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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Equine idiopathic cheek teeth fractures: part 3: a hospital-based survey of 68 referred horses (1999-2005).
Equine veterinary journal    August 29, 2007   Volume 39, Issue 4 327-332 doi: 10.2746/042516407x182983
Dixon PM, Barakzai SZ, Collins NM, Yates J.There is limited information available on the more serious sequellae of idiopathic cheek teeth (CT) fractures. Objective: To obtain information on clinical and ancillary diagnostic findings in referred horses with idiopathic CT fractures. Methods: Details of all horses suffering from idiopathic CT fractures referred to the Equine Hospital at the University of Edinburgh 1999-2005 were examined, and information concerning fracture patterns, clinical and ancillary diagnostic findings, treatments and long-term response to treatments were obtained and analysed. Results: A total of 60 maxillary and ...
Culicoides species attracted to horses with and without insect hypersensitivity.
Veterinary journal (London, England : 1997)    August 28, 2007   Volume 178, Issue 1 91-97 doi: 10.1016/j.tvjl.2007.07.005
van der Rijt R, van den Boom R, Jongema Y, van Oldruitenborgh-Oosterbaan MM.The aims of this study were to determine (1) which species of Culicoides is most commonly attracted to horses, (2) whether horses suffering insect hypersensitivity attract more Culicoides spp. than unaffected horses, and (3) the times when Culicoides spp. are most active. Horses affected by insect hypersensitivity and unaffected horses were placed inside mosquito netting tents for 30 min at different times of the day. All Culicoides spp. trapped inside the tents were collected and identified. C. obsoletus was the most common species found, followed by C. pulicaris. Healthy horses attracted sli...
Confirmed and presumptive cervical vertebral compressive myelopathy in older horses: a retrospective study (1992-2004).
Journal of veterinary internal medicine    August 22, 2007   Volume 21, Issue 4 812-819 doi: 10.1892/0891-6640(2007)21[812:capcvc]2.0.co;2
Levine JM, Adam E, MacKay RJ, Walker MA, Frederick JD, Cohen ND.Cervical vertebral compressive myelopathy (CVCM) is a common cause of myelopathy in horses aged 6 months to 4 years. Little information is available regarding the types of lesions, treatment, and outcomes in horses with CVCM that are > or =4 years old. Methods: Twenty-two affected horses (10 with a confirmed diagnosis of CVCM and 12 presumptive cases) and 210 contemporaneous control horses. Methods: Horses > or =4 years old that were diagnosed with CVCM between January 1992 and January 2004 were identified from medical records at Texas A&M University and the University of Florida. Data analyze...
Treatment in the field of 27 horses with epiglottic entrapment.
The Veterinary record    August 19, 2007   Volume 161, Issue 6 187-189 doi: 10.1136/vr.161.6.187
Russell T, Wainscott M.Twenty-seven horses were treated for epiglottic entrapment by using an oral, hand-assisted bistoury knife technique, under general anaesthesia; 26 of them returned successfully to racing, but one developed a permanently displaced soft palate. After the surgery 13 of the horses had an increased handicap rating and 13 had a decreased rating.
Effect of butorphanol administration on cardiovascular parameters in isoflurane-anesthetized horses – a retrospective clinical evaluation.
Veterinary anaesthesia and analgesia    August 13, 2007   Volume 35, Issue 1 38-44 doi: 10.1111/j.1467-2995.2007.00355.x
Hofmeister EH, Mackey EB, Trim CM.To determine cardiovascular responses to administration of butorphanol in isoflurane-anesthetized horses. Methods: Retrospective evaluation of anesthetic records. Methods: Seventy-six horses anesthetized for a variety of clinical surgical procedures. Methods: Anesthetic records of clinical equine patients anesthetized between January 1999 and December 2003 were searched. The records were reviewed for horses in which anesthesia was induced with ketamine and a benzodiazepine and maintained with isoflurane, and horses that received butorphanol intraoperatively. Exclusion criteria included horses ...
Papillary renal adenoma of distal nephron differentiation in a horse.
