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Topic:Disease

The study of diseases in horses encompasses a wide range of conditions affecting equine health, including infectious diseases, metabolic disorders, and genetic abnormalities. These diseases can impact various systems within the horse, such as respiratory, gastrointestinal, and musculoskeletal systems, and can lead to significant health challenges. Research in this area focuses on understanding the pathophysiology, diagnosis, prevention, and treatment of equine diseases. Common diseases studied include equine influenza, equine herpesvirus, and laminitis. This page provides access to peer-reviewed research studies and scholarly articles that explore the etiology, clinical presentation, and management strategies of diseases in horses, contributing to the advancement of equine veterinary medicine.
Cell phenotypic variation in normal and damaged tendons.
International journal of experimental pathology    August 19, 2007   Volume 88, Issue 4 227-235 doi: 10.1111/j.1365-2613.2007.00549.x
Clegg PD, Strassburg S, Smith RK.Injuries to tendons are common in both human athletes as well as in animals, such as the horse, which are used for competitive purposes. Furthermore, such injuries are also increasing in prevalence in the ageing, sedentary population. Tendon diseases often respond poorly to treatment and require lengthy periods of rehabilitation. The tendon has a unique extracellular matrix, which has developed to withstand the mechanical demands of such tensile-load bearing structures. Following injury, any repair process is inadequate and results in tissue that is distinct from original tendon tissue. There ...
The diversity of coliphages and coliforms in horse feces reveals a complex pattern of ecological interactions.
Applied and environmental microbiology    August 17, 2007   Volume 73, Issue 19 5975-5981 doi: 10.1128/AEM.01145-07
Golomidova A, Kulikov E, Isaeva A, Manykin A, Letarov A.The diversity of coliphages and indigenous coliform strains (ICSs) simultaneously present in horse feces was investigated by culture-based and molecular methods. The richness of coliforms (as estimated by the Chao1 method) is about 1,000 individual ICSs distinguishable by genomic fingerprinting present in a single sample of feces. This unexpectedly high value indicates that some factor limits the competition of coliform bacteria in the horse gut microbial system. In contrast, the diversity of phages active against any selected ICS is generally limited to one to three viral genotypes present in...
Pro-inflammatory and antiviral cytokine expression in vaccinated and unvaccinated horses exposed to equine influenza virus.
Vaccine    August 17, 2007   Volume 25, Issue 41 7056-7064 doi: 10.1016/j.vaccine.2007.07.059
Quinlivan M, Nelly M, Prendergast M, Breathnach C, Horohov D, Arkins S, Chiang YW, Chu HJ, Ng T, Cullinane A.Most studies of the cytokine response to influenza virus infection have been carried out in human, porcine and murine models, however the data available on equine cytokines is limited. An experimental challenge study was undertaken in unvaccinated naïve horses and horses vaccinated with a commercial inactivated influenza vaccine. The humoral antibody response to vaccination and virus challenge was measured by single radial haemolysis (SRH) assay and clinical signs of influenza and viral shedding were monitored post-challenge. Levels of three equine pro-inflammatory cytokines interleukin (IL)-...
Repair of sinocutaneous fistulae in two horses.
Australian veterinary journal    August 10, 2007   Volume 85, Issue 8 341-344 doi: 10.1111/j.1751-0813.2007.00150.x
Charman RE, Vasey JR.Chronic facial defects extending into the sinuses of two mares were repaired using periosteal flaps. Partial osseous bridging was established over the defects following repair. Previous attempts to close the defects with skin alone had failed. A periosteal flap is a simple surgical technique that provides the foundations for successful repair, despite the chronicity of some fistulae.
Left- and right-sided laparoscopic-assisted nephrectomy in standing horses with unilateral renal disease.
