty Four Carrots)
AntioxidantAntioxidant
HealthHealth
HerbHerb
ImmunityImmunity
Pure Allergy Relief by Twenty Four Carrots is a natural herbal supplement formulated to support healthy immune and respiratory function. It is designed to help reduce the symptoms associated with seasonal and environmental allergies.
Resist + Vit C (Cavalor)
AntioxidantAntioxidant
HealthHealth
ImmunityImmunity
VitaminsVitamins
Resist + Vit C by Cavalor is a powdered immune support supplement formulated with herbs and antioxidants to enhance the horse's natural defenses. It is ideal for horses that travel frequently or are regularly exposed to other horses.
Shake Relief (NAF Equine)
ImmunityImmunity
Mineral BalanceMineral Balance
RespiratoryRespiratory
StressStress
Shake Relief by NAF Equine is a powdered immune supplement that contains antioxidants, herbs, and magnesium which is meant to support a calm, confident demeanor.
SmartBreathe Ultra Pellets (SmartPak)
ImmunityImmunity
IngredientIngredient
PerformancePerformance
RespiratoryRespiratory
SmartBreathe Ultra Pellets from SmartPak is a pelleted respiratory supplement for horses. SmartBreathe Ultra is formulated with spirulina, MSM, and grape seed extract intended to help horses with respiratory issues.
SmartImmune Pellets (SmartPak)
HealthHealth
HerbHerb
ImmunityImmunity
NutritionNutrition
SmartImmune Pellets from SmartPak is a pelleted equine supplement. SmartImmune Pellets is formulated with astragalus, ginseng and golden root intended to support immune function in horses. This supplement is intended to help horses manage stress.
SmartVite Perform Senior (SmartPak)
ImmunityImmunity
Mineral BalanceMineral Balance
SeniorSenior
VitaminsVitamins
SmartVite Perform Senior is a vitamin and mineral supplement for working senior horses. It is also intended to support immunity and provide antioxidants.
Spine & Nerve (ImmuBiome)
AntioxidantAntioxidant
HerbHerb
RecoveryRecovery
StressStress
Spine & Nerve by ImmuBiome is a powdered supplement that is meant to aid with spinal support, neurological pathways, neurovascular support, and supports joint mobility.
Spirulina Chia (Stable Feed)
AntioxidantAntioxidant
HealthHealth
HerbHerb
ImmunityImmunity
Spirulina Chia from Stable Feed is a powdered supplement for horses. This supplement is intended to promote the healing of skin issues in horses.
SU-PER Anti-Oxidant Powder (Gateway Products)
AntioxidantAntioxidant
Mineral BalanceMineral Balance
NutrientsNutrients
VitaminsVitamins
SU-PER Anti-Oxidant Powder by Gateway Products is an anti-oxidant supplement anti-oxidant to support general health, energy production, and immune response for horses under stress or recovering from illness.
SU-PER C Powder (Gateway Products)
Amino AcidAmino Acid
RecoveryRecovery
StressStress
VitaminsVitamins
SU-PER C Powder by Gateway Products is a supplement that contains vitamin C that can provide anti-oxidant support to horses. It may help support respiratory health, cardiovascular function, and the immune system.
SU-PER DMG 3000 Liquid (Gateway Products)
EnergyEnergy
ImmunityImmunity
MuscleMuscle
RecoveryRecovery
SU-PER DMG 3000 Liquid is a liquid supplement designed to support cardiovascular, muscle, and immune function. It boosts these functions and is a good choice for performance horses, older horses, and horses in recovery.
SU-PER DMG 3000 Powder (Gateway Products)
ExerciseExercise
ImmunityImmunity
MuscleMuscle
PerformancePerformance
SU-PER DMG 3000 Powder is a powder supplement designed to support cardiovascular, muscle, and immune function. It boosts these functions and is a good choice for performance horses, older horses, and horses in recovery.
SU-PER E-Se Pellets (Gateway Products)
AntioxidantAntioxidant
ImmunityImmunity
Mineral BalanceMineral Balance
VitaminsVitamins
SU-PER E-Se Pellets by Gateway Products is a supplement that supports immune function, muscle function, and optimal recovery. Vitamin E and selenium are good antioxidants to aid in the recovery of sore muscles.
SU-PER E-Se Powder (Gateway Products)
AntioxidantAntioxidant
ImmunityImmunity
Mineral BalanceMineral Balance
VitaminsVitamins
SU-PER E-Se Powder is a supplement that supports immune function, muscle function, and optimal recovery. Vitamin E and selenium are good antioxidants to aid in the recovery of sore muscles.
SU-PER Grape Seed Extract Powder (Gateway Products)
AntioxidantAntioxidant
HealthHealth
HerbHerb
ImmunityImmunity
SU-PER Grape Seed Extract Powder is an antioxidant supplement to improve circulation, respiratory health, and the immune system. This supplement would benefit performance horses, senior horses, or horses recovering from illness or injury.
SU-PER ImmunoBOOST Powder (Gateway Products)
AntioxidantAntioxidant
HerbHerb
ImmunityImmunity
NutrientsNutrients
SU-PER ImmunoBOOST Powder by Gateway Products is an immune supplement of anti-oxidants, vitamins and minerals, and herbal extracts. This supplement is for seniors, performance, and horses under consistent stress.
Support One (Pureform)
AntioxidantAntioxidant
JointsJoints
Mineral BalanceMineral Balance
VitaminsVitamins
Pureform Support One is an equine supplement formulated to support joint, bone, and immune health. It contains Glucosamine, MSM, amino acids, complete vitamins, trace minerals, and anti-oxidants.
