Annales de recherches vétérinaires. Annals of veterinary research.
Discontinued
Publisher:
Institut national de la recherche agronomique.. Paris : Institut National De La Recherche Agronomique
Frequency: Quarterly
Country: France
Language: fre
Author(s):
Institut national de la recherche agronomique (France)
Start Year:1970 - 1992
Identifiers
| ISSN: | 0003-4193 (Print) 0003-4193 (Linking) |
| NLM ID: | 1267230 |
| (DNLM): | A33330000(s) |
| (OCoLC): | 01481288 |
| Coden: | ARCVBP |
| Classification: | W1 AN381 |
Production of monoclonal antibodies against equine influenza: application to a comparative study of various strains of the virus. Monoclonal antibodies (Mo Abs) were prepared against influenza/A/equine/Prague/1/56 (H7N7) and influenza/A/equine/Miami/1/63 (H3N8) reference strains of equine influenza virus. These monoclonals were tested against the 2 reference strains, 8 field strains of equine influenza virus, 3 human influenza viruses possessing the H3 hemagglutinin, and one virus of human origin possessing the H1 hemagglutinin. Two antibodies were obtained in one fusion against the Prague/1/56 strain and reacted only with this strain. Four anti/A/equine/Miami/1/63 Mo Abs were obtained in one fusion. They differentiated ...
[Experimental equine fascioliasis: evolution of serologic, enzymatic and parasitic parameters]. Three, four, and one horses were respectively infected with 100, 1,000, and 5,000 metacercariae of Fasciola hepatica. Six of them were reinfected 38 weeks later with 1,000 metacercariae each. Specific antibodies assayed by counter-electrophoresis, passive hemagglutination and ELISA tests appeared three to six weeks post-infection and peaked 10 to 17 weeks post-infection. Horses infected by 1,000 metacercariae and more showed 17.6% of positive samples by counter-electrophoresis, 49.2% by ELISA, and 75.6% by passive hemagglutination. Plasma glutamate dehydrogenase and gamma-glutamyltransferase l...
[Establishment of a re-entrant ileo-cecal fistula in Equidae]. A re-entrant cannulation of the digestive tract was performed in Equidae (ponies and donkeys) between the distal extremity of the ileum and the base of the caecum. The operative technique was conceived to avoid risks of infection of the peritoneal cavity: the openings of the ileum and of the caecum were achieved only after the closure of the abdominal wall incision. Two donkeys were still alive ten months after the operation. This method can provide a convenient model for digestibility studies in Equidae, particularly for assessment of the pre-caecal digestibility.
[Flunixin and its use in horses]. Flunixin is a non-steroidal anti-inflammatory agent, with a potent analgesic activity and a slight toxicity. It is largely used in horses, in the form of meglumine salt, for the treatment of inflammatory diseases or colics, and often identified in dopage cases. Physical and chemical properties of the drug, its pharmacological and toxicological properties, and its use in equine species are depicted.
Radioimmunoassay of 19 nor testosterone. Evidence of its secretion by the testis of the stallion. Antiserum has been raised in rabbits treated with a 19 nor testosterone-hemisuccinate-bovine-serum-albumin conjugate and used for the development of a specific RIA of plasma 19 nor testosterone. Plasma samples are drawn from testicular and jugular veins of stallions during castration under general anesthesia. Results demonstrate a testicular secretion of 19 nor testosterone and a stress inhibition of this secretion correlatively with stress inhibition of testosterone secretion.
Uraemia in the mare: effects of seasonal variations, of energy level of the diet and individual differences. Uraemia variations in the heavy breed mare were studied in different situations. A study with 35 mares during an entire grazing season was conducted. The mean uraemia varied between 48.5 and 67.5 mg/100 ml plasma, with season and type of grass. The highest values were found with first-cycle pasture grass. Uraemia was lower with winter diets: 28.6 to 36.0 mg/100 ml. A study using 15 mares fed isonitrogenous diets based on hay or straw, and concentrates offered two different levels, between two months before and 8 days after foaling, showed that the physiological stage had a very moderate effect...
[Chronopharmacokinetics of phenylbutazone in the horse. Application to antidoping control]. Chronopharmacokinetics of intravenous phenylbutazone in the horse was studied with the aim of antidoping control. Among parameters studied, the single one which seemed to depend on circadian rhythm was the elapsed time between the injection and the plasmatic peak. There was no relationship between the injection time and the both parameters: half-life and time required to reach the forensic level of 4 micrograms/ml. This later, and oxyphenbutazone/phenylbutazone ratio, should depend on individual factors. Therefore, the injection time should not be a main parameter for the phenylbutazone evalua...
[Experimental reproduction of lactic acidosis in the pony]. One pony has been subjected to the intravenous injections of L-lactic acid. Two other ponies have been trained to intracaecal administration of L-lactic acid or sucrose. The obtained results show that: Intravenous injection of lactic acid increases the concentration of histamin and lactic acid, decreases the level of magnesium and reduces the pressure of carbon dioxide in the blood (the control animals and the treated animals) without the clinical symptoms of lactic acidosis. Intracaecal administration of lactic acid induces a high liberation of histamin in the caecum (the control animals and ...
[Variations in plasma components in lactating mares at late pregnancy-early lactation (author’s transl)]. In an experiment comparing pregnant then lactating mares with dry non-pregnant mares, the changes in plasma components were studied as indicators of the metabolic utilization of energy (glucose, non-esterified fatty acids, beta-hydroxybutyrate), nitrogen (urea, proteins) or minerals (calcium, phosphorus, magnesium). The mares were fed daily 2 kg concentrate and hay ad libitum. Beta-hydroxybutyrate, magnesium and to a lesser extent glucose were the only constituents whose levels were affected within the period starting one month before and ending one month after foaling. The increase in food in...