The Journal of veterinary medical science    August 7, 2007   Volume 69, Issue 7 763-765 doi: 10.1292/jvms.69.763
Matsuda K, Kousaka Y, Nagamine N, Tsunoda N, Taniyama H.A 20-year-old thoroughbred mare had a mass in the right kidney. The mass was encapsulated with fibrous capsule and composed of variably-sized papillary projections lined by a single layer of flattened to cuboidal neoplastic epithelial cells with no cytological and nuclear atypia. Immunohistochemically, the neoplastic cells were broadly positive for cytokeratin AE1/AE3 and granular staining for alpha-1-antitrypsin was focally detected; this immunohistochemical property was similar to that of the normal distal nephron. From these results, this case was diagnosed as papillary renal adenoma of dis...
Validation of computerized Swedish horse insurance data against veterinary clinical records.
Preventive veterinary medicine    July 17, 2007   Volume 82, Issue 3-4 236-251 doi: 10.1016/j.prevetmed.2007.05.020
Penell JC, Egenvall A, Bonnett BN, Pringle J.The aim was to evaluate the agreement between computerized insurance data in a large Swedish horse insurance database and the information in the corresponding clinical records (CR). A random sample of 400 veterinary care and 140 life claims was included. Information on name of the horse, breed and gender, year of birth, specific diagnosis and system diagnosis (e.g. joints, digestive and skeletal) was compared between sources. The concordance for demographic variables was categorized as agreement, disagreement or data missing. For diagnostic information, the categories were agreement, minor dis...
Clinical and clinicopathologic variables in adult horses receiving blood transfusions: 31 cases (1999-2005).
Journal of the American Veterinary Medical Association    July 17, 2007   Volume 231, Issue 2 267-274 doi: 10.2460/javma.231.2.267
Hurcombe SD, Mudge MC, Hinchcliff KW.To determine clinical and clinicopathologic abnormalities in horses administered a blood transfusion and evaluate effects of blood transfusion on these variables. Methods: Retrospective case series. Methods: 31 adult horses that received > or = 1 blood transfusion. Procedures-Medical records of horses receiving a blood transfusion were reviewed to obtain clinical findings, laboratory test results before and after transfusion, adjunctive treatments, transfusion type and volume, response to transfusion, results of donor-recipient compatibility testing, adverse reactions, and outcome. Results:...
Comparison of three dorsal techniques for arthrocentesis of the distal interphalangeal joint in horses.
Journal of the American Veterinary Medical Association    July 17, 2007   Volume 231, Issue 2 254-258 doi: 10.2460/javma.231.2.254
Gandini M.To compare 3 dorsal techniques for arthrocentesis of the distal interphalangeal joint in horses with regard to ease of performing the technique and to determine the role of operator experience in ease of performing these techniques. Methods: Observational study. Sample Population-Forelimbs from 17 equine cadavers and 12 horses (16 joints) undergoing arthrocentesis for therapeutic or diagnostic purposes. Methods: In both forelimbs from 7 of the equine cadavers, 3 arthrocentesis techniques (dorsal perpendicular, dorsolateral, and dorsal inclined) were performed in random order by a single experi...
[Saddle pressure measurements at the horse. Validity, repeatability and the ability to distinguish different seed fragments].
Tijdschrift voor diergeneeskunde    July 11, 2007   Volume 132, Issue 11 436-437 
de Cocq P.No abstract available
Evidence-based medicine in equine critical care.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 293-316 doi: 10.1016/j.cveq.2007.04.001
Bedenice D.One of the fundamental skills required for practicing evidence-based medicine is the development of a well-built clinical question, which specifies the patient group or problem, intervention, and outcome of interest. For this purpose, various "levels of evidence" have been developed in the human literature, which rank the validity of evidence. Our established conclusions and advice are thus supported by specific "grades of recommendations," which are intended to give an indication of the "strength" of a clinical recommendation. This article was compiled with these principles in mind.
Evidence-based literature pertaining to thyroid dysfunction and Cushing’s syndrome in the horse.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 329-364 doi: 10.1016/j.cveq.2007.04.004
Messer NT, Johnson PJ.The evidence-based literature pertaining to thyroid dysfunction and Cushing's syndrome is discussed in this article. Summaries of and recommendations for the treatment of these conditions are made. There is a need for reliable diagnostic tests for these conditions in horses.
