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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Scapulohumeral osteoarthritis in 20 Shetland ponies, miniature horses and falabella ponies.
The Veterinary record    March 22, 2001   Volume 148, Issue 6 175-179 doi: 10.1136/vr.148.6.175
Clegg PD, Dyson SJ, Summerhays GE, Schramme MC.This paper describes the clinical and diagnostic features of 20 cases of scapulohumeral osteoarthritis in Shetland ponies, miniature horses and falabella ponies. The history and clinical signs were similar in all the cases Radiographically they all had consistent changes which consisted predominantly of articular osteophytes and periarticular enthesiophytes. Six of the cases had radiographic evidence of dysplasia of the scapulohumeral joint, although it was uncertain whether this was a primary or a secondary finding. No specific treatment appeared to be advantageous. At follow up, six of the p...
Evaluation of high-speed treadmill videoendoscopy for diagnosis of upper respiratory tract dysfunction in horses.
Australian veterinary journal    March 21, 2001   Volume 79, Issue 2 109-112 doi: 10.1111/j.1751-0813.2001.tb10713.x
Dart AJ, Dowling BA, Hodgson DR, Rose RJ.To evaluate high-speed treadmill videoendoscopy as a diagnostic technique and document the abnormalities found in Australian horses referred for poor performance associated with abnormal upper respiratory tract noise but where a definitive diagnosis could not be made at rest. Methods: A retrospective clinical study using client-owned horses. Methods: The clinical records and videorecordings of all horses referred to the University of Sydney for poor performance associated with abnormal upper respiratory tract noise during a 13-month period were examined. Only horses with a normal physical exam...
Ultrasound-spirometry and capnography in horses: analysis of measurement reliability.
Veterinary research communications    March 13, 2001   Volume 25, Issue 2 137-147 doi: 10.1023/a:1006409003122
Herholz C, Straub R, Busato A.Ultrasound-spirometry and capnography and the evaluation of corresponding 'single-breath diagrams for CO2' (SBD-CO2) is a relatively new, non-invasive method for assessing pulmonary function in horses. The relative variation and the reliability of observations within measurement sessions were calculated for expiratory tidal volume, for expired CO2 volume (%) and for the phase II and phase III slopes of the SBD-CO2 in horses without pulmonary disease and in horses suffering from differing degrees of chronic obstructive pulmonary disease. The coefficient of variation of expiratory tidal volume r...
Coughing in thoroughbred racehorses: risk factors and tracheal endoscopic and cytological findings.
The Veterinary record    March 10, 2001   Volume 148, Issue 4 99-104 doi: 10.1136/vr.148.4.99
Christley RM, Hodgson DR, Rose RJ, Hodgson JL, Wood JL, Reid SW.A matched case-control study was made of 100 thoroughbred horses which were coughing and 148 control horses which were free of clinical signs of respiratory tract disease. The variables identified by multivariable conditional logistic regression as being significantly associated with coughing included age (the risk decreased with age), the stage of training (horses in early training were at greatest risk), the time since the last race (horses that had never raced were at greatest risk) and the time since they were last transported (horses transported more than 14 days previously were more like...
Retrograde ejaculation in a stallion.
Journal of the American Veterinary Medical Association    March 7, 2001   Volume 218, Issue 4 551-527 doi: 10.2460/javma.2001.218.551
Brinsko SP.Retrograde ejaculation was diagnosed in a 10-year-old Arabian stallion. Despite behavioral signs consistent with ejaculation, the collection receptacle of an artificial vagina remained devoid of semen on numerous occasions. Catheterization of the urinary bladder yielded large numbers of spermatozoa, even when an ejaculate was obtained, whereas low numbers (< 1 X 10(6)/ml) of spermatozoa are found in the bladder of clinically normal stallions after ejaculation. Endoscopic examination of the urethra, seminal colliculus, and bladder failed to reveal abnormalities. Medical treatment with imipra...
Putative uremic encephalopathy in horses: five cases (1978-1998).
Journal of the American Veterinary Medical Association    March 7, 2001   Volume 218, Issue 4 560-566 doi: 10.2460/javma.2001.218.560
Frye MA, Johnson JS, Traub-Dargatz JL, Savage CJ, Fettman MJ, Gould DH.To determine historical, physical examination, clinicopathologic, and postmortem findings in horses with putative uremic encephalopathy. Design-Retrospective study. Animals-5 horses with renal failure and neurologic disease not attributable to abnormalities in any other organ system. Methods: Medical records from 1978 to 1998 were examined for horses with renal disease and neurologic signs not attributable to primary neurologic, hepatic, or other diseases. Signalment, history, physical examination findings, clinicopathologic data, renal ultrasonographic findings, and postmortem data were revie...
