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Topic:Disease Diagnosis
Disease diagnosis in horses involves the identification and characterization of illnesses through various diagnostic methods and tools. This process is essential for effective veterinary care and management of equine health. Techniques used in diagnosing diseases in horses include clinical examinations, laboratory tests, imaging modalities such as ultrasonography and radiography, and molecular diagnostics. Blood tests are frequently utilized to assess parameters such as complete blood count and biochemical profiles, which can indicate underlying health issues. Additionally, advancements in genetic testing and biomarker identification have enhanced the ability to detect specific diseases early. This page aggregates peer-reviewed research studies and scholarly articles that explore diagnostic methodologies, their applications, and their impact on equine health management.
Acyclicity and dyscyclicity in mares. Two trotter stud farms were visited on Mondays, Wednesdays, and Fridays during 1972 and 1973. A total of 356 mares were bored on these farms during these breeding seasons. There were 194 nursing, 113 barren, and 49 maiden mares. Of the 356 mares, 78 (21.9%) had functional disorders of the ovaries at one time or another. The functional disorders consisted of: 27 anoestrous mares after early embryonic death, 20 with low ovarian activity, 19 with multifollicular ovaries, and 12 mares with persistent corpora lutea. The following therapies were used: (a) 1000 I.U. PMSG i.v. + 10 mg stilboestrol i.m...
Equine degenerative myeloencephalopathy. Five horses of mixed breeding and 1 zebra with symmetric tetraparesis and ataxia were studied. There were 2 females and 4 males. Signs of illness were first noticed from birth to 12 months of age. Clinical and pathologic studies were performed when the animals were 4 to 24 months old. Two of the horses were related. All of the subjects had diffuse degenerative myeloencephalopathy. The degeneration was most pronounced in thoracic segments of the spinal cord. Ventral and dorsolateral funiculi were most severely affected. Axonal swelling and abnormal neuronal cell bodies were seen in the gray mat...
Fetal electrocardiography in the mare as a practical aid to diagnosing singleton and twin pregnancy. Fetal electrocardiography (FECG) in the mare has been investigated by several workers (Holmes and Darke 1968, Kanagawa and others 1967). This short paper seeks to evaluate previous work, present new findings, and provide a practical technique enabling veterinary surgeons to diagnose singleton and twin pregnancies in the latter part of pregnancy.
Purification and characterization of equine herpesvirus-induced DNA. Infection of cells with equine herpesvirus type 1 (EHV-1) or type 3 (EHV-3) resulted in the induction of a DNA polymerase activity distinguishable from host cell DNA polymerases by its high salt requirement for maximal activity. By column chromatography on DEAE-cellulose, DNA-cellulose, phosphocellulose, and hydroxyapatite, the EHV-1-induced polymerase was purified 500-fold with 1–2% recovery of total activity from the nuclei of infected hamster livers. The final enzyme preparation was homogeneous as judged by electrophoresis in sodium dodecyl sulfate-polyacrylamide gels. Calculations based ...
A general survey of tumours in the horse. Published figures from veterinary schools indicate that tumours may account for about 1 to 3 per cent of surgical cases. In this paper an account is given of clinical and pathological aspects of the tumours that are most likely to be encountered in practice, either as visibly or palpably detectable masses of tissue, or as internal tumours responsible for clinical signs. Amongst the common and important tumours dealt with, the most prominent are "equine sarcoid", squamous-cell carcinoma (of eye region and of glans penis), granulosa-cell tumours and melanomas. Well over a hundred references prov...
Ataxia in a Welsh cob filly due to a venous malformation in the thoracic spinal cord. An 8-month old Welsh Cob filly had shown progressive ataxia of the hindquarters since about 3 months of age. Autopsy revealed a venous malformation resulting in malacia in the ninth thoracic segment of the spinal cord. It is proposed that the tissue destruction associated with this congenital lesion gave rise to the ataxia.
Labeling of antilactose antibody. Affinity labeling studies with anticarbohydrate antibodies have been very limited. In earlier studies, diazoniumphenyl glycosides were employed as affinity labeling reagents for rabbit and equine anti-p-azophenyl-β-lactoside and p-azophenyl- β-galactoside antibodies. Although these antibodies were heterogeneous, it was possible to identify the labeled residues in the heavy or light chains since the modified residues had characteristic absorption spectra. With the discovery of bacterial cell walls of Streptococcus groups A and C induced antipolysaccharide antibodies of restricted heterogeneit...
In vitro cytotoxicity of serum and peripheral blood leukocytes for equine herpesvirus type 1-infected target cells. The immune response in horses following experimental infection with equine herpesvirus type 1 (EHV-1) was assessed by measuring cytotoxicity for EHV-1-infected target cells. A technique was developed, using [125I]5-iodo-2'-deoxyuridine ([125I]IUDR)-labeled equine fetal kidney cells infected with EHV-1 as the target cells. It was shown that peripheral blood leukocytes from a recovered horse were capable of lysing target cells, as measured by the loss of radio-active label. Following the experimental infection of specific-pathogen-free ponies with EHV-1, cytotoxicity was obtained with fresh auto...
Rupture of the diaphragm in the horse. Four cases of fatal diaphragmatic rupture in the horse are described. In 2 cases there was no history of injury but the other 2 animals had sustained recent thoracic trauma. Three of the horses had signs of colic and bowel obstruction complicated, in 2 cases, by respiratory embarrassment; the fourth died rapidly, presumably of shock. Previously published cases are reviewed and the causes, clinical effects, diagnosis and treatment of the disorder are discussed.
Liver fluke infection in horses and ponies. Thirty eight cases of Fasciola hepatica infection in horses with associated clinical signs are reported. A method of examining large amounts of faeces for fluke is described. A safe method of treatment for infected horses is given which involves oral medication with oxyclozanide at a dose rate of 15 ml/50 kg body weight.
A clotting defect in an Arab colt foal. A multiple clotting defect in a 3 month old Arab colt foal associated with a deficiency in Factors VIII, IX, and XI is described. No abnormalities in clotting factors were detected in the colt's sire, dam, half-sister and half-brother.