Veterinary surgery : VS    August 10, 2007   Volume 36, Issue 6 568-572 doi: 10.1111/j.1532-950X.2007.00306.x
Röcken M, Mosel G, Stehle C, Rass J, Litzke LF.To describe a technique for, and outcome after, left- or right-sided laparoscopic-assisted nephrectomy in standing horses with unilateral renal disease. Methods: Clinical report. Methods: Horses (n=3) with unilateral renal disease. Methods: Horses were sedated with detomidine (0.01 mg/kg intravenously [IV]) and levomethadone (0.05 mg/kg IV). Paravertebral anesthesia and infiltration-anesthesia with 2% lidocaine were used to create a surgical field incorporating the 17th intercostal space and paralumbar fossa. Two separate, ipsilateral portals and a mini-laparotomy were used. The perirenal peri...
Lentzea kentuckyensis sp. nov., of equine origin.
International journal of systematic and evolutionary microbiology    August 9, 2007   Volume 57, Issue Pt 8 1780-1783 doi: 10.1099/ijs.0.64245-0
Labeda DP, Donahue JM, Sells SF, Kroppenstedt RM.A novel actinomycete, designated strain LDDC 2876-05(T), was isolated from an equine placenta during the course of routine diagnostic tests for nocardioform placentitis. In a preliminary study, the strain was observed to be phylogenetically distinct from the genera Crossiella and Amycolatopsis and probably a member of the genus Lentzea. A polyphasic study of strain LDDC 2876-05(T) confirmed its identification as a member of Lentzea on the basis of its chemotaxonomic and morphological similarity to all of the known species of the genus. Moreover, the strain could be distinguished from other spe...
Papillary renal adenoma of distal nephron differentiation in a horse.
The Journal of veterinary medical science    August 7, 2007   Volume 69, Issue 7 763-765 doi: 10.1292/jvms.69.763
Matsuda K, Kousaka Y, Nagamine N, Tsunoda N, Taniyama H.A 20-year-old thoroughbred mare had a mass in the right kidney. The mass was encapsulated with fibrous capsule and composed of variably-sized papillary projections lined by a single layer of flattened to cuboidal neoplastic epithelial cells with no cytological and nuclear atypia. Immunohistochemically, the neoplastic cells were broadly positive for cytokeratin AE1/AE3 and granular staining for alpha-1-antitrypsin was focally detected; this immunohistochemical property was similar to that of the normal distal nephron. From these results, this case was diagnosed as papillary renal adenoma of dis...
Characterization and structure analysis of a novel bacteriocin, lacticin Z, produced by Lactococcus lactis QU 14.
Bioscience, biotechnology, and biochemistry    August 7, 2007   Volume 71, Issue 8 1984-1992 doi: 10.1271/bbb.70169
Iwatani S, Zendo T, Yoneyama F, Nakayama J, Sonomoto K.A novel bacteriocin, lacticin Z, produced by Lactococcus lactis QU 14 isolated from a horse's intestinal tract was identified. Lacticin Z was purified through a three step procedure comprised of hydrophobic-interaction, cation-exchange chromatography, and reverse-phase HPLC. ESI-TOF MS determined the molecular mass of lacticin Z to be 5,968.9 Da. The primary structure of lacticin Z was found to consist of 53 amino acid residues without any leader sequence or signal peptide. Lacticin Z showed homology to lacticin Q from L. lactis QU 5, aureocin A53 from Staphylococcus aureus A53, and mutacin BH...
Equine rescue and response activities in Louisiana in the aftermath of Hurricanes Katrina and Rita.
Journal of the American Veterinary Medical Association    August 3, 2007   Volume 231, Issue 3 384-392 doi: 10.2460/javma.231.3.384
McConnico RS, French DD, Clark B, Mortensen KE, Littlefield M, Moore RM.No abstract available
Congenital retrosternal (Morgagni) diaphragmatic hernias in three horses.
Journal of the American Veterinary Medical Association    August 3, 2007   Volume 231, Issue 3 427-432 doi: 10.2460/javma.231.3.427
Pauwels FF, Hawkins JF, MacHarg MA, Rothenbuhler RD, Baird DK, Moulton JS.3 Horses were examined and treated because of sudden onset of signs of abdominal pain. Results: All horses had a retrosternal (Morgagni) hernia involving the right side of the diaphragm. In each horse, the large colon was incarcerated in a right muscular defect in the diaphragm with a large hernial sac. Results: Definitive surgical repair of the hernia was not performed during the initial celiotomy. The hernia was repaired with mesh herniorrhaphy, but without resection of the hernia sac in 2 horses. For 1 horse, conservative management was applied. In the 2 horses treated with surgical correct...