Clinical experiences with axial deviation of the aryepiglottic folds in 52 racehorses.
Veterinary surgery : VS    March 7, 2001   Volume 30, Issue 2 151-160 doi: 10.1053/jvet.2001.21389
King DS, Tulleners E, Martin BB, Parente EJ, Boston R.To describe the clinical findings in 52 racehorses with axial deviation of the aryepiglottic folds (ADAF) and to report outcome in 33 of these horses after either rest or transendoscopic laser excision of aryepiglottic fold tissue. Methods: Retrospective study. Methods: Racehorses admitted for high-speed treadmill (HST) evaluation of poor performance. Methods: Medical records and videotapes of resting and exercising videoendoscopic examinations were reviewed. Racing performance records and owner or trainer interviews, at least 1 year after HST examination, were used to compare results after ei...
[Case report: (erythro)keratoderma variabilis in a newborn foal].
Berliner und Munchener tierarztliche Wochenschrift    February 28, 2001   Volume 114, Issue 1-2 40-43 
Wehrend A, Meyer W, Herfen K, Bostedt H.A case of congenital (Erythro)keratoderma variabilis in a newborn foal is described. The clinical and histological findings are presented.
Pituitary-independent Cushing’s syndrome in a horse.
Equine veterinary journal    February 24, 2001   Volume 33, Issue 1 110-112 doi: 10.2746/042516401776767368
van der Kolk JH, Ijzer J, Overgaauw PA, van der Linde-Sipman JS.No abstract available
Clinical vignette. Von Willebrand disease in a Thoroughbred mare and foal.
Journal of veterinary internal medicine    February 24, 2001   Volume 15, Issue 1 63-66 doi: 10.1111/j.1939-1676.2001.tb02302.x
Rathgeber RA, Brooks MB, Bain FT, Byars TD.No abstract available
Risk factors for reduced postoperative fecal output in horses: 37 cases (1997-1998).
Journal of the American Veterinary Medical Association    February 24, 2001   Volume 218, Issue 3 414-420 doi: 10.2460/javma.2001.218.414
Little D, Redding WR, Blikslager AT.To determine prevalence and risk factors for development of ileus of the large intestine after surgery in horses, identified by reduced postoperative fecal output (RPFO). Methods: Retrospective study. Methods: 37 horses that developed RPFO after undergoing general anesthesia for reasons unrelated to the gastrointestinal tract. Methods: Fecal output was obtained from medical records as number of defecations per 24-hour period after surgery; RPFO was defined as < or = 3 defecations per 24-hour period after surgery. The reference population included 48 horses that defecated > or = 4 times during ...
Putting theory into practice.
Equine veterinary journal. Supplement    February 24, 2001   Issue 32 6-7 doi: 10.1111/j.2042-3306.2000.tb05326.x
Proudman CJ.No abstract available
Equine basal cell tumors: 6 cases (1985-1999).
Journal of veterinary internal medicine    February 24, 2001   Volume 15, Issue 1 43-46 doi: 10.1892/0891-6640(2001)0152.3.co;2
Slovis NM, McEntee MC, Fairley RA, Galuppo LD, Théon AP.Basal cell tumors are rare benign tumors in horses. Over a 15-year period, 6 horses were diagnosed with basal cell tumors. The tumors were well-circumscribed. freely moveable, firm, raised papules, nodules, or masses that ranged from 0.6 to 5 cm in diameter. Five of the 6 tumors were ulcerated. Based on gross appearance, the tumors were diagnosed as sarcoids, and 1 was diagnosed as a melanoma. The range of age of affected horses was 6-26 years. The tumors were identified clinically 1 week to 3 years before excision. In 4 horses for which information was available, complete surgical excision wa...
Fistulation of the auditory tube diverticulum (guttural pouch) with a neodymium:yttrium-aluminum-garnet laser for treatment of chronic empyema in two horses.
