Blister Beetle Poisoning (Cantharidin Toxicity) in Horses: Causes, Treatment & Prevention
Blister beetles, also known as oil beetles, secrete a blistering agent called cantharidin as a natural defense against predators. Beetles in this family feed on flower blossoms, particularly in alfalfa plants, which makes them a common contaminant in alfalfa hay. Cantharidin is highly toxic to horses: ingestion of as little as five grams of beetles is enough to cause death in a 1 000 lb (540 kg) horse. Cantharidin toxicosis, also referred to as blister beetle poisoning, occurs when horses ingest a toxic dose of blister beetles.