An investigation of equine infectious anaemia infection in the central Anatolia region of Turkey.
Journal of the South African Veterinary Association    August 2, 2007   Volume 78, Issue 1 12-14 doi: 10.4102/jsava.v78i1.279
Yapklç O, Yavru S, Kale M, Bulut O, Simşek A, Sahna KC.In this study, 162 horses, 80 donkeys and 51 mule serum samples were collected in Konya city. Additionally, 64 horse serum samples from Ankara and 49 samples from Kayseri city were included in the study. A total of 406 serum samples were examined by agar gel immunodiffusion (AGID) and enzyme-linked immunosorbent assay (ELISA) for antibody to equine infectious anaemia virus (EIAV) and no positive result was detected.
Correlation between colic and antibody levels against Anoplocephala perfoliata in horses in The Netherlands.
Tijdschrift voor diergeneeskunde    July 26, 2007   Volume 132, Issue 13 508-512 
Boswinkel M, Sloet van Oldruitenborgh-Oosterbaan MM.The importance of Anoplocephala perfoliata in horses with colic was studied in 139 horses referred for colic and 139 control horses with no signs of colic for at least three years. The serodiagnostic method of Proudman and Trees, which measures the level of A. perfoliata antibody, was used to detect A. perfoliata infection. Thirty-two horses were examined at necropsy, to determine whether the presence of A. perfoliata in the ileocaecal region was associated with the A. perfoliata antibody level. The mean A. perfoliata antibody level was significantly higher in horses with colic than in horses ...
Theriogenology question of the month. Remnants of paramesonephric ducts.
Journal of the American Veterinary Medical Association    July 17, 2007   Volume 231, Issue 2 213-215 doi: 10.2460/javma.231.2.213
Kutzler MA, Hofmaster IL.No abstract available
Relationship between hair elements and severity of atrioventricular block in horses.
Biological trace element research    July 13, 2007   Volume 115, Issue 3 255-264 doi: 10.1007/BF02686000
Suzuki K, Yamaya Y, Asano K, Chiba M, Sera K, Matsumoto T, Sakai T, Asano R.The aim of this study was to investigate the relationships between the mean concentrations of trace elements and the severity of the second-degree atrioventricular (AV) block in the mane hair of horses. Electrocardiographs of horses were continually recorded for 6 h using a holter cardiac monitor to determine dropped ventricular beats (DVBs) which can be used as an indicator of the severity of the AV block. Mane hair Ca, Cu, Mg, and Zn concentrations were measured by the particle-induced X-ray emission method. The Zn/Cu ratio and Ca concentration in mane hair were significantly and positively ...
[Role of IgE-dependent reactions in atopic dermatitis].
Medycyna wieku rozwojowego    July 13, 2007   Volume 11, Issue 2 Pt 1 135-138 
Dynowski J, Wasowska-Królikowska K, Modzelewska-Hołyńska M, Tomaszewska M, Funkowicz M.Atopic dermatitis is a disease of multifactorial pathogenesis. Objective: of the study was to establish the most common allergens responsible for development of atopic symptoms in children with atopic dermatitis. Methods: the study complied 36 children aged 4 months - 3 years treated in the Department of Children Allergology, Gastroenterology and Nutrition because of atopic dermatitis. With each case the patient and family history of atopy was collected and basic laboratory tests were conducted (including total IgE and specific IgE using Polly Check system). Results: eosinophilia was found in ...
Community-associated MRSA SCCmec type IVd in Irish equids.