Common procedures in broodmare practice: what is the evidence?
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 385-402 doi: 10.1016/j.cveq.2007.03.003
Brinsko SP.Many procedures performed as part of routine broodmare practice are based on sound clinical judgment and experience or scientific evidence; however, others are based on perceived problems and needs to address them. This article presents four procedures commonly used in broodmare practice, for which there is questionable evidence to substantiate their use.
Evidence-based lameness detection and quantification.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 403-423 doi: 10.1016/j.cveq.2007.04.008
Keegan KG.Kinematic and kinetic gait analysis potentially offers veterinarians an objective method of determining equine limb lameness. Subjective analyses have been shown to be somewhat flawed, and there does not seem to be a high degree of intraobserver agreement when evaluating individual horses. In addition, recognition of the compensatory effects of primary lameness may be helpful for the practicing equine veterinarian.
Evidence-based parasitology in horses.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 509-517 doi: 10.1016/j.cveq.2007.04.009
Uhlinger CA.This article focuses on what has been established concerning the interaction of equine parasites and their hosts, highlighting those issues for which convincing data are still lacking. There is a compelling need for the participation of the veterinarian in the design of appropriate anthelmintic treatments and prevention strategies.
Tri-level surgical treatment of cervical spinal cord compression in a Thoroughbred yearling.
The Canadian veterinary journal = La revue veterinaire canadienne    July 10, 2007   Volume 48, Issue 6 635-638 
Huggons N.A Thoroughbred yearling was presented with neurological, radiographic, and myelographic abnormalities consistent with cervical vertebral stenotic myelopathy. Surgical correction was performed by using ventral cervical interbody fusion at 3 intervertebral spaces. The patient recovered uneventfully from surgery. The neurological status remained unchanged initially; however, significant improvement was noted 37 weeks postoperatively. Un Thoroughbred d’un an a été présenté avec des anomalies neurologiques, radiographiques et myélographiques compatibles avec une myélopathie sténosée des ...
An evidence-based approach to clinical questions in the practice of equine neurology.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 317-328 doi: 10.1016/j.cveq.2007.03.009
Van Biervliet J.The practice of equine neurology has special challenges posed by the size of the animal being examined. Many diagnostic procedures routinely used in small animal practice are unsafe when applied to the equine patient or unavailable to the equine practitioner. Therefore, astute observation is the mainstay of making a neuroanatomic diagnosis, and detailed evidence on the deficits present may be difficult to obtain. Because clinical observation can sometimes be ambiguous and somewhat subjective, it is even more important to approach equine neurology from an evidence-based point of view. Here, suc...
Effects of intra-articular botulinum toxin type A in an equine model of acute synovitis: a pilot study.
American journal of physical medicine & rehabilitation    July 5, 2007   Volume 86, Issue 10 777-783 doi: 10.1097/PHM.0b013e3181157718
DePuy T, Howard R, Keegan K, Wilson D, Kramer J, Cook JL, Childers MK.To test the hypothesis that botulinum toxin type A (BoNT-A) can attenuate lameness associated with acute synovitis in an equine model. Methods: Four horses 2-6 yrs of age with clinically normal carpi were studied for 15 days. Kinematic gait analysis and clinical measures of lameness were conducted before and after experimental interventions. Horses were randomly assigned to either placebo (saline) or treatment (BoNT-A) groups. On day 0 of the intervention, 50 units of BoNT-A or an equivalent volume of saline (0.09%) was given into the middle carpal joints. On day 14, acute synovitis was induce...
Effect of adjunctive treatment with intravenously administered Propionibacterium acnes on reproductive performance in mares with persistent endometritis.
Journal of the American Veterinary Medical Association    July 4, 2007   Volume 231, Issue 1 107-113 doi: 10.2460/javma.231.1.107
Rohrbach BW, Sheerin PC, Cantrell CK, Matthews PM, Steiner JV, Dodds LE.To determine whether treatment with a preparation of Propionibacterium acnes would improve pregnancy and live foal rates in mares with persistent endometritis. Methods: Randomized placebo-controlled clinical trial. Methods: 95 mares with a cytologic diagnosis of persistent endometritis. Methods: Mares were treated with P acnes or placebo (both administered IV) on days 0, 2, and 6. No attempt was made to alter additional treatments administered by attending veterinarians. Information on breeding history, physical examination findings, results of cytologic examination and microbial culture of ut...