Journal of the American Veterinary Medical Association    February 24, 2001   Volume 218, Issue 3 405-361 doi: 10.2460/javma.2001.218.405
Hawkins JF, Frank N, Sojka JE, Levy M.Two horses with chronic empyema of the auditory tube diverticulum (guttural pouch) were refractory to medical treatment; empyema was bilateral in 1 horse and unilateral in the other. Both horses were treated by fistulation of the cartilage of the pharyngeal orifice by use of a neodymium:yttrium-aluminum-garnet laser in a noncontact manner. To maintain patency of the fistulae, indwelling catheters were placed into the openings created by the laser. For both horses, long-term follow-up did not reveal complications, and both owners were satisfied with results of the procedure. The authors recomme...
International Workshop on Equine Chronic Airway Disease. Michigan State University 16-18 June 2000.
Equine veterinary journal    February 24, 2001   Volume 33, Issue 1 5-19 doi: 10.2746/042516401776767412
Robinson NE.No abstract available
Diagnosis of eastern equine encephalitis by immunohistochemistry in two flocks of Michigan ring-neck pheasants.
Avian diseases    February 24, 2001   Volume 44, Issue 4 1012-1016 
Williams SM, Fulton RM, Patterson JS, Reed WM.The diagnosis of eastern equine encephalitis (EEE) virus infection in avian species is relatively difficult when compared with other species. There are no characteristic histologic lesions in the avian brain that would serve to distinguish EEE from infections with, for example, Newcastle disease or highly pathogenic avian influenza virus. Traditionally, virus isolation (VI) and/or hemagglutination inhibition (HI) has been used for a definitive diagnosis of EEE in birds. Recently, we developed an immunohistochemistry (IHC) technique for confirmatory diagnosis of EEE infection in equine brain. T...
Incidence of the endothelin receptor B mutation that causes lethal white foal syndrome in white-patterned horses.
American journal of veterinary research    February 24, 2001   Volume 62, Issue 1 97-103 doi: 10.2460/ajvr.2001.62.97
Santschi EM, Vrotsos PD, Purdy AK, Mickelson JR.To determine incidence of the Ile118Lys endothelin receptor B (EDNRB) mutation responsible for overo lethal white syndrome (OLWS) and its association with specific types of white patterning. Methods: 945 horses of white-patterned bloodlines and 55 solid-colored horses of other breeds. Methods: Horses were genotyped by use of allele-specific polymerase chain reaction to determine incidence of the Ile118Lys EDNRB mutation. Results: Genotypes detected were homozygous Ile118, homozygous Lys118, and heterozygous. All foals with OLWS were homozygous for the Ile118Lys EDNRB mutation, and adults that ...
Celiotomy closure via permanent implantation of polyamide in horses.
Equine veterinary journal. Supplement    February 24, 2001   Issue 32 101-103 doi: 10.1111/j.2042-3306.2000.tb05344.x
Beroza GA, Perry RW, Cotter DM.Permanent implantation of nonabsorbable materials is appropriate in many surgical circumstances but is not commonly used to close equine celiotomies. This paper describes a simple method of continuous nonabsorbable implantation of polyamide suture used successfully to close 48 equine celiotomies. Forty-eight clean or clean-contaminated celiotomies were successfully performed over 5 years using this technique. The postsurgical survival observation period ranged from 1-6 years (median 3.5 years). There were 45 long-term survivors (93.75%). Only 2 minor implant complications (4.4%) were observed ...
Cushing’s disease: a new approach to therapy in equine and canine patients.
The British homoeopathic journal    February 24, 2001   Volume 90, Issue 1 33-36 doi: 10.1054/homp.1999.0450
Elliott M.Forty-one cases of Cushing's Disease affecting both equine and canine patients were treated with an identical mixture of two homeopathically prepared remedies (ACTH 30c and Quercus robur 30c), and the clinical improvements seen in the cases assessed. Homeopathy has been described as a medicine that can only be prescribed on the basis of individual symptoms shown, fitting the remedy to the patient, not the disease. The aim of this study was to define whether a standardised approach, using homeopathically prepared remedies, was a valid system of therapy for this disease, and if so, whether resul...
Intermittent hypoglycemia in a horse with anaplastic carcinoma of the kidney.
Journal of the American Veterinary Medical Association    February 24, 2001   Volume 218, Issue 2 235-237 doi: 10.2460/javma.2001.218.235
Baker JL, Aleman M, Madigan J.Clinically apparent hypoglycemia is rare in adult horses. Hypoglycemia is a well-recognized paraneoplastic syndrome in humans and dogs with non-insulin-secreting tumors and may occur in horses as well. Hypoglycemia associated with non-insulin-secreting tumors is believed to result from production of an abnormal form of insulin-like growth factor II. Neoplasia should be considered in the differential diagnosis for adult horses with hypoglycemia.
