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Topic:Disease Treatment
Disease treatment in horses encompasses a range of medical interventions and management strategies aimed at addressing various health conditions affecting equine species. These treatments can include pharmacological approaches, such as the administration of antibiotics, anti-inflammatory drugs, and antiparasitic medications, as well as non-pharmacological methods like physical therapy, dietary adjustments, and surgical procedures. The selection of appropriate treatments depends on the specific disease, its severity, and the individual needs of the horse. This topic brings together peer-reviewed research studies and scholarly articles that explore the efficacy, safety, and advancements in therapeutic options for equine diseases, providing insights into best practices and emerging trends in equine veterinary medicine.
[Entero-colitis in the horse. A description of 46 cases (author’s transl)]. A description is given of 46 cases of non-parasitic enteritis, treated in the Large Animal Clinic during the period 1965--77. A group of 12 horses showed an acute or peracute clinical course with rapid development of shock and high lethality (83 per cent). A smaller group of 9 horses showed a subacute course while 22 horses had chronic enteritis with intermittent diarrhoea--often semisolid like cow's dung--increased peristalsis, weight loss and, in some cases, hypoproteinaemia with subcutaneous edema. Lethality rate in this group was appr. 40 per cent. Predisposing factors--especially physical...
Isolation and characterization of antibodies to Clostridium perfringens epsilon toxin from hyperimmune horse serum. Antibodies against epsilon toxin were isolated from hyperimmune horse serum by affinity chromatography. Purified epsilon prototoxin covalently bound to Affigel 202 was used as immunosorbent, and antibodies were eluted with 6.0 M guanidine chloride. In a single run 80 mg of antibody could be recovered from a 20 microliter column of immunosorbent. The antibody was shown to belong to the IgG(T) class of immunoglobulins.
Peritoneal lavage in the horse. Eight horses ranging in age from 4 days to 9 years were treated for peritonitis. Escherichia coli was isolated in four cases and Nocardia sp in one case. In each case, a catheter placed in the peritoneal cavity allowed drainage of a large amount of purulent fluid. Retrograde peritoneal lavage was performed through a Foley catheter or medical tubing, using Ringer's lactate solution containing kanamycin, povidone iodine, or nitrofurazone. All except two horses responded well to repeated lavage.
The irritancy of chlorhexidine gluconate in the genital tract of the mare. Uterine irrigation was carried out in eight Welsh pony mares using 50 ml of chlorhexidine gluconate solution diluted to give active ingredient concentrations of 0.25 per cent to 2 per cent. Treatment was repeated up to twice in mares showing no adverse effects and irritancy of treatment judged on clinical symptoms and uterine biopsy. Results indicated the inadvisability of using a higher concentration than 0.25 per cent. Three daily applications of a diluted surgical scub solution containing 2 per cent chlorhexidine gluconate to the penis of an arab stallion failed to produce symptoms or irrit...
The Fourth Sir Frederick Hobday Memorial Lecture. Back problems in the horse–a look at past, present and future progress. The horse is predisposed to back injury by virtue of the type of work and intensity of competition
to which it is subjected nowadays. This paper reviews some of the inherent difficulties in establishing meaningful criteria for the diagnosis and treatment of these injuries. It highlights some
of the large gaps in knowledge, particularly in relation to the causative factors involved and the
biomechanics of the equine spine. One controversial area in diagnosis and treatment concerns
the possible subluxation of vertebral dorsal spinous processes and their subsequent reposition by
means of man...
A preliminary report on the use of warfarin in the treatment of navicular disease. Twenty horses suffering from navicular disease were treated with warfarin given orally. The dosage was to effect, to give a 2 to 4 second prolongation of the one stage prothrombin time (OSPT). Dosage was initially at a rate of 0.018 mg/kg, changing the dose by amounts of 20 per cent until the required dose was achieved. Final dose rates varied from 0.012 mg/kg to 0.75 mg/kg. All the cases treated received warfarin daily throughout the trial. Seventeen of the animals became sound and the remaining 3 showed a marked improvement in their gait. The mean of the ages of the horses was 7.5 years, the...
Improved measurements of shear modulus and pleural membrane tension of the lung. The continuum solution for the deformation of an elastic half space covered by a membrane is used to interpret measurements of the indentation of lung lobes under a column of fluid. The shear modulus mu of the underlying parenchyma is found to be approximately 0.7 times transpulmonary pressure, independent of species size. The tension in the pleural membrane T increases rapidly with increasing membrane area. For dog lungs, the value of T is 10(3) to 10(4) dyn/cm. For the larger species tested, pigs and horses, T is larger. The continuum solution shows that a concentrated force applied to the p...
Atypical salmonellosis in horses: fever and depression without diarrhea. Salmonellosis in horses may result in fever, anorexia, and depression without concurrent diarrhea or other obvious gastrointestinal abnormalities and should be considered in cases of fever of unknown origin. The syndrome also is characterized by neutropenia, usually with a left shift, and growth of small numbers of salmonella from feces cultured in selenite enrichment broth. Repeated culturing may be necessary to isolate the organism. All six affected horses of this report recovered in 3 to 7 days without specific therapy.
Purification of the subunit Clq from the first component of equine complement. Initial separation and concentration of Clq from fresh, normal equine serum was accomplished by precipitation in 0.02 M acetate buffer, pH 5.5, at 4 degrees for 24 h. The re-dissolved precipitate was clarified by centrifugation at 80,000 g for 1 h and then dialysed against Tris-HCl buffer (0.05 M, pH 8.0) containing 10-3 M EDTA. The clarified dialysate remained biologically active at 5 degrees for at least 4 weeks. Biological activity of equine Clq was determined by assay of its ability to agglutinate sensitized sheep erythrocytes (EA). Following ammonium sulphate fractionation, Sepharose 4B g...
Probstmayria vivipara pinworms in ponies. From 1967--1978 observations were made on the presence of the small equine pinworm, Probstmayria vivipara, in seven experimental ponies. The life cycle of this nematode is unusual in that it is endogenous with development of all stages occurring within the host's digestive tract. Initially, worms were found in the feces of four of seven ponies following treatment with thiabendazole but the infection was later transmitted to all ponies possibly via coprophagy. Still later, based on fecal and postmortem examinations, four of the seven ponies lost their pinworm burdens. At necropsy, the principal...