Salinomycin toxicosis in horses.
Journal of the American Veterinary Medical Association    June 19, 2007   Volume 230, Issue 12 1822-1826 doi: 10.2460/javma.230.12.1822
Aleman M, Magdesian KG, Peterson TS, Galey FD.A 4-month-old American Paint filly was evaluated because of sudden onset of ataxia that progressed to recumbency. Five additional horses from the same and neighboring premises developed signs of poor performance, generalized weakness, ataxia, and recumbency; 2 of those horses were also evaluated. A new batch of a commercial feed supplement had been introduced to the horses' diet on each farm within the preceding 3 days. Results: Other than recumbency, findings of physical and neurologic examinations of the foal were unremarkable. The other 2 horses had generalized weakness and mild ataxia, and...
Exposure of veterinary personnel to ionising radiation during bone scanning of horses by nuclear scintigraphy with 99mtechnetium methylene diphosphonate.
The Veterinary record    June 19, 2007   Volume 160, Issue 24 832-835 doi: 10.1136/vr.160.24.832
Gatherer ME, Faulkner J, Voûte LC.The aim of this study was to compare the radiation doses received by the personnel drawing up and injecting the radiopharmaceutical and operating the nuclear scintigraphy equipment, and those restraining nine horses while they were being scanned during scintigraphic investigations of lameness. Sensitive electronic dosimeters were worn by the personnel and the doses they received during the administration of the radiopharmaceutical and during the period of image acquisition were recorded at intervals. On average, 90 per cent of the total doses were received during the period of image acquisitio...
Comparison of ketamine and S(+)-ketamine, with romifidine and diazepam, for total intravenous anesthesia in horses.
Veterinary anaesthesia and analgesia    June 12, 2007   Volume 35, Issue 1 30-37 doi: 10.1111/j.1467-2995.2007.00351.x
Rossetti RB, Gaido Cortopassi SR, Intelizano T, de Lima Machado TS, Ferreira da Cruz RS.To compare the quality of induction and recovery, degree of muscle relaxation, clinically apparent potency and cardiopulmonary effects of racemic ketamine or S(+)-ketamine when used for total intravenous anesthesia in horses. Methods: Prospective randomized clinical trial Methods: Sixteen healthy stallions (323 +/- 99 kg), with a mean age of 6.2 years, undergoing castration. Methods: Horses were pre-medicated with romifidine IV, 15 minutes before induction of anesthesia. Each animal was then randomly allocated to receive either diazepam and ketamine (DK) or diazepam and S(+)-ketamine (DKS) at ...
Effects of syringe type and storage temperature on results of blood gas analysis in arterial blood of horses.
Journal of veterinary internal medicine    June 8, 2007   Volume 21, Issue 3 476-481 doi: 10.1892/0891-6640(2007)21[476:eostas]2.0.co;2
Picandet V, Jeanneret S, Lavoie JP.Results of arterial blood gas analysis can be biased by pre-analytical factors, such as time to analysis, syringe type, and temperature during storage. However, the acceptable delay between time of collection and analysis for equine arterial blood gas remains unknown. Objective: Dedicated plastic syringes provide better stability of arterial blood gases than multipurpose plastic syringes. Methods: Eight mares, 1 stallion, and 1 gelding, ages 3 to 10 years old. Methods: Arterial blood samples were collected in a glass syringe, a plastic syringe designated for blood gas collection, and a multipu...
Thoracic percussion to determine the caudal lung border in healthy horses.
Journal of veterinary internal medicine    June 8, 2007   Volume 21, Issue 3 504-507 
Bakos Z, Vörös K.The application of equine thoracic percussion has been ignored because of the availability of modern imaging techniques. Ultrasonography is a reliable tool in determining the caudal lung border of horses. The aim of the study was to compare percussion with ultrasonography to determine lung borders in horses. Objective: That thoracic percussion can detect the caudal lung border and that its accuracy is comparable with thoracic ultrasonography. Methods: Fifteen randomly chosen, healthy, Warmblood horses. Methods: The caudal lung border was detected by percussion and ultrasonography at the end of...