The Veterinary record    July 10, 2007   Volume 161, Issue 1 35-36 doi: 10.1136/vr.161.1.35
Maeda Y, Millar BC, Loughrey A, Goldsmith CE, Rooney PJ, Moore JE, Rao J, Buckley T, Egan C, Dooley JS, Lowery CJ, Matsuda M.No abstract available
Evidence-based literature pertaining to thyroid dysfunction and Cushing’s syndrome in the horse.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 329-364 doi: 10.1016/j.cveq.2007.04.004
Messer NT, Johnson PJ.The evidence-based literature pertaining to thyroid dysfunction and Cushing's syndrome is discussed in this article. Summaries of and recommendations for the treatment of these conditions are made. There is a need for reliable diagnostic tests for these conditions in horses.
Fatal brodifacoum poisoning in a pony.
The Canadian veterinary journal = La revue veterinaire canadienne    July 10, 2007   Volume 48, Issue 6 627-629 
Ayala I, Rodríguez MJ, Martos N, Zilberschtein J, Ruíz I, Motas M.Fatal brodifacoum poisoning in a pony is described; this condition has not previously been reported in ponies. Discussion of what factors in the pony's history and treatment may have predisposed to the severity and ultimate death is provided. Cet article décrit un empoisonnement mortel au brodifacoum chez un poney, condition jamais rapportée auparavant. La discussion porte sur les liens entre les divers éléments de l’anamnèse et les traitements reçus par rapport à la sévérité de la condition et ultimement à la mort de l’animal. (Traduit par Docteur André Blouin)
Evidence-based parasitology in horses.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 509-517 doi: 10.1016/j.cveq.2007.04.009
Uhlinger CA.This article focuses on what has been established concerning the interaction of equine parasites and their hosts, highlighting those issues for which convincing data are still lacking. There is a compelling need for the participation of the veterinarian in the design of appropriate anthelmintic treatments and prevention strategies.
Myocardial fibrosis in a horse with polymorphic ventricular tachycardia observed during general anesthesia.
The Canadian veterinary journal = La revue veterinaire canadienne    July 10, 2007   Volume 48, Issue 6 623-626 
Coudry V, Jean D, Desbois C, Tnibar A, Laugier C, George C.Ventricular dysrhythmias are more commonly associated with myocardial disease than are supraventricular dysrhythmias. Management of arrhythmias under general anesthesia is difficult because of the dysrhythmogenic effects of the anesthetic drugs. This report describes a severe ventricular dysrhythmia observed in a pony under general anesthesia, with a severe and old myocardial fibrosis found on postmortem examination. Fibrose du myocarde chez un cheval présentant de la tachycardie ventriculaire polymorphe observée au cours d’une anesthésie générale. Les dysrythmies ventriculaires sont pl...
Evidence-based equine upper respiratory surgery.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 229-242 doi: 10.1016/j.cveq.2007.04.002
Beard WL, Waxman S.The purpose of this article is to review the veterinary literature for various surgical procedures of the equine upper respiratory tract in an effort to evaluate the evidence supporting various therapies. This article focuses on the therapeutic benefit from more widely occurring conditions, such as laryngeal hemiplegia, dorsal displacement of the soft palate, arytenoid chondritis, and epiglottic entrapment.
Epidemiological perspectives on Hendra virus infection in horses and flying foxes.
Australian veterinary journal    July 7, 2007   Volume 85, Issue 7 268-270 doi: 10.1111/j.1751-0813.2007.00170.x
Field HE, Breed AC, Shield J, Hedlefs RM, Pittard K, Pott B, Summers PM.No abstract available
Diversity in Indian equine rotaviruses: identification of genotype G10,P6[1] and G1 strains and a new VP7 genotype (G16) strain in specimens from diarrheic foals in India.
Journal of clinical microbiology    July 7, 2007   Volume 45, Issue 7 2354 doi: 10.1128/JCM.00900-07
Gulati BR, Deepa R, Singh BK, Rao CD.No abstract available
Comparative evaluation of Rose Bengal plate agglutination test, mallein test, and some conventional serological tests for diagnosis of equine glanders. Naureen A, Saqib M, Muhammad G, Hussain MH, Asi MN.The Rose Bengal plate agglutination test (RBT) was evaluated for the diagnosis of equine glanders, and its diagnostic efficiency was compared with that of mallein and other serological tests, including indirect hemagglutination test (IHAT), complement fixation test (CFT), and modified counter immunoelectrophoresis test (mCIET). Sera from 70 naturally infected culture-positive, 96 potentially exposed cohorts, and 110 healthy equines were tested. All tests but mCIET showed 100% specificity when testing the sera from glanders-negative equines. The calculated sensitivities of RBT, IHAT, CFT, mCIET...
