Omeprazole is a cornerstone of managing gastric ulcers in horses, working to reduce stomach acid and promote healing. Equine Gastric Ulcer Syndrome (EGUS) is extremely common, particularly in performance horses exposed to intensive training, travel, and dietary challenges. In equine...

Fluoxetine, commonly known by the trade name Prozac®, is a medication increasingly discussed in equine practice as an option for managing behavioral challenges in horses. As a selective serotonin reuptake inhibitor (SSRI), it works by increasing serotonin levels in the...

Hydroxyzine, sold under the brand name Vistaril®, is a first-generation antihistamine used in horses to reduce itching and inflammation caused by environmental and insect allergens. Unlike newer antihistamines, it crosses the blood–brain barrier, which means it can also cause drowsiness...

Domperidone, sold under the trade name Equidone® Gel, is a medication used in horses to support hormone balance and digestive function. It works by blocking dopamine, a neurotransmitter that supresses certain hormones, including prolactin. In equine practice, domperidone is most commonly...

Dexamethasone is a widely used corticosteroid in equine medicine, valued for its anti-inflammatory and immunosuppressive properties. Dexamethasone works by dampening the body's inflammatory response, providing rapid relief of clinical signs and improving overall comfort and function. Because of its strength...

Ketamine is a widely used medication in equine veterinary medicine, best known for its role as a fast-acting anesthetic. It is commonly administered during surgical procedures, diagnostic imaging, and emergency interventions, where it helps induce and maintain anesthesia while preserving...

Trimethoprim sulfadiazine, brand name Equisul-SDT®, is a combination antibiotic widely used in equine medicine for the treatment of bacterial infections. This medication combines two antimicrobial drugs that work together to stop bacteria from growing and multiplying, making it effective against...

Cetirizine, marketed in human medicine under the trade names Zyrtec® and Reactine®, is an antihistamine commonly used in human and small animal medicine. While there is interest in equine applications of antihistamine use, the effects of cetirizine in horses are...

Butylscopolamine, also Buscopan®, is a medication commonly used in horses to provide rapid relief from abdominal pain associated with spasmodic colic. As an antispasmodic agent, it works by relaxing smooth muscle in the gastrointestinal tract, helping reduce intestinal contractions that...

Cisapride is a prokinetic medication used in horses to stimulate movement in the gastrointestinal tract, helping restore normal gut motility when digestion slows or stops. It is most commonly used in cases of postoperative ileus, severe gastrointestinal hypomotility, or other...

Methocarbamol is a centrally acting muscle relaxant commonly used in horses to treat skeletal muscle spasms. These spasms can occur during conditions that cause muscle inflammation or injury and are often associated with disorders such as exertional rhabdomyolysis, commonly known...

Dantrolene is a skeletal muscle relaxant used in horses to manage conditions involving excessive skeletal muscle contraction or muscle damage, most notably exertional rhabdomyolysis (tying-up). Exertional rhabdomyolysis occurs when muscle cells become damaged during or after exercise, leading to pain,...

Clenbuterol is a bronchodilator used in horses for the management of lower airway disease, including equine asthma and other conditions associated with bronchoconstriction. These disorders occur when the small airways narrow due to inflammation, excess mucus, and smooth muscle contraction,...

Quinidine is an antiarrhythmic medication used in horses for the treatment of atrial fibrillation (AF), the most common type of cardiac arrhythmia that warrants medical intervention. Atrial fibrillation occurs when the upper chambers of the heart (the atria) beat in...