Serum bile acids concentrations in healthy and clinically ill neonatal foals.
Journal of veterinary internal medicine    June 8, 2007   Volume 21, Issue 3 508-513 doi: 10.1892/0891-6640(2007)21[508:sbacih]2.0.co;2
Barton MH, LeRoy BE.Reference ranges for serum bile acids (SBA) concentration are well established in healthy adult horses. Increased values are indicative of hepatic disease. Objective: SBA concentrations are significantly greater in the neonatal period compared with mature horses, and illness in the neonatal period will further increase SBA. Methods: Ten healthy mature horses, 12 healthy foals, and 31 clinically ill foals. Methods: Prospective cross-sectional study. Blood samples were obtained once from the mature horses, from healthy foals immediately after birth, at 2 days, and at 1, 2, 3, 4, and 6 weeks of a...
Equine endometrial biopsy: enhancement of clinical value by more extensive histopathology and application of new diagnostic techniques?
Theriogenology    June 8, 2007   Volume 68, Issue 3 413-422 doi: 10.1016/j.theriogenology.2007.04.040
Schlafer DH.During the 1960s and 1970s, the clinical value of equine endometrial histopathology was firmly established after it was shown that fertility outcome was correlated with the presence and severity of specific microscopic lesions. The objective of this paper is to summarize reports from the veterinary literature published after the mid 1980s that describe new diagnostic methods of assessing equine uterine health using material collected by endometrial biopsy.
Effects of the cyclooxygenase inhibitor meloxicam on recovery of ischemia-injured equine jejunum.
American journal of veterinary research    June 5, 2007   Volume 68, Issue 6 614-624 doi: 10.2460/ajvr.68.6.614
Little D, Brown SA, Campbell NB, Moeser AJ, Davis JL, Blikslager AT.To determine the effect of meloxicam and flunixin meglumine on recovery of ischemia-injured equine jejunum. Methods: 18 horses. Methods: Horses received butorphanol tartrate; were treated IV with saline (0.9% NaCl) solution (SS; 12 mL; n = 6), flunixin meglumine (1.1 mg/kg; 6), or meloxicam (0.6 mg/kg; 6) 1 hour before ischemia was induced for 2 hours in a portion of jejunum; and were allowed to recover for 18 hours. Flunixin and SS treatments were repeated after 12 hours; all 3 treatments were administered immediately prior to euthanasia. Selected clinical variables, postoperative pain scores...
Septic osteitis of the distal phalanx in foals: 22 cases (1995-2002).
Journal of the American Veterinary Medical Association    June 5, 2007   Volume 230, Issue 11 1683-1690 doi: 10.2460/javma.230.11.1683
Neil KM, Axon JE, Todhunter PG, Adams PL, Caron JP, Adkins AR.To determine the clinical characteristics and outcome of foals with septic osteitis of the distal phalanx. Methods: Retrospective case series. Methods: 22 foals. Methods: Information obtained from medical records included signalment; clinical, laboratory, and radiographic findings; treatment method; and outcome. Foals included in the study had lameness referable to the foot, radiographic evidence of localized lysis or focal loss of bone density of the distal phalanx, and suppurative discharge or necrosis of the affected bone evident at surgery. Foals with a history or evidence of penetrating w...
The clinical evidence article by Proudman et al. (2007).
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 287 
Freeman DE.No abstract available
Incisional complications following exploratory celiotomy: does an abdominal bandage reduce the risk?
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 277-283 doi: 10.2746/042516407x193963
Smith LJ, Mellor DJ, Marr CM, Reid SW, Mair TS.Post operative complications following exploratory laparotomy can be potentially life-threatening, increase post operative morbidity and result in an increase in the length of hospitalisation of the affected individual. No study has evaluated the efficacy of specific strategies to reduce the incidence of post operative incisional complications. Objective: The use of an abdominal bandage following colic surgery through a celiotomy incision would significantly reduce the prevalence of post operative incisional complications. Methods: A controlled, randomised clinical trial to test the hypothesis...
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