Diagnosis and treatment of chronic recurrent caecal impaction.
Equine veterinary journal. Supplement    February 24, 2001   Issue 32 65-68 doi: 10.1111/j.2042-3306.2000.tb05336.x
Huskamp B, Scheidemann W.Ninety-six horses with chronic recurrent caecal impaction associated with hypertrophy of muscle layers in the caecal base or in the whole caecum were examined from 1990 to 1996. Enlargement of the caecocolic orifice was completed surgically in 58 horses. Of those horses having surgery, 50 were discharged from the hospital while 8 were subjected to euthanasia at the hospital due to complications. Twenty-seven of the 50 horses discharged were normal at follow-up while 23 died or were subjected to euthanasia due to acute or recurrent colic, recurrent impaction in the ascending or descending colon...
Effect of oral administration of excessive iron in adult ponies.
Journal of the American Veterinary Medical Association    February 24, 2001   Volume 218, Issue 3 400-404 doi: 10.2460/javma.2001.218.400
Pearson EG, Andreasen CB.To evaluate the potential of excess dietary iron to cause hepatic lesions similar to those described in horses with suspected iron toxicosis or hemochromatosis. Methods: Prospective study. Methods: 6 adult male ponies. Methods: 4 ponies received 50 mg of iron/kg (22.7 mg/lb) of body weight each day by oral administration of ferrous sulfate, which contained 20% elemental iron; 2 ponies received only the carrier (applesauce). Complete blood counts, serum biochemical analyses, and hepatic tissue biopsies were performed, and serum iron concentrations were measured. Blood and tissue samples were ob...
Design and clinical use of a modified colon tray for large colon evacuation in the horse.
Equine veterinary journal. Supplement    February 24, 2001   Issue 32 81-85 doi: 10.1111/j.2042-3306.2000.tb05340.x
Mariën T, Adriaenssen A, Segers L.A modified colon tray to perform large colon evacuations in horses was designed. A funnel-shaped accessory was constructed to create a mechanical separation between the sterile and nonsterile part of the tray. Sterile hooks were used to make a temporary and stabile colostomy. Thirty horses with surgical correction of nonstrangulating large colon obstruction underwent a large colon evacuation with this modified tray. The surgical procedure was uncomplicated and resulted in a positive outcome in 29 horses. This less labour-intensive way to evacuate the large colon results in minor contamination ...
Emergent causes of placentitis and abortion.
The Veterinary clinics of North America. Equine practice    February 24, 2001   Volume 16, Issue 3 443-viii doi: 10.1016/s0749-0739(17)30088-3
Donahue JM, Williams NM.The clinical signs, laboratory findings, diagnosis, epidemiology, treatment, and prevention and control of two emerging causes of placentitis and abortion in horses are described in this article. Leptospirosis has been reported as a significant cause of fetal loss in horses in Kentucky, Northern Ireland, and England. Most abortions result from infection by serovars kennewicki or bratislava. Nocardioform placentitis has become the most common cause of placentitis in central Kentucky horses. Nocardioform placentitis is associated with infection by unnamed, gram-positive, filamentous, branching b...
Short- and long-term survival and prevalence of postoperative ileus after small intestinal surgery in the horse.
Equine veterinary journal. Supplement    February 24, 2001   Issue 32 42-51 doi: 10.1111/j.2042-3306.2000.tb05333.x
Freeman DE, Hammock P, Baker GJ, Goetz T, Foreman JH, Schaeffer DJ, Richter RA, Inoue O, Magid JH.The records of 74 horses that recovered from anaesthesia after surgery for a small intestinal lesion from 1994 to 1999 were reviewed. Sixty-three horses (85%) had a strangulating lesion and 43 of these (68%) had a resection and anastomosis. Four of 11 horses (36%) without a strangulating lesion had a resection and anastomosis. Sixty-three horses (85%) survived to discharge, with a survival rate of 53/63 in horses with a strangulating lesion (84%) and 10/11 (91%) in others. For all lesions, short-term survival for all end-to-end anastomoses (91%; 21/23) and for no resection (92%; 23/25) were su...
Equine lymphocytic-plasmacytic enterocolitis: a retrospective study of 14 cases.