Dental benign cementomas in three horses.
Veterinary pathology    July 4, 2007   Volume 44, Issue 4 533-536 doi: 10.1354/vp.44-4-533
Kreutzer R, Wohlsein P, Staszyk C, Nowak M, Sill V, Baumgärtner W.Cementoma is a very rare odontogenic neoplasm of mesenchymal origin. Clinically, in 3 horses, multiple bony enlargements of the upper and lower jaw extending into the oral cavity were observed. Radiographically, multiple, well-circumscribed, radiopaque masses surrounding the roots of the upper and lower incisors or an upper premolar tooth were present. Due to malocclusion and local pain, single teeth were extracted in each case. Grossly, a hard grayish-white mass surrounding the root of the incisors and the premolars was identified. Histopathologically, the tumors consisted of excessive deposi...
The comparative morphology of three equine habronematid nematodes: SEM observations.
Parasitology research    July 4, 2007   Volume 101, Issue 5 1303-1310 doi: 10.1007/s00436-007-0637-1
Naem S.Drashia megastoma Rudolphi, 1819, Habronema muscae Carter, 1861 and Habronema microstoma Schneider, 1866 are found in the stomach of equine definitive hosts and are known to cause pathogenic effects in the stomach wall, skin, eye and occasionally other sites. These nematodes utilise either house flies or stable flies as their intermediate hosts. Apart from molecular findings that have demonstrated some of the differences between H. muscae and H. microstoma, no detailed morphological description of equine habronematid nematodes has been presented. This article describes most surface features of...
What is your diagnosis? Onchocerciasis.
Journal of the American Veterinary Medical Association    July 4, 2007   Volume 231, Issue 1 39-40 doi: 10.2460/javma.231.1.39
Metry CA, Beard DM, Simon E.No abstract available
Anaphylaxis to Mare’s milk.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology    July 3, 2007   Volume 98, Issue 6 600-602 doi: 10.1016/S1081-1206(10)60747-8
Robles S, Torres MJ, Mayorga C, Rodríguez-Bada JL, Fernández TD, Blanca M, Bartolomé B.No abstract available
Modulation of allergy incidence in icelandic horses is associated with a change in IL-4-producing T cells.
International archives of allergy and immunology    July 2, 2007   Volume 144, Issue 4 325-337 doi: 10.1159/000106459
Hamza E, Doherr MG, Bertoni G, Jungi TW, Marti E.Equine insect bite hypersensitivity (IBH) is an immediate-type hypersensitivity reaction provoked by insect-derived allergens. Icelandic horses living in Iceland do not have IBH due to absence of relevant insects, but acquire it at high frequency after being imported to mainland Europe. In contrast, their offspring born in mainland Europe has reduced IBH incidence. T helper 1 (Th1) and Th2 cells and cytokines were determined in Icelandic horses born in Iceland and on the continent and which either have IBH or are healthy. Methods: Peripheral blood mononuclear cells (PBMC) from these horses wer...
Molecular evidence for transplacental transmission of Theileria equi from carrier mares to their apparently healthy foals.
Veterinary parasitology    June 29, 2007   Volume 148, Issue 2 130-136 doi: 10.1016/j.vetpar.2007.05.017
Allsopp MT, Lewis BD, Penzhorn BL.The intra-erythrocytic parasite Theileria equi is one of two tick-transmitted causative agents of equine piroplasmosis. Piroplasms of T. equi can be transmitted across the equine placenta and once a horse is infected, it appears to remain a lifelong carrier, since anti-theilerial drugs suppress but do not eliminate the parasite. Carrier mares may transmit the organism to their offspring and this may result in abortion or neonatal piroplasmosis, but observations by some researchers suggest that foals may be born as carriers yet remain apparently healthy. Using a T. equi-specific oligonucleotide...