Suppressol (Figuerola Laboratories)
AntioxidantAntioxidant
HealthHealth
HerbHerb
NutrientsNutrients
Suppressol by Figuerola Laboratories is an immune supplement designed for all working classes of horses. It is formulated with antioxidants, vitamins and minerals.
Total Immune Blast (Ramard)
Bone HealthBone Health
ImmunityImmunity
NutrientsNutrients
RespiratoryRespiratory
Total Immune Blast from Ramard is a supplement that can be given to horses or foals to boost immunity. It is meant to help horses recover from illnesses or help assist in preventing them. It can also help fight free radicals, help with breathing, and develop bone marrow.
Turmeric 2X (MVP)
AntioxidantAntioxidant
HealthHealth
HerbHerb
NutrientsNutrients
Turmeric 2X by MVP is a powdered turmeric supplement that intends to support the immune system, inflammatory response and neuro function. It also contains MSM may lessen the inflammation.
Ulc-R-Aid (AniMed)
Gut HealthGut Health
ImmunityImmunity
Mineral BalanceMineral Balance
UlcersUlcers
Ulc-R-Aid from AniMed is a powdered supplement that is supposed to support horses prone to gastric ulcers. It aids in immune function and contains Colostrashield.
Ulceraser (Equine Elixirs)
FlavorFlavor
Gut HealthGut Health
ImmunityImmunity
UlcersUlcers
Ulceraser from Equine Elixirs is a palatable supplement that is meant to support the entire digestive tract of horses. Mainly, it is used for horses prone to digestive upset or ulcers from training, traveling, stress, or diet related issues. It can also support immunity.
UlcerPLUS (Enviro Equine)
AntioxidantAntioxidant
Gut HealthGut Health
PerformancePerformance
UlcersUlcers
UlcerPLUS by Enviro Equine is a liquid supplement containing Sea Buckthorn berry pulp and pure Aloe Vera leaf juice. It is intended to support digestive and immune health in horses.
UltraCruz Equine Antioxidant (Santa Cruz Animal Health)
AntioxidantAntioxidant
HealthHealth
Mineral BalanceMineral Balance
VitaminsVitamins
UltraCruz Equine Antioxidant is a pelleted vitamin and mineral supplement for horses. It provides the antioxidants selenium, vitamin C and vitamin E to potentially protect cells from oxidative damage.
UltraCruz Equine Garlic Flakes (Santa Cruz Animal Health)
HealthHealth
IngredientIngredient
NutrientsNutrients
NutritionNutrition
UltraCruz Equine Garlic Flakes provides 10 grams of dehydrated garlic flakes per serving. Garlic is purported to support respiratory health and the immune system in horses.
UltraCruz Equine Skin and Allergy Supplement (powder) (Santa Cruz Animal Health)
HealthHealth
NutrientsNutrients
Omega 3-6-9Omega 3-6-9
Skin + HairSkin + Hair
UltraCruz Equine Skin and Allergy Supplement is a powdered supplement intended to support the immune system of horses. It is formulated with the omega-3 fatty acid DHA, quercetin, and calf thymus protein to reduce reactions to allergens.
Uveitis Formula (The Equine Edge)
AntioxidantAntioxidant
HealthHealth
ImmunityImmunity
VisionVision
Uveitis Formula from Total Horse Health is a powdered supplement intended for horses with uveitis. This supplement contains jalapeno, turmeric and echinacea which are intended to manage symptoms of uveitis in horses.
Vitality Super Greens (Yucc’ It Up!)
HealthHealth
HerbHerb
ImmunityImmunity
VitaminsVitamins
Vitality Super Greens from Yucc' It Up! is a powdered herbal multi-vitamin supplement. Vitality Super Greens contains kelp, nettle leaves, red raspberry leaves and spirulina.
Vitamin C (Equestrizone)
AntioxidantAntioxidant
Competition HorsesCompetition Horses
ImmunityImmunity
IngredientIngredient
Vitamin C from Equestrizone is an antioxidant which can be fed to horses at times of stress or illness. It is from Equestrizone provides joint and cardiovascular support for horses and ponies.
Vitamin C Powder (Cox Vet Lab)
AntioxidantAntioxidant
ImmunityImmunity
RespiratoryRespiratory
VitaminsVitamins
Vitamin C Powder by Cox Vet Lab is a vitamin powder supplement intended to help support a horse's immune system. It may also be beneficial to aid in ulcerated tissue healing.
Vitamin C Pure (Basic Equine Nutrition)
AntioxidantAntioxidant
IngredientIngredient
NutrientsNutrients
VitaminsVitamins
Vitamin C (ascorbic acid) is a water-soluble vitamin that supports the immune system. It is supplemented in the equine diet to promote peak performance and support recovery from illness.
Vitamin E/C (Stride Animal Health) – [Discontinued]
AntioxidantAntioxidant
HealthHealth
ImmunityImmunity
VitaminsVitamins
This supplement from Stride Animal Health provides antioxidants by containing vitamin E and vitamin C. This assists the body in maintaining healthy tissues and cells and increasing immunity.
Yoder’s Horse Powder (Yoder’s)
AntioxidantAntioxidant
HealthHealth
HerbHerb
ImmunityImmunity
Yoder's Horse Powder is a powdered supplement intended to boost horses' immune system. This supplement contains a mixture of herbs intended to help horses who are troubled with respiratory issues.
Yucc’ It Up! Original Formula (Yucc’ It Up!)
Gut HealthGut Health
HealthHealth
HerbHerb
ImmunityImmunity
Yucc' It Up! Original Formula from Yucc' It Up! is intended to provide whole-body support for horses. Yucc' It Up! Original Formula contains yucca schidegera herb which is intended to support intestinal health.
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