Equine veterinary journal. Supplement    February 24, 2001   Issue 32 108-112 doi: 10.1111/j.2042-3306.2000.tb05346.x
Kemper DL, Perkins GA, Schumacher J, Edwards JF, Valentine BA, Divers TJ, Cohen ND.Lymphocytic-plasmacytic enteritis (LPE) is a morphological diagnosis given to a type of infiltrative intestinal disease classified within the complex of idiopathic inflammatory bowel disease (IBD). The purpose of this retrospective study was to describe the details of breed, age and sex, clinical and clinicopathological findings and outcome of horses diagnosed with LPE. Data were reported from 14 horses that had a histopathological diagnosis of LPE; the median age was 12 years, and there was no breed or sex predilection. Common clinical signs were weight loss (100%), diarrhoea (50%) and lethar...
Effect of extensive ileal resection with a large resulting mesenteric defect and stapled ileal stump in horses with a jejunocaecostomy: a comparison with other anastomotic techniques.
Equine veterinary journal. Supplement    February 24, 2001   Issue 32 52-58 doi: 10.1111/j.2042-3306.2000.tb05334.x
Bladon BM, Hillyer MH.Extensive resection of the ileum of the horse, using automated stapling equipment followed by a stapled jejunocaecostomy, without closure of the mesenteric defect, was evaluated prospectively as a surgical treatment for lesions involving the distal small intestine. Of 153 horses treated surgically for colic, 10 horses with strangulating lesions involving the distal ileum were treated by extensive resection and jejunocaecal anastomosis leaving a residual mesenteric defect. These were compared with 12 horses with jejunoileal lesions treated by jejunocaecal anastomosis with closure of the mesente...
Hypercoagulation and hypofibrinolysis in horses with colic and DIC.
Equine veterinary journal. Supplement    February 24, 2001   Issue 32 19-25 doi: 10.1111/j.2042-3306.2000.tb05329.x
Monreal L, Anglés A, Espada Y, Monasterio J, Monreal M.Changes in haemostasis in horses with colic were assessed by using specific and sensitive markers of coagulation and fibrinolysis activity. Blood samples from 41 horses with severe colic and from 30 healthy control horses were tested. Diagnosis of DIC was based on the findings of at least 3 of 6 abnormalities: thrombocytopenia, prolonged clotting times (PT and APTT), increased polyclonal FDPs, decreased fibrinogen and decreased AT-III activity. Plasma thrombin-antithrombin III complexes (TAT), monoclonal fibrin degradation products fragment D (D-dimer) and monoclonal fibrinogen degradation pro...
Nephrosplenic entrapment in the horse: a retrospective study of 174 cases.
Equine veterinary journal. Supplement    February 24, 2001   Issue 32 95-97 doi: 10.1111/j.2042-3306.2000.tb05342.x
Hardy J, Minton M, Robertson JT, Beard WL, Beard LA.The clinical findings and outcome of 161 horses diagnosed with 174 episodes of nephrosplenic entrapment (NSE) were reviewed retrospectively. The median age at presentation was 5 years (9 months to 24 years), and duration of colic was 2-92 h. Nasogastric reflux was present in 49 of 113 horses (43.4%) and was significant (> or = 21) in 32 (28.3%) horses. The recurrence rate was 13/161 (8.1%). Thirteen horses (13/174, 7.5%) had other lesions including small intestinal obstruction (4), 360 degrees large colon torsion (5), gastric rupture (2), thromboembolic colic (1) and small colon infarction (1)...
Prevalence and prognostic importance of hypomagnesemia and hypocalcemia in horses that have colic surgery.
American journal of veterinary research    February 24, 2001   Volume 62, Issue 1 7-12 doi: 10.2460/ajvr.2001.62.7
Garcia-Lopez JM, Provost PJ, Rush JE, Zicker SC, Burmaster H, Freeman LM.To determine the prevalence of hypomagnesemia and hypocalcemia in horses with surgical colic. Methods: 35 horses with surgically managed colic. Methods: Serum concentrations of total magnesium (tMg2+) and calcium (tCa2+), as well as ionized magnesium (iMg2+) and calcium (iCa2+) were analyzed before surgery and 1, 3, 5, and 7 days following surgery. A lead-II ECG and pertinent clinical data were also obtained at each time. Results: Preoperative serum tMg2+ and iMg2+ concentrations were below the reference range in 6 (17%) and 19 (54%) horses, respectively. Serum concentrations of tCa2+ and iCa2...