[A serological study of the contagious equine metritis: comparison between indirect immunofluorescence, slow agglutination and complement fixation techniques (author’s transl)]. Serological response of pony mares to contagious equine metritis is studied comparing three techniques: slow agglutination, complement fixation and indirect immunofluorescence. Sera were taken from pony mares vaccinated with a heat inactivated suspension of Haemophilus equigenitalis, from experimentally-infected pony mares and from healthy horses. All three reactions detected antibodies in vaccinated and infected animals. The highest titers are observed with vaccinated mares. Titers are low in infected animals. Antibodies detected by indirect immunofluorescence appeared sooner and persisted lo...
Anthelmintic treatment of equids: capabilities and limitations. Critical tests of nine anthelmintic agents on ponies. A number of good anthelmintic drugs are currently available which eliminate gastrointestinal nematodes of equids with over 90% success. This is shown by comparing results of critical tests conducted with 9 anthelmintic agents on ponies using the following dosages: 19 mg/kg for Pyrantel embonate, 10 mg/kg for Oxfendazole, 10 mg/kg for Mebendazole, 5 mg/kg for Albendazole, 40 mg/kg for Dichlorvos, 44 mg/kg for Thiabendazole, 7.5 mg/kg, for Fenbendazole, 20 mg/kg for Cambendazole and 7 mg/kg for Parbendazole. From 6 to 9 ponies were treated with each of these anthelmintic agents. Based on total a...
[Bacteriological studies of Haemophilus equigenitalis Taylor 1978, the causative organism of contagious equine metritis 1977 (author’s transl)]. The cultural, biochemical, antigenic and antibiotic susceptibility characteristics of 17 strains of Haemophilus equigenitalis, the causative organism of contagious equine metritis (CEM), were studied. Biochemical characteristics were investigated using both conventional method and the API ZYM system of enzyme detection. The biochemical profile of the H. equigenitalis strains was unique and differed from the other bacterial species studied under the same experimental conditions (H. influenzae and H. parainfluenzae, B. abortus and B. melitensis, P. multocida, A. calcoaceticus). The required X an...
[Blood serum biochemistry of ponies (author’s transl)]. A wide blood serum biochemical profile, concerning especially blood lipids has been performed in 31 apparently healthy Shetland and Potiock ponies. These blood standard values will be useful for studies on ponies' hyperlipemia.
Equine leptospirosis with some clinical observations. In a serologic survey on equine leptospirosis in Egypt, the following incidences of leptospiral serosensitivity were found: 1. Hospitalised horses 65/113 (57.5 %). 2. Hospitalised donkeys 90/125 (72.0 %). 3. Apparently healthy horses 21/72 (29.1 %). Sera of these animals were mostly reacting to serotypes butembo, pomona, icterohemorragiae, and grippotyphosa. Equine in Egypt are close animals to humans and may constitute a potential source of leptospiral infection. From the clinical point of view, it is very possible that ocular, hoof lesions and icterus in equines would be expected with leptos...
[Contribution to the antigenic study of influenza viruses in animals. I.–Neuraminidase of the equine influenza viruses (author’s transl)]. From the Revised Nomenclature of WHO, the fowl influenza virus A/Duck/Ukraine/63 (Hav7 Neq2) has the same neuraminidase as the equine virus A/equi 2/Miami/63 (Heq2 Neq2); the A/Chicken Germany "N"/49 virus has the same neuraminidase as the equine virus A/equi 1/Prague/56. A comparative study of the antigenic specificities confirms that the Neq2 neuraminidases are closely connected, whatever their animal origin, and that the fowl strain Hav7 Neq2 can be used for the titration of anti Neq2 antibodies in the serums of animals immunized with the equine virus Heq2 Neq2. The Neqi neuraminidases of v...
[Effect of tranquilizer doping on the muscular activity of the sport horse. II. — Diazepam (author’s transl)]. The practise of repeated doping of the sport horse led us to examine its effects on the health of the animal, and particularly on muscular activity. The main doping agent used at present (acepromazine) has already been studied (COURTOT et al., 1974). In this paper, we study the secondary effects of diazepam, a derivative of the benzodiazepine series, which is being used more and more frequently on horses. In treated animals as compared to controls, we observe: -- a slight respiratory depression related solely to effort, -- an increase in seric creatine phosphokinase rate with no apparent relat...
[Effect of tranquilizer doping on the muscular activity on the sport horse. I. — Acepromazine (author’s transl)]. Doping with tranquilizers has appeared recently in horse-back riding sports. In this paper we study the effects of acepromazine, one of the main tranquilizers used, on various physiological and biochemical aspects of muscular activity (cardiac and respiratory rhythms, seric rates of glucose, urea, protein, creatine phosphokinase, glutamate oxalacetate transaminase, alkaline phosphatase). A low dose (0.02 mg/kg) of acepromazine is injected; the evolution of the variables is studied before and after a standardized effort. After the effort and during recuperation, acepromazine administration caus...
[Contribution to the antigenic study of influenza viruses in animals. II.–Antibodies, antineuraminidase in horse: conditions of apparition and importance (author’s transl)]. In the first part of this paper the conditions for a specific titration of antibodies against the neuraminidase (N) of each of the two horse virus subtypes are defined. The antigens used are: the H72Neq 1 recombining agent to measure the anti Neq1 antibodies and the A/Duck/Ukraine/63 strain for the anti Neq2 antibodies. The immunity response to neuraminidase appears after the natural disease; this response is studied in two foci, one due to a virus belonging to the A equi I subtype (Loire 73 strain), the other to a virus of the A equi 2 subtype (SHN 73 strain). The kinetics of apparition of an...